Carlos Monteagudo
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View article: Masked Autoencoder Joint Learning for Robust Spitzoid Tumor Classification
Masked Autoencoder Joint Learning for Robust Spitzoid Tumor Classification Open
Accurate diagnosis of spitzoid tumors (ST) is critical to ensure a favorable prognosis and to avoid both under- and over-treatment. Epigenetic data, particularly DNA methylation, provide a valuable source of information for this task. Howe…
View article: Eccrine Coil Elastosis: A New Dermatopathological Feature Associated With Prediabetes and Diabetes
Eccrine Coil Elastosis: A New Dermatopathological Feature Associated With Prediabetes and Diabetes Open
Background The prevalence of diabetes mellitus continues to rise. Cutaneous histological manifestations of diabetes include microangiopathy and atherosclerosis. No morphological alterations of sweat glands have been reported. However, eccr…
View article: Oncogenomic profiling of cutaneous pericytic tumours reveals distinct drivers and shared biological processes
Oncogenomic profiling of cutaneous pericytic tumours reveals distinct drivers and shared biological processes Open
To-date the genomic landscape of cutaneous pericytic tumours (PTs), which represent a morphological continuum, have not been comprehensively explored. In order to identify the driver events of PTs from across their histological spectrum, a…
View article: Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition
Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition Open
Aims A subset of superficial angiomyxomas contains epithelial elements. Rarely, especially in Carney's complex patients, arborizing adnexal proliferations are present, with some authors proposing that they could be authentic adnexal neopla…
View article: Comprehensive profiling of the mutational landscape of hidradenoma papilliferum validates key role of alterations in the PI3K/AKT pathway alterations
Comprehensive profiling of the mutational landscape of hidradenoma papilliferum validates key role of alterations in the PI3K/AKT pathway alterations Open
Background Hidradenoma papilliferum (HP) is a rare, benign epithelial tumour arising from the anogenital mammary-like glands, that occurs almost exclusively in the anogenital region of middle-aged women. To-date, genetic characterisation o…
View article: [Artículo traducido] Diferencias en el perfil mutacional del linfoma T paniculítico y la paniculitis lúpica. Nueva serie de casos
[Artículo traducido] Diferencias en el perfil mutacional del linfoma T paniculítico y la paniculitis lúpica. Nueva serie de casos Open
The mutational landscape of SPTCL is broader than previously anticipated. We describe, for the first time, the involvement of the TP53(P72R) pathogenic variant in this subgroup of tumors, consider the possible role of different genetic bac…
View article: Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma
Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma Open
Background Cutaneous leiomyosarcoma (cLMS) is a rare soft-tissue neoplasm, showing smooth muscle differentiation, that arises from the mesenchymal cells of the dermis. To date, genetic investigation of these tumours has involved studies wi…
View article: Equipping computational pathology systems with artifact processing pipelines: a showcase for computation and performance trade-offs
Equipping computational pathology systems with artifact processing pipelines: a showcase for computation and performance trade-offs Open
Background Histopathology is a gold standard for cancer diagnosis. It involves extracting tissue specimens from suspicious areas to prepare a glass slide for a microscopic examination. However, histological tissue processing procedures res…
View article: Beyond nest size: the clinicopathological spectrum of large nested melanocytic tumours and the value of comparative genomic hybridisation and messenger RNA expression analysis
Beyond nest size: the clinicopathological spectrum of large nested melanocytic tumours and the value of comparative genomic hybridisation and messenger RNA expression analysis Open
View article: Different Mutational Profiles of Subcutaneous Panniculitis-like T-cell Lymphoma and Lupus Panniculitis: An Additional Case Series
Different Mutational Profiles of Subcutaneous Panniculitis-like T-cell Lymphoma and Lupus Panniculitis: An Additional Case Series Open
The mutational landscape of SPTCL is broader than previously anticipated. We describe, for the first time, the involvement of the TP53 (P72R) pathogenic variant in this subgroup of tumors, consider the possible role of different genetic ba…
View article: Histological interpretation of spitzoid tumours: an extensive machine learning‐based concordance analysis for improving decision making
Histological interpretation of spitzoid tumours: an extensive machine learning‐based concordance analysis for improving decision making Open
The histopathological classification of melanocytic tumours with spitzoid features remains a challenging task. We confront the complexities involved in the histological classification of these tumours by proposing machine learning (ML) alg…
View article: Equipping Computational Pathology Systems with Artifact Processing Pipelines: A Showcase for Computation and Performance Trade-offs
Equipping Computational Pathology Systems with Artifact Processing Pipelines: A Showcase for Computation and Performance Trade-offs Open
Background: Histopathology is a gold standard for cancer diagnosis. It involves extracting tissue specimens from suspicious areas to prepare a glass slide for a microscopic examination. However, histological tissue processing procedures re…
View article: Equipping Computational Pathology Systems with Artifact Processing Pipelines: A Showcase for Computation and Performance Trade-offs
Equipping Computational Pathology Systems with Artifact Processing Pipelines: A Showcase for Computation and Performance Trade-offs Open
Background Histopathology is a gold standard for cancer diagnosis. It involves extracting tissue specimens from suspicious areas to prepare a glass slide for a microscopic examination. However, histological tissue processing procedures res…
View article: HistoArtifacts
HistoArtifacts Open
This dataset contains five notable histological artifacts: blur, blood (hemorrhage), air bubbles, folded tissue, and damaged tissue. This dataset is used in the following works, and a description of the dataset can be found at https://arxi…
View article: Hybrid Immunity Protection Against SARS-CoV-2 and Severe COVID-19 in Kidney Transplantation: A Retrospective, Comparative Cohort Study
Hybrid Immunity Protection Against SARS-CoV-2 and Severe COVID-19 in Kidney Transplantation: A Retrospective, Comparative Cohort Study Open
View article: Diagnostic Algorithm to Subclassify Atypical Spitzoid Tumors in Low and High Risk According to Their Methylation Status
Diagnostic Algorithm to Subclassify Atypical Spitzoid Tumors in Low and High Risk According to Their Methylation Status Open
Current diagnostic algorithms are insufficient for the optimal clinical and therapeutic management of cutaneous spitzoid tumors, particularly atypical spitzoid tumors (AST). Therefore, it is crucial to identify new markers that allow for r…
View article: A Spitzoid Tumor dataset with clinical metadata and Whole Slide Images for Deep Learning models
A Spitzoid Tumor dataset with clinical metadata and Whole Slide Images for Deep Learning models Open
Spitzoid tumors (ST) are a group of melanocytic tumors of high diagnostic complexity. Since 1948, when Sophie Spitz first described them, the diagnostic uncertainty remains until now, especially in the intermediate category known as Spitz …
View article: Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplementary Legends for Figures and Tables 1-8 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Legends for Figures and Tables 1-8 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Legends for Figures and Tables 1-8 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplemental Figure 8 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Figure 8 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Figure 8
View article: Supplemental Table 7 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Table 7 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Table 7
View article: Supplemental Tables 1, 2, 3 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Tables 1, 2, 3 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Tables 1, 2, 3
View article: Supplemental Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplemental Figure 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Figure 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Figure 4
View article: Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplemental Figure 6A from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplemental Figure 6A from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplemental Figure 6A
View article: Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Figure 1 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Table 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplementary Figure 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Figure 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Figure 4 from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
View article: Supplementary Figures 5 and 6A-B from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Supplementary Figures 5 and 6A-B from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics Open
Supplementary Figures 5 and 6A-B from Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics