Caroline Bérard
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View article: Molecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model
Molecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model Open
Cardiac lymphatic alterations and insufficient lymphatic drainage have been found in cardiovascular diseases (CVDs). To unravel the mechanisms underlying lymphatic dysfunction, we applied single-cell (sc) analyses in murine heart failure (…
View article: Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells
Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells Open
Non-small cell lung cancers (NSCLCs) treated with tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) almost invariably relapse in the long term, due to the emergence of subpopulations of resistant cells. Throu…
View article: Molecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model
Molecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model Open
Cardiac lymphatics have emerged as potential targets in cardiovascular diseases (CVDs). However, we recently reported that despite extensive lymphatic expansion during experimental cardiac pressure-overload, lymphatic drainage remained ins…
View article: Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells
Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells Open
Non-small cell lung cancers (NSCLCs) treated with tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) almost invariably relapse in the long term, due to the emergence of subpopulations of resistant cells. Here …
View article: Improving high-resolution copy number variation analysis from next generation sequencing using unique molecular identifiers
Improving high-resolution copy number variation analysis from next generation sequencing using unique molecular identifiers Open
Background Recently, copy number variations (CNV) impacting genes involved in oncogenic pathways have attracted an increasing attention to manage disease susceptibility. CNV is one of the most important somatic aberrations in the genome of…
View article: UMI-Gen: a UMI-based reads simulator for variant calling evaluation in paired-end sequencing NGS libraries
UMI-Gen: a UMI-based reads simulator for variant calling evaluation in paired-end sequencing NGS libraries Open
Motivation With Next Generation Sequencing becoming more affordable every year, NGS technologies asserted themselves as the fastest and most reliable way to detect Single Nucleotide Variants (SNV) and Copy Number Variations (CNV) in cancer…
View article: UMI-Gen: a UMI-based reads simulator for variant calling evaluation in paired-end sequencing NGS libraries
UMI-Gen: a UMI-based reads simulator for variant calling evaluation in paired-end sequencing NGS libraries Open
1 Disclaimer The author has withdrawn version 2 of this manuscript due to a duplicate posting of manuscript number 027532. Therefore, the author does not wish this work to be cited as reference for the project. 775817v1 is the appropriate …
View article: Cell wall biochemical alterations during <i>Agrobacterium</i>‐mediated expression of haemagglutinin‐based influenza virus‐like vaccine particles in tobacco
Cell wall biochemical alterations during <i>Agrobacterium</i>‐mediated expression of haemagglutinin‐based influenza virus‐like vaccine particles in tobacco Open
Summary Influenza virus‐like particles ( VLP s) have been shown to induce a safe and potent immune response through both humoral and cellular responses. They represent promising novel influenza vaccines. Plant‐based biotechnology allows fo…