Carole Bougault
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View article: TgA86 Mice overexpressing transmembrane TNF display an unexpected absence of thoracolumbar disc degeneration
TgA86 Mice overexpressing transmembrane TNF display an unexpected absence of thoracolumbar disc degeneration Open
Objective. This study evaluated the relevance of TgA86 mice, which overexpress transmembrane TNF (tmTNF), as a model for intervertebral disc degeneration (IVDD). Six middle-aged, skeletally mature, transgenic TgA86 mice were included in th…
View article: Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis
Cathepsin K Inhibitors as Potential Drugs for the Treatment of Osteoarthritis Open
Links between cathepsin K and the pathophysiology of osteoarthritis (OA) can be established, not least because of the overabundance of cathepsin K in the serum of OA patients and the upregulation of cathepsin K in degraded cartilage in ani…
View article: Voluntary exercise in mice triggers an anti-osteogenic and pro-tenogenic response in the ankle joint without affecting long bones
Voluntary exercise in mice triggers an anti-osteogenic and pro-tenogenic response in the ankle joint without affecting long bones Open
View article: Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis
Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis Open
View article: POS0404 VOLUNTARY WHEEL RUNNING MODEL IN MICE TO MECHANICALLY STIMULATE THE ENTHESIS OF THE ACHILLES TENDON
POS0404 VOLUNTARY WHEEL RUNNING MODEL IN MICE TO MECHANICALLY STIMULATE THE ENTHESIS OF THE ACHILLES TENDON Open
View article: Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes
Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes Open
View article: Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes
Enhanced BMP-2/BMP-4 ratio in patients with peripheral spondyloarthritis and in cytokine- and stretch-stimulated mouse chondrocytes Open
View article: The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification
The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification Open
View article: Design, synthesis and biological evaluation of inhibitors of cathepsin K on dedifferentiated chondrocytes
Design, synthesis and biological evaluation of inhibitors of cathepsin K on dedifferentiated chondrocytes Open
View article: Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes
Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes Open
In the context of shoulder surgical replacement, a new generation of spherical interposition implants has been developed, with the implant being a mobile spacer rubbing against the glenoid cartilage and humeral bone cavity. The aim of the …
View article: Characterization of cell cultures in contact with different orthopedic implants biomaterials
Characterization of cell cultures in contact with different orthopedic implants biomaterials Open
The aim of this study is to identify the role of biological and mechanical constraints (at the cellular level) surrounding living tissues (cartilage and bone) in the presence of different joint implant biomaterials. In this fact, cells cul…
View article: Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients
Differential expression of interleukin-17 and interleukin-22 in inflamed and non-inflamed synovium from osteoarthritis patients Open