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View article: Circadian clock features define novel breast cancer subtypes and shape drug sensitivity
Circadian clock features define novel breast cancer subtypes and shape drug sensitivity Open
The circadian clock regulates key physiological processes, including cellular responses to DNA damage. Circadian-based therapeutic strategies optimize treatment timing to enhance drug efficacy and minimize side effects, offering potential …
View article: Circadian Coupling Orchestrates Cell Growth
Circadian Coupling Orchestrates Cell Growth Open
Summary Single-cell circadian oscillators exchange extracellular information to sustain coherent circadian rhythms at the tissue level. Within cells, the circadian clock and the cell cycle couple, yet the mechanisms governing this interpla…
View article: Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping Open
The circadian clock, a fundamental biological regulator, governs essential cellular processes in health and disease. Circadian-based therapeutic strategies are increasingly gaining recognition as promising avenues. Aligning drug administra…