Carmina S. Patrick
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View article: CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway
CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway Open
Cysteine-rich angiogenic inducer 61 (CYR61) promotes prostate cancer (PCa) cell growth, but its role in disease progression remains unclear. Given its insulin-like growth factor (IGF)-binding domain and the known involvement of insulin-lik…
View article: Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women
Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women Open
Breast cancer (BC) is one of the most common cancers globally. Genetic testing facilitates screening and informs targeted risk-reduction and treatments. However, genes included in testing panels are from European-ancestry studies. We condu…
View article: CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway
CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway Open
The cysteine-rich angiogenic inducer 61 (CYR61) promotes prostate cancer (PCa) cell growth, but its role in disease progression remains unclear. Given its insulin-like growth factor-binding domain and the known involvement of IGF1 in PCa, …
View article: CYR61 promotes metastasis of prostate cancer cells through the p-AKT and AR signaling pathways
CYR61 promotes metastasis of prostate cancer cells through the p-AKT and AR signaling pathways Open
Background Previous studies have shown that the cysteine-rich angiogenic inducer 61 (CYR61) contributes to prostate cancer (PCa) cell growth and survival, but its role in PCa progression is unknown. As CYR61 contains an insulin-like growth…
View article: Supplementary Data from Profiling the somatic mutational landscape of breast tumors from Hispanic/Latina women reveals conserved and unique characteristics
Supplementary Data from Profiling the somatic mutational landscape of breast tumors from Hispanic/Latina women reveals conserved and unique characteristics Open
Tables S1-S9
View article: Supplementary Data from Profiling the somatic mutational landscape of breast tumors from Hispanic/Latina women reveals conserved and unique characteristics
Supplementary Data from Profiling the somatic mutational landscape of breast tumors from Hispanic/Latina women reveals conserved and unique characteristics Open
Tables S1-S9
View article: Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics
Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics Open
Somatic mutational profiling is increasingly being used to identify potential targets for breast cancer. However, limited tumor-sequencing data from Hispanic/Latinas (H/L) are available to guide treatment. To address this gap, we performed…
View article: Supplementary Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics
Supplementary Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics Open
Tables S1-S9
View article: Supplementary Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics
Supplementary Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics Open
Tables S1-S9
View article: Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics
Data from Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics Open
Somatic mutational profiling is increasingly being used to identify potential targets for breast cancer. However, limited tumor-sequencing data from Hispanic/Latinas (H/L) are available to guide treatment. To address this gap, we performed…
View article: Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics
Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics Open
Somatic mutational profiling is increasingly being used to identify potential targets for breast cancer. However, limited tumor-sequencing data from Hispanic/Latinas (H/L) are available to guide treatment. To address this gap, we performed…
View article: Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies<i>FANCM</i>as a susceptibility gene for estrogen-receptor-negative breast cancer
Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies<i>FANCM</i>as a susceptibility gene for estrogen-receptor-negative breast cancer Open
Introduction Breast cancer (BC) is one of the most common cancers globally. Genetic testing can facilitate screening and risk-reducing recommendations, and inform use of targeted treatments. However, genes included in testing panels are fr…
View article: Variable Number Tandem Repeats (VNTRs) as modifiers of breast cancer risk in carriers of <i>BRCA1</i> 185delAG
Variable Number Tandem Repeats (VNTRs) as modifiers of breast cancer risk in carriers of <i>BRCA1</i> 185delAG Open
Despite substantial efforts in identifying both rare and common variants affecting disease risk, in the majority of diseases, a large proportion of unexplained genetic risk remains. We propose that variable number tandem repeats (VNTRs) ma…