Carol L. Wagner
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View article: Neonatal encephalopathy: a diffusional kurtosis imaging analysis of white matter to assess injury severity and recovery
Neonatal encephalopathy: a diffusional kurtosis imaging analysis of white matter to assess injury severity and recovery Open
Background Diffusional kurtosis imaging (DKI) may be more sensitive to white matter (WM) injury than diffusion tensor imaging (DTI) in infants with neonatal encephalopathy (NE) presumed from hypoxic ischemic encephalopathy (HIE). We hypoth…
View article: Prenatal vitamin D status and long-term neurocognitive outcomes: building on an emerging evidence base
Prenatal vitamin D status and long-term neurocognitive outcomes: building on an emerging evidence base Open
View article: Exploring the association between vitamin D status and Corona Virus-19 infection in a cohort of adults aged 50 years and older
Exploring the association between vitamin D status and Corona Virus-19 infection in a cohort of adults aged 50 years and older Open
View article: Effects of Maternal Pre-Pregnancy BMI on Preterm Infant Microbiome and Fecal Fermentation Profile—A Preliminary Cohort Study
Effects of Maternal Pre-Pregnancy BMI on Preterm Infant Microbiome and Fecal Fermentation Profile—A Preliminary Cohort Study Open
Objective: This feasibility, proof-of-concept study aimed to assess the impact of maternal pre-pregnancy body mass index (BMI) on preterm infant fecal fermentation and microbiome. Study Design: An infant cohort study (n = 54) in the NICU a…
View article: Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk
Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk Open
View article: Exploring the impacts of human breast milk functional lipidome on infant health and growth outcomes in early life using lipid bioinformatics
Exploring the impacts of human breast milk functional lipidome on infant health and growth outcomes in early life using lipid bioinformatics Open
Human breast milk lipidome is complex, and how changes in the functional lipid metabolism converge systematically to alter infants’ health outcomes is poorly understood. We used human breast milk and infant-mother dyads as a test system to…
View article: From frozen to feeding: storage characteristics of banked donor human milk used in a single level IV academic neonatal intensive care unit
From frozen to feeding: storage characteristics of banked donor human milk used in a single level IV academic neonatal intensive care unit Open
Background: The storage time of banked donor human milk (DHM) administered in an academic hospital to critically ill preterm neonates was previously unknown. Objective: This study was designed to determine the storage time of banked DHM by…
View article: Bayesian modeling of spatially differentiated multivariate enamel defects of the children’s primary maxillary central incisor teeth
Bayesian modeling of spatially differentiated multivariate enamel defects of the children’s primary maxillary central incisor teeth Open
Background The analysis of dental caries has been a major focus of recent work on modeling dental defect data. While a dental caries focus is of major importance in dental research, the examination of developmental defects which could also…
View article: Milk protein and HAMLET regulate the oxygen consumption rate of fetal intestinal cells and is dose-dependent
Milk protein and HAMLET regulate the oxygen consumption rate of fetal intestinal cells and is dose-dependent Open
View article: Analyzing the Responses of Enteric Bacteria to Neonatal Intensive Care Supplements
Analyzing the Responses of Enteric Bacteria to Neonatal Intensive Care Supplements Open
In the neonatal intensive care unit, adequate nutrition requires various enteral products, including human milk and formula. Human milk is typically fortified to meet increased calorie goals, and infants commonly receive vitamin mixes, iro…
View article: Multi-prong quality improvement approach for increasing mother’s own milk use for very low birth weight infants
Multi-prong quality improvement approach for increasing mother’s own milk use for very low birth weight infants Open
View article: Corrigendum to “HAMLET in human milk is resistant to digestion and carries essential free long chain polyunsaturated fatty acids and oleic acid” [Food Chem. 427 (2023) 136752]
Corrigendum to “HAMLET in human milk is resistant to digestion and carries essential free long chain polyunsaturated fatty acids and oleic acid” [Food Chem. 427 (2023) 136752] Open
View article: Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors Using Bayesian Model Selection
Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors Using Bayesian Model Selection Open
Introduction: Localized non-inheritable developmental defects of tooth enamel (DDE) are classified as enamel hypoplasia (EH), opacity (OP), and post-eruptive breakdown (PEB) using the enamel defects index. To better understan…
View article: Vitamin D and Child Neurodevelopment—A Post Hoc Analysis
Vitamin D and Child Neurodevelopment—A Post Hoc Analysis Open
Introduction: Vitamin D (VitD) has been shown to impact neurodevelopment. Studies have shown that higher 25-hydroxy-vitamin D (25(OH)D) concentrations (the indicator of vitD status) may be associated with better neurodevelopmental outcomes…
View article: Neighborhood Opportunity and Vulnerability and Incident Asthma Among Children
Neighborhood Opportunity and Vulnerability and Incident Asthma Among Children Open
Background The extent to which physical and social attributes of neighborhoods play a role in childhood asthma remains understudied. Objective To examine associations of neighborhood-level opportunity and social vulnerability measures with…
View article: Does maternal vitamin D status influence placental weight or vascular and inflammatory pathology? Secondary analysis from the Kellogg Pregnancy Study
Does maternal vitamin D status influence placental weight or vascular and inflammatory pathology? Secondary analysis from the Kellogg Pregnancy Study Open
View article: P18-058-23 Determining the Effect of Maternal Adiposity on Fecal Fermentation and Microbiome Profiles in the Preterm Infant
P18-058-23 Determining the Effect of Maternal Adiposity on Fecal Fermentation and Microbiome Profiles in the Preterm Infant Open
View article: OR02-07-23 Exploring the Impact of Maternal Vitamin D Status on the Proteomic Composition of Human Milk
OR02-07-23 Exploring the Impact of Maternal Vitamin D Status on the Proteomic Composition of Human Milk Open
View article: HAMLET in human milk is resistant to digestion and carries essential free long chain polyunsaturated fatty acids and oleic acid
HAMLET in human milk is resistant to digestion and carries essential free long chain polyunsaturated fatty acids and oleic acid Open
View article: Melasma is Associated with Lower Serum Vitamin D Concentrations as Compared to Healthy Controls
Melasma is Associated with Lower Serum Vitamin D Concentrations as Compared to Healthy Controls Open
Background Melasma is a common, chronic skin condition of hyperpigmentation involving the appearance of symmetric and irregular light brown macules and patches, mainly on sun exposed skin of the head and neck. Though the pathogenesis is no…
View article: Health Care Utilization During the COVID-19 Pandemic Among Individuals Born Preterm
Health Care Utilization During the COVID-19 Pandemic Among Individuals Born Preterm Open
Importance Limited data exist on pediatric health care utilization during the COVID-19 pandemic among children and young adults born preterm. Objective To investigate differences in health care use related to COVID-19 concerns during the p…
View article: Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021
Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021 Open
Importance The COVID-19 pandemic led to widespread lockdowns and school closures that may have affected screen time among children. Although restrictions were strongest early in the pandemic, it is unclear how screen time changed as the pa…
View article: The association of parathyroid hormone with serum 25-hydroxyvitamin during pregnancy
The association of parathyroid hormone with serum 25-hydroxyvitamin during pregnancy Open
It is currently debated whether vitamin D requirements during pregnancy differ from those during non-gravid states. In current analyses, we aimed to determine the best model for the association between PTH and serum 25-hydroxyvitamin D (25…
View article: Implementation of a Standardized Premedication Bundle to Improve Procedure Success for Nonemergent Neonatal Intubations
Implementation of a Standardized Premedication Bundle to Improve Procedure Success for Nonemergent Neonatal Intubations Open
Introduction: The American Academy of Pediatrics recommends premedication for all nonemergent neonatal intubations, yet there remains significant variation in this practice nationally. We aimed to standardize our unit’s premedication pract…
View article: Associations of Neighborhood Opportunity and Social Vulnerability With Trajectories of Childhood Body Mass Index and Obesity Among US Children
Associations of Neighborhood Opportunity and Social Vulnerability With Trajectories of Childhood Body Mass Index and Obesity Among US Children Open
Importance Physical and social neighborhood attributes may have implications for children’s growth and development patterns. The extent to which these attributes are associated with body mass index (BMI) trajectories and obesity risk from …
View article: Correction to: Costs associated with acute kidney injury in critically Ill neonates with patent Ductus arteriosus: pediatric health information system (PHIS) analysis
Correction to: Costs associated with acute kidney injury in critically Ill neonates with patent Ductus arteriosus: pediatric health information system (PHIS) analysis Open
View article: Body composition measurement for the preterm neonate: using a clinical utility framework to translate research tools into clinical care
Body composition measurement for the preterm neonate: using a clinical utility framework to translate research tools into clinical care Open
View article: Costs associated with acute kidney injury in critically Ill neonates with patent Ductus arteriosus: pediatric health information system (PHIS) analysis
Costs associated with acute kidney injury in critically Ill neonates with patent Ductus arteriosus: pediatric health information system (PHIS) analysis Open
View article: Free Fatty Acid and α-Lactalbumin-Oleic Acid Complexes in Preterm Human Milk Are Cytotoxic to Fetal Intestinal Cells in vitro
Free Fatty Acid and α-Lactalbumin-Oleic Acid Complexes in Preterm Human Milk Are Cytotoxic to Fetal Intestinal Cells in vitro Open
Human milk, the best enteral selection for a preterm infant, becomes altered during freezing and soluble free fatty acid is generated over time. Free fatty acids may form complexes, such as the oleic acid-bound protein called HAMLET (human…
View article: Breast Milk from Non-Obese Women with a High Omega-6 to Omega-3 Fatty Acid Ratio, but Not from Women with Obesity, Increases Lipogenic Gene Expression in 3T3-L1 Preadipocytes, Suggesting Adipocyte Dysfunction
Breast Milk from Non-Obese Women with a High Omega-6 to Omega-3 Fatty Acid Ratio, but Not from Women with Obesity, Increases Lipogenic Gene Expression in 3T3-L1 Preadipocytes, Suggesting Adipocyte Dysfunction Open
Maternal body mass index is associated with breast milk (BM) fatty acid composition. This study investigated the effects of BM omega (n)-6:n-3 polyunsaturated fatty acids (PUFAs) from non-obese women and women with obesity on the process o…