Caroline Derrick
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View article: Implementation of a pilot program of interprofessional education in infection prevention
Implementation of a pilot program of interprofessional education in infection prevention Open
View article: Telehealth or in-person HIV care? Qualitative study findings on decision-making from people with HIV and HIV care providers in South Carolina during the COVID-19 pandemic
Telehealth or in-person HIV care? Qualitative study findings on decision-making from people with HIV and HIV care providers in South Carolina during the COVID-19 pandemic Open
The COVID-19 pandemic disrupted HIV care services across the United States. Telehealth was rapidly implemented to ensure HIV care continuity. Despite the evidence of unequal telehealth uptake among some people with HIV (PWH), the decision-…
View article: P-1102. Real-World Effectiveness of Dalbavancin for Invasive Gram-Positive Bacterial Infections
P-1102. Real-World Effectiveness of Dalbavancin for Invasive Gram-Positive Bacterial Infections Open
Background Emerging data suggest dalbavancin (DAL) may be used in complicated infections including bacteremia, prosthetic joints, osteomyelitis, and endovascular infections. The purpose of this study was to evaluate the real-world effectiv…
View article: Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary Open
Treatment options are currently limited for persons with HIV-1 (PWH) who are heavily treatment-experienced and/or have multidrug-resistant HIV-1. Three agents have been approved by the U.S. Food and Drug Administration (FDA) since 2018, re…
View article: Who declines “opt-out” HIV/HCV testing? Experience of an internal medicine resident continuity clinic serving a predominantly Black adult population in South Carolina.
Who declines “opt-out” HIV/HCV testing? Experience of an internal medicine resident continuity clinic serving a predominantly Black adult population in South Carolina. Open
Despite HIV/HCV testing being the standard of care, approximately one-third of eligible individuals may decline testing, the demographic characteristics of whom may overlap with individuals who are traditionally unaware of their status.
View article: Consensus recommendations for the use of novel antiretrovirals in persons with <scp>HIV</scp> who are heavily treatment‐experienced and/or have multidrug‐resistant <scp>HIV</scp>‐1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary
Consensus recommendations for the use of novel antiretrovirals in persons with <span>HIV</span> who are heavily treatment‐experienced and/or have multidrug‐resistant <span>HIV</span>‐1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary Open
Treatment options are currently limited for persons with HIV‐1 (PWH) who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1. Three agents have been approved by the U.S. Food and Drug Administration (FDA) since 2018, re…
View article: 750. Launching the South Carolina Regional Infection Prevention Training (SCRIPT) Center: A Pilot in Interprofessional Education
750. Launching the South Carolina Regional Infection Prevention Training (SCRIPT) Center: A Pilot in Interprofessional Education Open
Background Structured education of healthcare professionals around infection prevention practices and protocols is currently lacking. We launched a pilot program of an infection prevention interprofessional education (IPE) elective for stu…
View article: 1286. Evaluating Dalbavancin Suppression Therapy in Patients at High Risk for Recurrent Infections
1286. Evaluating Dalbavancin Suppression Therapy in Patients at High Risk for Recurrent Infections Open
Background Dalbavancin is a long-acting lipoglycopeptide used off-label in the treatment of deep-seated infections. An emerging potential niche for dalbavancin is chronic suppressive therapy in patients with retained sources. Limited data …
View article: 2763. Evaluating the Safety and Effectiveness of Long-term Antibiotic Suppression in Patients with Left Ventricular Assist Devices
2763. Evaluating the Safety and Effectiveness of Long-term Antibiotic Suppression in Patients with Left Ventricular Assist Devices Open
Background The utilization of left ventricular assist devices (LVADs) as a bridge to transplantation or destination therapy for non-transplant candidates continues to rise. Unfortunately, infection remains one of the most common complicati…
View article: The Future of Telehealth in Human Immunodeficiency Virus Care: A Qualitative Study of Patient and Provider Perspectives in South Carolina
The Future of Telehealth in Human Immunodeficiency Virus Care: A Qualitative Study of Patient and Provider Perspectives in South Carolina Open
To ensure care continuity during the COVID-19 pandemic, telehealth has been widely implemented in human immunodeficiency virus (HIV) care. However, participation in and benefits from telehealth were unequal. This study aims to assess the w…
View article: A survey of South Carolina pharmacists' readiness to prescribe human immunodeficiency virus pre‐exposure prophylaxis
A survey of South Carolina pharmacists' readiness to prescribe human immunodeficiency virus pre‐exposure prophylaxis Open
Introduction Human immunodeficiency virus (HIV) pre‐exposure prophylaxis (PrEP) is largely underutilized in the Southern United States. Given their community presence, pharmacists are well positioned to provide PrEP within rural, Southern …
View article: 338. Epidemiology and Treatment of Invasive <i>Bartonella spp.</i> Infections
338. Epidemiology and Treatment of Invasive <i>Bartonella spp.</i> Infections Open
Background Serology and PCR testing methods have increased ability to diagnose Bartonella spp. invasive infections. Current treatment recommendations are based primarily on case series and aging data published before newly available diagno…
View article: 2069. Prevalence of Cabotegravir and Rilpivirine Resistance Associated Mutations Among Treatment Experienced Patients in a South Carolina Outpatient Clinic
2069. Prevalence of Cabotegravir and Rilpivirine Resistance Associated Mutations Among Treatment Experienced Patients in a South Carolina Outpatient Clinic Open
Background Cabotegravir/rilpivirine (CAB/RPV) long-acting (LA) injectable was recently approved as a switch therapy for people living with HIV (PLWHIV) who are virologically suppressed on oral combination antiretroviral therapy (cART). Dat…
View article: Epidemiology, Outcomes and Tolerability of Protracted Treatment of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States
Epidemiology, Outcomes and Tolerability of Protracted Treatment of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States Open
Nontuberculous mycobacterial (NTM) infections present a treatment challenge for clinicians and patients. There are limited data about current susceptibility patterns and treatment outcomes in U.S. adults. This was a 10-year, single-center,…
View article: Crushing and Splitting Direct-Acting Antivirals for Hepatitis C Virus Treatment: A Case Series and Literature Review
Crushing and Splitting Direct-Acting Antivirals for Hepatitis C Virus Treatment: A Case Series and Literature Review Open
Limited data exist regarding the use of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) in patients who are unable to swallow tablets. This case series describes HCV treatment in patients requiring tablet manipulation, providin…
View article: 1388. Epidemiology and Treatment Outcomes of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States
1388. Epidemiology and Treatment Outcomes of Nontuberculous Mycobacterial Infections at a Community Teaching Hospital in the Southeastern United States Open
Background Gaps in evidence concerning the epidemiology of nontuberculous mycobacterial (NTM) organisms and their associated treatment outcomes are evident in the literature. The aim of this study was to describe NTM species distribution a…
View article: 1041. Tenofovir alafenamide associated weight change in persons living with HIV
1041. Tenofovir alafenamide associated weight change in persons living with HIV Open
Background Persons living with human immunodeficiency virus (PLWH) have a higher incidence of developing obesity, diabetes, and cardiovascular disease. TAF, a newer formulation of tenofovir, has favorable effects on renal function and bone…
View article: 964. Opt-Out HIV- Hepatitis C (HCV) Testing at a Primary Care Resident Clinic in Columbia, SC: Who Gets Tested and Who Opts Out of Testing?
964. Opt-Out HIV- Hepatitis C (HCV) Testing at a Primary Care Resident Clinic in Columbia, SC: Who Gets Tested and Who Opts Out of Testing? Open
Background South Carolina (SC) remains one of the most heavily affected states for both HIV and HCV infections. Males account for the majority of cases. Implementation of universal opt-out testing has improved screening rates but not much …
View article: 704. Evaluation of Risk Factors and Outcomes of Early Left Ventricular Assist Device Infections
704. Evaluation of Risk Factors and Outcomes of Early Left Ventricular Assist Device Infections Open
Background Infection is a major complication of placement of left ventricular assist devices (LVADs) for patients with end stage heart failure. This study aimed to identify risk factors and evaluate outcomes of early LVAD specific and rela…
View article: 1126. Learner Driven Call Center to increase Convalescent Plasma Donation in COVID-19
1126. Learner Driven Call Center to increase Convalescent Plasma Donation in COVID-19 Open
Background Convalescent plasma (CP) may be obtained from patients who have recovered from the novel coronavirus disease, COVID-19, caused by the virus SARS-CoV-2. Although not FDA approved, preliminary data suggests patients who receive co…
View article: 955. Addressing Gaps and Disparities in HIV testing in the Emergency Department
955. Addressing Gaps and Disparities in HIV testing in the Emergency Department Open
Background Early diagnosis of HIV is key to improving outcomes for persons living with HIV (PWH). The Emergency Department (ED) is a critical site for PWH to access care. Previous studies in South Carolina (SC) have shown that two-thirds o…
View article: Short-term Adverse Events With BIC/FTC/TAF: Postmarketing Study
Short-term Adverse Events With BIC/FTC/TAF: Postmarketing Study Open
Bictegravir (BIC)/emtricitabine (FTC)/tenofovir alafenamide (TAF) was Food and Drug Administration approved in February 2018. The paucity of real-world data prompted this retrospective, observational evaluation of discontinuation rates, ad…
View article: Heterogeneous Patient Preferences for Modern Antiretroviral Therapy: Results of a Discrete Choice Experiment
Heterogeneous Patient Preferences for Modern Antiretroviral Therapy: Results of a Discrete Choice Experiment Open
View article: Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to Enterobacter, Serratia, and Citrobacter Species
Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to Enterobacter, Serratia, and Citrobacter Species Open
Objectives: There is debate on whether the use of third-generation cephalosporins (3GC) increases the risk of clinical failure in bloodstream infections (BSIs) caused by chromosomally-mediated AmpC-producing Enterobacterales (CAE). This st…
View article: Pharmacist-Driven Culture and Sexually Transmitted Infection Testing Follow-Up Program in the Emergency Department
Pharmacist-Driven Culture and Sexually Transmitted Infection Testing Follow-Up Program in the Emergency Department Open
Expanding pharmacist-driven antimicrobial stewardship efforts in the emergency department (ED) can improve antibiotic management for both admitted and discharged patients. We piloted a pharmacist-driven culture and rapid diagnostic technol…
View article: 2493. Real-World Utilization of Ibalizumab (IBA) Without an Optimized Background Regimen (OBT)
2493. Real-World Utilization of Ibalizumab (IBA) Without an Optimized Background Regimen (OBT) Open
Background It is difficult to treat multidrug-resistant (MDR) human immunodeficiency virus (HIV). Trogarzo® (ibalizumab) a novel monoclonal antibody was approved in 2018 for heavily treatment-experienced HIV patients. Data support IBA use …
View article: 1251. Determinants of Infection at a Nontransplanting Cardiothoracic LVAD Program
1251. Determinants of Infection at a Nontransplanting Cardiothoracic LVAD Program Open
Background Left ventricular assist devices (LVADs) are a treatment option for end-stage heart failure, traditionally used as a bridge to a transplant. However, LVADs as a destination therapy is an option for individuals with contraindicati…
View article: 295. South Carolina Hepatitis C Telehealth Initiative (SCHTI): Increasing Access to HCV Care
295. South Carolina Hepatitis C Telehealth Initiative (SCHTI): Increasing Access to HCV Care Open
Background Lack of access to specialists is often a deterrent to comprehensive health care, especially in rural areas. Chronic Hepatitis C (CHC) affects 1% of the US population, and with the availability of highly efficacious treatment, it…
View article: 1950. Intentional Interprofessional Experiential Education in an HIV/Infectious Diseases Clinic
1950. Intentional Interprofessional Experiential Education in an HIV/Infectious Diseases Clinic Open
Background Experiential education opportunities, such as interprofessional practice, are currently limited in HIV care. This intentional interprofessional experiential education (IPEE) offering aimed to improve healthcare student attitudes…
View article: 1291. Comparison of Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) Screening Rates Before and After Implementation of a Quality Improvement (QI) Project Aimed at Incorporating Routine “Opt-Out” Testing at a Primary Care Resident Clinic in Columbia, SC
1291. Comparison of Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) Screening Rates Before and After Implementation of a Quality Improvement (QI) Project Aimed at Incorporating Routine “Opt-Out” Testing at a Primary Care Resident Clinic in Columbia, SC Open
Background Southern states account for the majority of new cases of Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) in the United States. Despite this, routine screening for these viruses in asymptomatic individuals remains …