Carlos Roque D. Correia
YOU?
Author Swipe
Fluorescent Marinoquinoline Derivative as Inhibitors of <i>Plasmodium falciparum</i> : SAR Analysis, Mode of Action and In Vivo Studies Open
We present insights into the mechanism of action of marinoquinolines (MQ), a novel class of lead candidates. Using a divergent synthetic approach, we developed a series of 20 new analogues with fluorescence properties. Structure-activity r…
Enantioselective Synthesis of 3,3-Disubstituted-2,3-dihydrobenzofurans by Intramolecular Heck-Matsuda/Carbonylation/Stille Coupling Open
The enantioselective one-pot synthesis of 3,3-disubstituted-2,3-dihydrobenzofuran was developed via a strategy involving a palladium-catalyzed Heck-Matsuda reaction, followed by subsequent carbonylation and/or an organotin transmetalation …
Second‐Generation One‐Pot Enantioselective Heck‐Matsuda Arylations of Unactivated Olefins Directly from Anilines and Nitroarenes Open
A highly improved second generation of the one‐pot enantioselective Heck‐Matsuda reaction directly from anilines and nitroarenes is reported. This practical arylation method, featuring 56 examples, relies on the in situ diazotization of an…
View article: Development of highly efficient and selective palladium catalysts for telomerization of 1,3-butadiene with alcohols
Development of highly efficient and selective palladium catalysts for telomerization of 1,3-butadiene with alcohols Open
Novel phosphine ligands based on (benzo)furylphosphines, enable the efficient palladium-catalyzed telomerization of 1,3-butadiene with methanol.
View article: Combination of the structural components of amino acids with fatty acids: access to an unknown class of “fatty” α-amino acids by palladium-catalyzed amidocarbonylation
Combination of the structural components of amino acids with fatty acids: access to an unknown class of “fatty” α-amino acids by palladium-catalyzed amidocarbonylation Open
A new class of fatty amino acids, integrating fatty acids motifs, is synthesized in one step via palladium-catalyzed amidocarbonylation.
Proposing Oxalic Acid as Chemical Storage of Carbon Dioxide to Achieve Carbon Neutrality Open
Increasing emissions of carbon dioxide into the atmosphere due to the use of fossil fuels and ongoing deforestation are affecting the global climate. To reach the Paris climate agreement, in the coming decades low emission technologies mus…
Enantioselective Synthesis of Dihydrobenzofurans, Dihydrobenzosulfones, and Dihydroindoles by Merging One‐pot Intramolecular Heck‐Matsuda Reactions from Anilines with Redox‐Relay Process Open
A one‐pot tandem process was developed aiming at the concise and expeditious enantioselective synthesis of dihydrobenzofuran, dihydrobenzosulfone, and dihydroindole scaffolds under mild, and open‐flask conditions. This process combines the…
Enantioselective synthesis of β-aryl-γ-lactam derivatives via Heck–Matsuda desymmetrization of <i>N</i> -protected 2,5-dihydro-1 <i>H</i> -pyrroles Open
We report herein an enantioselective palladium-catalyzed Heck–Matsuda reaction for the desymmetrization of N -protected 2,5-dihydro-1 H -pyrroles with aryldiazonium salts, using the chiral N , N -ligand ( S )-PyraBox. This strategy has all…
Correction to “Mechanisms for the Oxidative Addition of Palladium(0) Complexes to Arenediazonium Salts” Open
ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Mechanisms for the Oxidative Addition of Palladium(0) Complexes to Arenediazonium Salts"Henrique EstevesHenrique EstevesMore …
View article: First Description of Marinoquinoline Derivatives’ Activity against Toxoplasma gondii
First Description of Marinoquinoline Derivatives’ Activity against Toxoplasma gondii Open
Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications, including neurotoxoplasmosis, a leading cause of cerebral lesions in AIDS patients. The current pharmacological treatments for toxoplasmosis fac…
Enantioselective synthesis of β-aryl-γ-lactam derivatives via Heck-Matsuda desymmetrization of <i>N</i>-protected 2,5-dihydro-1-H-pyrroles Open
We report herein an enantioselective palladium-catalyzed Heck-Matsuda reaction for the desymmetrization of N -protected 2,5-dihydro-1- H -pyrroles with aryldiazonium salts, using the chiral N - N -ligand ( S )-PyraBOx. This strategy has al…
Thermal Analysis of Arenediazonium Tetrafluoroborate Salts: Stability and Hazardous Evaluation Open
Arenediazonium salts represent an important class of aromatic organic compounds widely used as building blocks in academia and industry. Due to the high energy associated with the diazonium group, many of these salts are reported as therma…
In Tandem Enantioselective Intramolecular Heck-Matsuda Reactions directly from anilines Open
A new enantioselective intramolecular strategy for the synthesis of enantioenriched bridged benzoxacines, unsaturated spirobenzofurans, methyl-2,3-dihydrobenzofuran acetates, and methyl-2,3-indoline acetate scaffolds in a tandem-like diazo…
CCDC 2194048: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 2194049: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 2005478: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 2009242: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with <i>N</i>-Tosylhydrazones Open
A dynamic kinetic asymmetric Pd-catalyzed cross-coupling reaction of heterobiaryl bromides with ketone N-tosylhydrazones for the synthesis of heterobiaryl styrenes is described. The combination of Pd(dba)2 as a precatalyst with a TADDOL-de…
CCDC 2165277: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
How to achieve a successful Heck--Matsuda reaction based nickel complexes: Theoretical investigation of mechanistic insights aiming potencial experimental conditions and reagents Open
The catalytic cycles proposed for a Heck--Matsuda reaction mediated by nickel complexes occurring via a closed shell singlet Ni(0)/Ni(II) or via an open shell doublet Ni(I)/Ni(III) were obtained, as well as a thermodynamic analysis of its …
In Vitro Anti-Trypanosoma cruzi Activity of Halophytes from Southern Portugal Reloaded: A Special Focus on Sea Fennel (Crithmum maritimum L.) Open
Marine halophytes are an outstanding reservoir of natural products and several species have anti-infectious traditional uses. However, reports about their potential use against neglected tropical ailments, such as Chagas disease, are scarc…
CCDC 2023786: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 2014879: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 2020522: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
Ethyl 3,4-bis(acetyloxy)-2-(4-methoxyphenyl)pyrrolidine-1-carboxylate Open
The title pyrrolidine compound, C 18 H 23 NO 7 , is a tetra-substituted species in which the five-membered ring has a twisted conformation with the twist occurring in the C—C bond bearing the adjacent acetyloxy substituents; the C m —C a —…
CCDC 2015454: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …