Caroline Atyeo
YOU?
Author Swipe
View article: Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques Open
View article: Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates Open
View article: 404. Impact of cross-coronavirus humoral immunity in post-acute sequelae of COVID-19 in systemic autoimmune rheumatic diseases patients
404. Impact of cross-coronavirus humoral immunity in post-acute sequelae of COVID-19 in systemic autoimmune rheumatic diseases patients Open
Background Beyond the acute illness caused by SARS-CoV-2, about one-fifth of infections unpredictably result in long-term persistence of symptoms despite the apparent clearance of infection. Insights into the mechanisms that underlie post-…
View article: A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection
A Lassa virus mRNA vaccine confers protection but does not require neutralizing antibody in a guinea pig model of infection Open
View article: Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases
Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases Open
Beyond the acute illness caused by severe acute respiratory coronavirus 2 (SARS-CoV-2) infection, about one-fifth of infections result in long-term persistence of symptoms despite the apparent clearance of infection. Insights into the mech…
View article: Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells
Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells Open
View article: A Single-Dose Intranasal Combination Panebolavirus Vaccine
A Single-Dose Intranasal Combination Panebolavirus Vaccine Open
Background Ebolaviruses Ebola (EBOV), Sudan (SUDV), and Bundibugyo (BDBV) cause severe human disease, which may be accompanied by hemorrhagic syndrome, with high case fatality rates. Monovalent vaccines do not offer cross-protection agains…
View article: Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters
Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters Open
Background Since the beginning of the COVID-19 pandemic, several variants of concern (VOC) have emerged for which there is evidence of an increase in transmissibility, more severe disease, and/or reduced vaccine effectiveness. Effective CO…
View article: Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2
Lectin Fingerprinting Distinguishes Antibody Neutralization in SARS-CoV-2 Open
To develop a method that reports on changes in SARS-CoV-2 spike glycosylation and their impact on antibody protection.
View article: Diagnostic TR-FRET assays for detection of antibodies in patient samples
Diagnostic TR-FRET assays for detection of antibodies in patient samples Open
Serological assays are important diagnostic tools for surveying exposure to the pathogen, monitoring immune response post vaccination, and managing spread of the infectious agent among the population. Current serological laboratory assays …
View article: Coronavirus Immunotherapeutic Consortium Database
Coronavirus Immunotherapeutic Consortium Database Open
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has seen multiple anti-SARS-CoV-2 antibodies being generated globally. It is difficult, however, to assemble a usef…
View article: Table of Contents
Table of Contents Open
View article: A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives protection against lethal orthopoxviral challenge
A monkeypox mRNA-lipid nanoparticle vaccine targeting virus binding, entry, and transmission drives protection against lethal orthopoxviral challenge Open
Monkeypox virus (MPXV) caused a global outbreak in 2022, fueled by behaviorally-altered and enhanced human-to-human transmission. While smallpox vaccines were rapidly deployed to curb spread and disease among those at highest risk, breakth…
View article: A single dose intranasal combination panebolavirus vaccine
A single dose intranasal combination panebolavirus vaccine Open
Ebolaviruses Ebola (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) cause severe human disease, which may be accompanied by hemorrhagic syndrome, with high case fatality rates. Monovalent vaccines do not offer cross-protection against these viru…
View article: SARS-CoV-2 Serosurveys: How Antigen, Isotype and Threshold Choices Affect the Outcome
SARS-CoV-2 Serosurveys: How Antigen, Isotype and Threshold Choices Affect the Outcome Open
Background Evaluating the performance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays and clearly articulating the utility of selected antigens, isotypes, and thresholds is crucial to understanding the pr…
View article: Relationship between Anti-Spike Antibodies and Risk of SARS-CoV-2 Infection in Infants Born to COVID-19 Vaccinated Mothers
Relationship between Anti-Spike Antibodies and Risk of SARS-CoV-2 Infection in Infants Born to COVID-19 Vaccinated Mothers Open
The goal of this study was to investigate the relationship between anti-SARS-CoV-2-Spike IgG titers passively transferred to the fetus from maternal vaccination during pregnancy and timing of infant SARS-CoV-2 infection. Pregnant, vaccinat…
View article: Impact of cross-coronavirus immunity in post-acute sequelae of COVID-19
Impact of cross-coronavirus immunity in post-acute sequelae of COVID-19 Open
Beyond the unpredictable acute illness caused by SARS-CoV-2, one-fifth of infections unpredictably result in long-term persistence of symptoms despite the apparent clearance of infection. Insights into the mechanisms that underlie post-acu…
View article: SARS-CoV-2 Serosurveys: How antigen, isotype and threshold choices affect the outcome
SARS-CoV-2 Serosurveys: How antigen, isotype and threshold choices affect the outcome Open
Background Evaluating the performance of SARS-CoV-2 serological assays and clearly articulating the utility of selected antigen, isotypes and thresholds is crucial to understanding the prevalence of infection within selected communities. M…
View article: A Beta-containing bivalent SARS-CoV-2 spike protein vaccine candidate with AS03 elicits durable and broad neutralization of variants including Omicron in macaques and confers protection in hamsters
A Beta-containing bivalent SARS-CoV-2 spike protein vaccine candidate with AS03 elicits durable and broad neutralization of variants including Omicron in macaques and confers protection in hamsters Open
Background Since the beginning of the COVID-19 pandemic, several variants of concern (VOC) have emerged for which there is evidence of an increase in transmissibility, more severe disease, and/or reduced vaccine effectiveness. Effective CO…
View article: A single immunization with a modified vaccinia Ankara vectored vaccine producing Sudan virus-like particles protects from lethal infection
A single immunization with a modified vaccinia Ankara vectored vaccine producing Sudan virus-like particles protects from lethal infection Open
A new vectored vaccine MVA-VLP-SUDV was generated against Sudan ebolavirus (SUDV) combining the advantages of the immunogenicity of a live attenuated vaccine vector (Modified Vaccinia Ankara, MVA) with the authentic conformation of virus-l…
View article: COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women
COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women Open
View article: Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection Open
Preexisting cross-reactive antibodies have been implicated in both protection and pathogenesis during subsequent infections with different dengue virus (DENV) serotypes (DENV1-4). Nonetheless, humoral immune correlates and mechanisms of pr…
View article: Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms
Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms Open
View article: COVID-19 booster dose antibody response in pregnant, lactating, and nonpregnant women
COVID-19 booster dose antibody response in pregnant, lactating, and nonpregnant women Open
BACKGROUND While emerging data during the SARS-CoV-2 pandemic have demonstrated robust mRNA vaccine-induced immunogenicity across populations, including pregnant and lactating individuals, the rapid waning of vaccine-induced immunity and t…
View article: Differential Kinetics of Immune Responses Elicited by Covid-19 Vaccines
Differential Kinetics of Immune Responses Elicited by Covid-19 Vaccines Open
To the Editor: Previous studies have shown that the BNT162b2 (Pfizer–BioNTech), mRNA-1273 (Moderna), and Ad26.COV2.S (Johnson & Johnson–Janssen) vaccines provide robust protective efficacy against coronavirus disease 2019 (Covid-19). Here,…
View article: Preserved recognition of Omicron spike following COVID-19 messenger RNA vaccination in pregnancy
Preserved recognition of Omicron spike following COVID-19 messenger RNA vaccination in pregnancy Open
View article: Altered Maternal Antibody Profiles in Women With Human Immunodeficiency Virus Drive Changes in Transplacental Antibody Transfer
Altered Maternal Antibody Profiles in Women With Human Immunodeficiency Virus Drive Changes in Transplacental Antibody Transfer Open
Background Human immunodeficiency virus (HIV)–exposed, uninfected (HEU) children have a higher risk of severe infection, but the causes are poorly understood. Emerging data point to altered antibody transfer in women with HIV (WHIV); howev…
View article: A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques Open
Ad26.COV2.S has demonstrated durability and clinical efficacy against symptomatic COVID-19 in humans. In this study, we report the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with singl…
View article: Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection
Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection Open
To evaluate the persistence of vaccine-induced maternal anti-S IgG in infant blood and compared persistence of infant anti-S IgG after maternal vaccination vs natural infection.
View article: Serological Markers of SARS-CoV-2 Reinfection
Serological Markers of SARS-CoV-2 Reinfection Open
As public health and social distancing guidelines loosen in the setting of waning global natural and vaccine immunity, a deeper understanding of the immunological response to reexposure and reinfection to this highly contagious pathogen is…