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View article: Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter
Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter Open
Background: This study aimed to evaluate the effectiveness of right and left atrial strain reservoir (RASr and LASr) in predicting the recurrence of atrial arrhythmias (AAs) following cavotricuspid isthmus ablation (CTIA) for typical atria…
View article: Burden of chronic spontaneous urticaria in Italy through healthcare resource utilization and direct costs: a retrospective analysis of real-world using administrative healthcare data
Burden of chronic spontaneous urticaria in Italy through healthcare resource utilization and direct costs: a retrospective analysis of real-world using administrative healthcare data Open
During the first year following the new CSU diagnosis, a lower than recommended antihistamines dispensation while an elevated use of OCS and a low and delayed omalizumab initiation after CSU exacerbation were observed, suggesting the urgen…
View article: Healthcare of patients with immunoglobulin A nephropathy through a retrospective observational study of Italian administrative data
Healthcare of patients with immunoglobulin A nephropathy through a retrospective observational study of Italian administrative data Open
Background: Immunoglobulin A nephropathy (IgAN) is a rare disease poorly described in real-world settings. Thisobservational retrospective study aimed to assess the direct healthcare burden of new IgAN patients on the ItalianNational Healt…
View article: Major cardiovascular events associated to exacerbations of chronic obstructive pulmonary disease and related health resource use: a retrospective observational study using italian administrative data
Major cardiovascular events associated to exacerbations of chronic obstructive pulmonary disease and related health resource use: a retrospective observational study using italian administrative data Open
Background Patients with chronic obstructive pulmonary disease (COPD) in Italy have a high risk of experiencing a major cardiovascular event (MACE) following an exacerbation, compared to those without prior exacerbation. After a moderate o…
View article: How to Limit Interdialytic Weight Gain in Patients on Maintenance Hemodialysis: State of the Art and Perspectives
How to Limit Interdialytic Weight Gain in Patients on Maintenance Hemodialysis: State of the Art and Perspectives Open
Background: Interdialytic weight gain (IDWG), defined as the accumulation of salt and water intake between dialysis sessions, is a critical parameter of fluid management and a marker of adherence to dietary and fluid restrictions in hemodi…
View article: Correction: Clinical characteristics, use and switch of drugs for obstructive airway diseases among patients with COPD experiencing an exacerbation: a retrospective analysis of Italian administrative healthcare data
Correction: Clinical characteristics, use and switch of drugs for obstructive airway diseases among patients with COPD experiencing an exacerbation: a retrospective analysis of Italian administrative healthcare data Open
View article: Clinical characteristics, use and switch of drugs for obstructive airway diseases among patients with COPD experiencing an exacerbation: a retrospective analysis of Italian administrative healthcare data
Clinical characteristics, use and switch of drugs for obstructive airway diseases among patients with COPD experiencing an exacerbation: a retrospective analysis of Italian administrative healthcare data Open
COPD patients receiving TT were older and had more comorbidities, especially cardiovascular diseases, than patients receiving DT or other treatments. The limited number of patients switching after exacerbation suggests that many COPD patie…
View article: Symptom Burden in Patients on Maintenance Hemodialysis: Prevalence and Severity 17 Years Apart
Symptom Burden in Patients on Maintenance Hemodialysis: Prevalence and Severity 17 Years Apart Open
Objectives: The aim of this study is to compare data from two cohorts separated by a 17-year interval. We assessed the prevalence and severity of symptoms with the “dialysis symptom index” in these two groups, recruited in 2007 and 2024, t…
View article: #2153 Difelikefalin: a new solution against itching in CKD-aP patients
#2153 Difelikefalin: a new solution against itching in CKD-aP patients Open
Background and Aims Chronic kidney disease-associated pruritus (CKD-aP) is one of the most common and burdensome symptom affecting patients with advanced chronic kidney disease, with an estimated prevalence of 53.3%. The clinical presentat…
View article: Italian healthcare resource consumption for patients on hemodialysis treated for chronic kidney disease-associated pruritus (CKD-aP)
Italian healthcare resource consumption for patients on hemodialysis treated for chronic kidney disease-associated pruritus (CKD-aP) Open
Background: Chronic kidney disease-associated pruritus (CKD-aP) affects patients on hemodialysis. This study identified hemodialysis patients presumably affected or not affected by CKD-aP and integrated healthcare costs, from the perspecti…
View article: An italian real-world analysis of obstructive hypertrophic cardiomyopathy through a large administrative healthcare database
An italian real-world analysis of obstructive hypertrophic cardiomyopathy through a large administrative healthcare database Open
Background The obstructive hypertrophic cardiomyopathy (HCM) is still not curable. Pharmacological treatments and removal of excess cardiac tissue are recommended to manage symptoms. Purpose The study aimed to identify and describe patient…
View article: Do more targets allow more cancer treatments, or not?
Do more targets allow more cancer treatments, or not? Open
View article: 643 THE HEART WAS MADE TO BE BROKEN: RECURRENT TAKOTSUBO SYNDROME IN AMYOTROPHIC LATERAL SCLEROSIS
643 THE HEART WAS MADE TO BE BROKEN: RECURRENT TAKOTSUBO SYNDROME IN AMYOTROPHIC LATERAL SCLEROSIS Open
Takotsubo syndrome (TTS) is a rare cardiac disease, characterized by transient regional wall motion abnormalities without evidence of obstructive coronary artery stenoses, mainly triggered by emotion or physical stressors. Reverse Takotsub…
View article: Antiplatelet Therapy during the First Year after Acute Coronary Syndrome in a Contemporary Italian Community of over 5 Million Subjects
Antiplatelet Therapy during the First Year after Acute Coronary Syndrome in a Contemporary Italian Community of over 5 Million Subjects Open
Background: Patterns of real-world antiplatelet therapy (APT) are reported to differ from guideline recommendations. This study describes patterns of APT during the year following a hospital diagnosis of acute coronary syndrome (ACS) and p…
View article: Prescription Pattern of Monoamine Oxidase B Inhibitors Combined with Levodopa: A Retrospective Observational Analysis of Italian Healthcare Administrative Databases
Prescription Pattern of Monoamine Oxidase B Inhibitors Combined with Levodopa: A Retrospective Observational Analysis of Italian Healthcare Administrative Databases Open
View article: Secondary prevention of coronary artery disease: a retrospective observational analysis of italian healthcare administrative data
Secondary prevention of coronary artery disease: a retrospective observational analysis of italian healthcare administrative data Open
Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): ACARPIA Farmaceutici S.r.l. Background/Introduction Prevalence and mortality rates in patients with a documented coronary artery…
View article: A Retrospective Observational Analysis of Italian Reimbursed Healthcare for Patients on Hemodialysis and Treated for Chronic Kidney Disease-Associated Pruritus
A Retrospective Observational Analysis of Italian Reimbursed Healthcare for Patients on Hemodialysis and Treated for Chronic Kidney Disease-Associated Pruritus Open
Background . Chronic kidney disease-associated pruritus (CKD-aP) frequently affects patients on hemodialysis and still needs an effective treatment. This retrospective observational study characterized patients on hemodialysis potentially …
View article: Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases Open
Background: This study describes patients with coronary artery disease (CAD) who are eligible for secondary prevention and assesses their healthcare consumption and costs from the perspective of the Italian National Health Service (INHS). …
View article: Clinical epidemiology and costs of type 2 diabetic patients with or without prior coronary artery disease or stroke. A longitudinal 5-year claims-data analysis of over 7 million inhabitants
Clinical epidemiology and costs of type 2 diabetic patients with or without prior coronary artery disease or stroke. A longitudinal 5-year claims-data analysis of over 7 million inhabitants Open
Aims Contemporary, real-world data on type 2 diabetes mellitus (T2DM) are limited. We analysed prevalence, comorbidities, outcomes and costs of T2DM patients with and without coronary artery disease (CAD) or stroke in >7 million inhabit…
View article: Does the mental health system provide effective coverage to people with schizophrenic disorder? A self-controlled case series study in Italy
Does the mental health system provide effective coverage to people with schizophrenic disorder? A self-controlled case series study in Italy Open
View article: [Mutational oncology of lung cancer: molecular markers, drugs, negotiation conditions and experiences in national reference centers.]
[Mutational oncology of lung cancer: molecular markers, drugs, negotiation conditions and experiences in national reference centers.] Open
The gradual availability of genomic profiling tests and the "agnostic approvals" from FDA and EMA have opened the oncology mutational model phase, which complements and integrates the traditional hystological approach. The non-small-cell l…
View article: Prevalence, clinical impact and costs of hyperkalaemia: Special focus on heart failure
Prevalence, clinical impact and costs of hyperkalaemia: Special focus on heart failure Open
Background Hyperkalaemia is a potential life‐threatening electrolyte abnormality. Although renin‐angiotensin‐aldosterone system inhibitors (RAASi) are potentially life‐saving, they may contribute to hyperkalaemia. Methods The prevalence, c…
View article: Metastatic renal cancer: real-world evidence from a large Italian claims database
Metastatic renal cancer: real-world evidence from a large Italian claims database Open
Purpose: To assess the healthcare resources’ consumption and integrated costs of patients with renal cancer and new metastasis (mRCC), in the perspective of the Italian National Health System (NHS).
Methods: From the ReS database, through…
View article: Prevalence, prescriptions, outcomes and costs of type 2 diabetes patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabitants
Prevalence, prescriptions, outcomes and costs of type 2 diabetes patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabitants Open
Aims: To analyze the prevalence, comorbidities, outcomes and costs of type 2 diabetes mellitus (T2DM) patients with and without coronary artery disease (CAD) or stroke in a population of over 7 million inhabitants. Methods: T2DM patients w…
View article: 270 Prevalence, prescriptions, outcomes and costs of type 2 diabetic patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabitants
270 Prevalence, prescriptions, outcomes and costs of type 2 diabetic patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabitants Open
Aims Contemporary, real-world data on type 2 diabetes mellitus (T2DM) are limited. We analysed prevalence, comorbidities, outcomes and costs of T2DM patients with and without coronary artery disease (CAD) or stroke in > 7 million inhabi…
View article: PCN172 Metastatic Renal CELL Carcinoma: Incidence and Costs from a Large Italian Claims Database
PCN172 Metastatic Renal CELL Carcinoma: Incidence and Costs from a Large Italian Claims Database Open
View article: 606 Oral anticoagulants in fragile patients with percutaneous endoscopic gastrostomy and atrial fibrillation: the Origami study
606 Oral anticoagulants in fragile patients with percutaneous endoscopic gastrostomy and atrial fibrillation: the Origami study Open
Aims Randomized trials support the safety and efficacy of direct oral anticoagulants (DOACs) vs. vitamin K antagonists (VKA) in patients with nonvalvular atrial fibrillation (AF), leading to increased use of these compounds. Crushed forms …
View article: Patterns of prescription, hospitalizations and costs of herpes zoster in patients at risk, from a large Italian claims database
Patterns of prescription, hospitalizations and costs of herpes zoster in patients at risk, from a large Italian claims database Open
Purpose: This observational study aimed to investigate the incidence of herpes zoster (HZ) among at-risk subjects aged ≥50 years, characterize them and assess annual healthcare utilization and costs from the Italian National Health System …
View article: Measuring multimorbidity inequality across Italy through the multisource comorbidity score: a nationwide study
Measuring multimorbidity inequality across Italy through the multisource comorbidity score: a nationwide study Open
Background Multimorbidity is a growing concern for healthcare systems, with many countries experiencing demographic transition to older population profiles. A simple multisource comorbidity score (MCS) has been recently developed and valid…
View article: A real-world study on unmet medical needs in triptan-treated migraine: prevalence, preventive therapies and triptan use modification from a large Italian population along two years
A real-world study on unmet medical needs in triptan-treated migraine: prevalence, preventive therapies and triptan use modification from a large Italian population along two years Open