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View article: Advances in Small Molecule Activation Toward Sustainable Chemical Transformations
Advances in Small Molecule Activation Toward Sustainable Chemical Transformations Open
View article: Non-Heme Tri-Iron(II) Complex as a Precursor for Dioxygen Activation and Oxygen Reduction Reaction Catalysis
Non-Heme Tri-Iron(II) Complex as a Precursor for Dioxygen Activation and Oxygen Reduction Reaction Catalysis Open
Nonheme iron catalysts are attractive for bioinspired aerobic oxidations and oxygenations, as well as for the oxygen reduction reaction (ORR), although their potential in ORR remains largely underexploited. This study presents a rare examp…
View article: Reductive Cleavage of Dioxygen Mediated by a Lewis Superacidic Bis(borane)
Reductive Cleavage of Dioxygen Mediated by a Lewis Superacidic Bis(borane) Open
The bis-(borane) o-{(C6F5)2B}2C6F4 (1) reacts with dioxygen in the presence of decamethylferrocene (FeCp*2, Cp* = pentamethylcyclopentadienyl) to de…
View article: Unraveling Photo-Driven H<sub>2</sub> Production with a Bio-Inspired NiFe Complex: Revealing an Unexpected Hydrogen Atom Source
Unraveling Photo-Driven H<sub>2</sub> Production with a Bio-Inspired NiFe Complex: Revealing an Unexpected Hydrogen Atom Source Open
Developing efficient photocatalytic systems for sustainable H2 production is a crucial step toward reducing dependence on fossil fuels. While extensive research over the past two decades has focused on bioinspired FeFe catalysts…
View article: Tuning the Electronic and Molecular Structures of Bioinspired Heterodinuclear NiFe Catalyst for Enhanced Catalytic H<sub>2</sub> Evolution
Tuning the Electronic and Molecular Structures of Bioinspired Heterodinuclear NiFe Catalyst for Enhanced Catalytic H<sub>2</sub> Evolution Open
With the aim of enhancing the HER activity of the previously described bioinspired [NiFe]-hydrogenase complex [LN2S2NiIIFeIICp-(CO)]+ (LNiFe, with LN2S2 = 2,2'-(2,2'-bipyridine-…
View article: Fe( <scp>ii</scp> ) bidentate complexes with long-lived triplet states
Fe( <span>ii</span> ) bidentate complexes with long-lived triplet states Open
The excitation of bidentate quinoline/quinoxaline-NHC iron( ii ) complexes at 530 nm produced 3 MC/ 3 MLCT mixed excited states with lifetimes up to 74 ps.
View article: Bio‐Inspired Thiolate‐Fe<sup>II</sup>‐Hydrazine Adduct Towards Iron‐Mediated C−N Bond Formation
Bio‐Inspired Thiolate‐Fe<sup>II</sup>‐Hydrazine Adduct Towards Iron‐Mediated C−N Bond Formation Open
The bio‐inspired dinuclear iron(II) complex [Fe II (L)]₂ (L 2− =2,2’‐(2,2’‐bipyridine‐6,6’‐diyl)bis(1,1’‐diphenylethanethiolate)), featuring alkyl thiolate ligands, was found to react with hydrazine (N₂H₄) to form an unprecedented alkyl th…
View article: Outstanding Superoxide Dismutase Catalytic Activity Of Simple Peptide‐Based Nickel(II) Complexes
Outstanding Superoxide Dismutase Catalytic Activity Of Simple Peptide‐Based Nickel(II) Complexes Open
We present here the most active synthetic Ni superoxide dismutase (NiSOD) mimic reported to date. Reactive oxygen species are aggressive compounds, which concentrations are tightly regulated in vivo. Among them, the superoxide anion, O 2 ⋅…
View article: Chromium–Thiolate Complex Undergoing C–S Bond Cleavage
Chromium–Thiolate Complex Undergoing C–S Bond Cleavage Open
The cleavage of C-S bonds represents a crucial step in fossil fuel refinement to remove organosulfur impurities. Efforts are required to identify alternatives that can replace the energy-intensive hydrodesulfurization process currently in …
View article: A Non‐Macrocycle Thiolate‐Based Cobalt Catalyst for Selective O<sub>2</sub> Reduction into H<sub>2</sub>O
A Non‐Macrocycle Thiolate‐Based Cobalt Catalyst for Selective O<sub>2</sub> Reduction into H<sub>2</sub>O Open
The reduction of dioxygen to produce selectively H 2 O 2 or H 2 O is crucial in various fields. While platinum‐based materials excel in 4H + /4e − oxygen reduction reaction (ORR) catalysis, cost and resource limitations drive the search fo…
View article: Oxygen-Donor Metalloligands Induce Slow Magnetization Relaxation in Zero Field for a Cobalt(II) Complex with {CoO<sub>4</sub>} Motif
Oxygen-Donor Metalloligands Induce Slow Magnetization Relaxation in Zero Field for a Cobalt(II) Complex with {CoO<sub>4</sub>} Motif Open
Most 3d metal-based single-molecule magnets (SMMs) use N-ligands or ligands with even softer donors to impart a particular coordination geometry and increase the zero-field splitting parameter |D|, while complexes with hard O-donor …
View article: Drug Discovery and Development
Drug Discovery and Development Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTDrug Discovery and DevelopmentCarole Duboc*Carole Duboc*Email: [email protected]More by Carole Dubochttps://orcid.org/0000-0002-9415-198X and Sabine L. Flitsch*Sabine L. Flitsch*Email: [email prote…
View article: Class Ib Ribonucleotide Reductases: Activation of a Peroxido-Mn<sup>II</sup>Mn<sup>III</sup> to Generate a Reactive Oxo-Mn<sup>III</sup>Mn<sup>IV</sup> Oxidant
Class Ib Ribonucleotide Reductases: Activation of a Peroxido-Mn<sup>II</sup>Mn<sup>III</sup> to Generate a Reactive Oxo-Mn<sup>III</sup>Mn<sup>IV</sup> Oxidant Open
In the postulated catalytic cycle of class Ib Mn2 ribonucleotide reductases (RNRs), a MnII2 core is suggested to react with superoxide (O2·-) to generate peroxido-MnIIMn
View article: ClO2-Mediated Oxidation of the TEMPO Radical: Fundamental Considerations of the Catalytic System for the Oxidation of Cellulose Fibers
ClO2-Mediated Oxidation of the TEMPO Radical: Fundamental Considerations of the Catalytic System for the Oxidation of Cellulose Fibers Open
The reaction mechanism of ClO2-mediated TEMPO oxidation was investigated by EPR spectroscopy and UV–Vis spectroscopy in the context of an alternative TEMPO sequence for cellulose fiber oxidation. Without the presence of a cellulosic substr…
View article: Light‐Triggered Nickel‐Catalyzed Azide−Alkyne Cycloaddition for the Preparation of 1,5‐Disubstituted 1,2,3‐Triazoles
Light‐Triggered Nickel‐Catalyzed Azide−Alkyne Cycloaddition for the Preparation of 1,5‐Disubstituted 1,2,3‐Triazoles Open
When irradiated by UVA, a Ni(II) precatalyst integrating a benzophenone chromophore in its structure catalyzes the regioselective cycloaddition of alkynes and azides to produce 1,5‐disubsituted 1,2,3‐triazoles with 1,5:1,4 regioisomer rati…
View article: CCDC 2133093: Experimental Crystal Structure Determination
CCDC 2133093: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Dual Photoredox Ni/Benzophenone Catalysis: A Study of the Ni<sup>II</sup> Precatalyst Photoreduction Step
Dual Photoredox Ni/Benzophenone Catalysis: A Study of the Ni<sup>II</sup> Precatalyst Photoreduction Step Open
The combination of NiIIX2 salts with a bipyridine-type ligand and aromatic carbonyl-based chromophores has emerged as a benchmark precatalytic system to efficiently conduct cross-couplings mediated by light. Mechanist…
View article: New Chemical Tools for Diagnosis and Treatment of Cancer
New Chemical Tools for Diagnosis and Treatment of Cancer Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTNew Chemical Tools for Diagnosis and Treatment of CancerSabine Flitsch*Sabine FlitschMore by Sabine Flitschhttps://orcid.org/0000-0003-3974-646X, Carole DubocCarole DubocMore by Carole Dubochttps:/…
View article: A bio-inspired heterodinuclear hydrogenase CoFe complex
A bio-inspired heterodinuclear hydrogenase CoFe complex Open
The performance for H 2 production of a bio-inspired CoFe complex was evaluated and compared to its two efficient FeFe and NiFe analogs. Unexpectedly, it did not show any electrocatalytic activity for H 2 production.
View article: CCDC 1574215: Experimental Crystal Structure Determination
CCDC 1574215: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: An [FeFe]‐Hydrogenase Mimic Immobilized through Simple Physiadsorption and Active for Aqueous H<sub>2</sub> Production
An [FeFe]‐Hydrogenase Mimic Immobilized through Simple Physiadsorption and Active for Aqueous H<sub>2</sub> Production Open
Mimicking hydrogenases with synthetic complexes is a promising strategy for the design of Earth‐abundant electrocatalysts for H 2 evolution as alternative to platinum. Here, we describe a bio‐inspired FeFe electrocatalyst, with a semi‐brid…
View article: Hydroxyl Radical Generation by the H2O2/CuII/Phenanthroline System under Both Neutral and Alkaline Conditions: An EPR/Spin-Trapping Investigation
Hydroxyl Radical Generation by the H2O2/CuII/Phenanthroline System under Both Neutral and Alkaline Conditions: An EPR/Spin-Trapping Investigation Open
The copper–phenanthroline complex CuI(Phen)2 was the first artificial nuclease studied in biology. The mechanism responsible for this activity involves CuII(Phen)2 and H2O2. Even if H2O2/Cu systems have been extensively studied in biology …
View article: Repurposing a Bio-Inspired NiFe Hydrogenase Model for CO<sub>2</sub> Reduction with Selective Production of Methane as the Unique C-Based Product
Repurposing a Bio-Inspired NiFe Hydrogenase Model for CO<sub>2</sub> Reduction with Selective Production of Methane as the Unique C-Based Product Open
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View article: Synergy between metals for small molecule activation: Enzymes and bio-inspired complexes
Synergy between metals for small molecule activation: Enzymes and bio-inspired complexes Open
View article: Bio-inspired, Multifunctional Metal–Thiolate Motif: From Electron Transfer to Sulfur Reactivity and Small-Molecule Activation
Bio-inspired, Multifunctional Metal–Thiolate Motif: From Electron Transfer to Sulfur Reactivity and Small-Molecule Activation Open
Sulfur-rich metalloproteins and metalloenzymes, containing strongly covalent metal-thiolate (cysteinate) or metal-sulfide bonds in their active site, are ubiquitous in nature. The metal-sulfur motif is a highly versatile tool involved in v…
View article: Correction to Lithium/Sulfur Cell Discharge Mechanism: An Original Approach for Intermediate Species Identification
Correction to Lithium/Sulfur Cell Discharge Mechanism: An Original Approach for Intermediate Species Identification Open
ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Lithium/Sulfur Cell Discharge Mechanism: An Original Approach for Intermediate Species IdentificationCéline Barchasz*Céline Ba…
View article: O<sub>2</sub> Activation by Non-Heme Thiolate-Based Dinuclear Fe Complexes
O<sub>2</sub> Activation by Non-Heme Thiolate-Based Dinuclear Fe Complexes Open
Iron centers featuring thiolates in their metal coordination sphere (as ligands or substrates) are well-known to activate dioxygen. Both heme and non-heme centers that contain iron-thiolate bonds are found in nature. Investigating the abil…
View article: Controlled O<sub>2</sub>reduction at a mixed-valent (II,I) Cu<sub>2</sub>S core
Controlled O<sub>2</sub>reduction at a mixed-valent (II,I) Cu<sub>2</sub>S core Open
Oxygen reduction reactions catalyzed by a mixed-valent copper complex reveal a tuneable H2O2/H2O selectivity at room temperature together with high stability over several cycles.
View article: Role of the Metal Ion in Bio-Inspired Hydrogenase Models: Investigation of a Homodinuclear FeFe Complex vs Its Heterodinuclear NiFe Analogue
Role of the Metal Ion in Bio-Inspired Hydrogenase Models: Investigation of a Homodinuclear FeFe Complex vs Its Heterodinuclear NiFe Analogue Open
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View article: Mononuclear Ni(II) Complexes with a S3O Coordination Sphere Based on a Tripodal Cysteine-Rich Ligand: pH Tuning of the Superoxide Dismutase Activity
Mononuclear Ni(II) Complexes with a S3O Coordination Sphere Based on a Tripodal Cysteine-Rich Ligand: pH Tuning of the Superoxide Dismutase Activity Open
The superoxide dismutase (SOD) activity of mononuclear NiII complexes, whose structures are inspired by the NiSOD, has been investigated. They have been designed with a sulfur-rich pseudopeptide ligand, derived from nitrilotriac…