Carla Brackstone
YOU?
Author Swipe
View article: Review of the AMLAS Methodology for Application in Healthcare
Review of the AMLAS Methodology for Application in Healthcare Open
In recent years, the number of machine learning (ML) technologies gaining regulatory approval for healthcare has increased significantly allowing them to be placed on the market. However, the regulatory frameworks applied to them were orig…
View article: Cover Feature: Characterisation of the Carboxypeptidase G2 Catalytic Site and Design of New Inhibitors for Cancer Therapy (ChemBioChem 18/2018)
Cover Feature: Characterisation of the Carboxypeptidase G2 Catalytic Site and Design of New Inhibitors for Cancer Therapy (ChemBioChem 18/2018) Open
The cover feature picture shows the binding of a new inhibitor to the CPG2 enzyme to prevent off-site generation of an active drug as part of antibody-directed enzyme prodrug therapy (ADEPT). ADEPT involves administration of an enzyme–anti…