Caroline G. Watts
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View article: P12.11.B MGMT METHYLATION STATUS IS STABLE AT PROGRESSION OF GLIOBLASTOMAS
P12.11.B MGMT METHYLATION STATUS IS STABLE AT PROGRESSION OF GLIOBLASTOMAS Open
BACKGROUND Promoter methylation of O6-methylguanine-DNA methyltransferase (MGMT) is associated with longer survival and with response to chemotherapy in newly diagnosed glioblastoma patients. As demethylation may form a means to treatment …
View article: A systematic review of microsimulation models for skin cancer
A systematic review of microsimulation models for skin cancer Open
Background Simulation modelling can assist with health care decision making. To inform the development and improvement of skin cancer focussed microsimulation models, we conducted a systematic review and narrative synthesis of published sk…
View article: Cost-Effectiveness of Treatment for Canine Parasites in Remote Indigenous Communities
Cost-Effectiveness of Treatment for Canine Parasites in Remote Indigenous Communities Open
View article: Impact of an online risk prediction tool for sentinel node metastasis on clinical decision-making in melanoma care: A mixed methods study
Impact of an online risk prediction tool for sentinel node metastasis on clinical decision-making in melanoma care: A mixed methods study Open
View article: Variation in initial biopsy technique for primary melanoma diagnosis: A population-based cohort study in New South Wales, Australia
Variation in initial biopsy technique for primary melanoma diagnosis: A population-based cohort study in New South Wales, Australia Open
View article: Cost and budget impact of mass drug administration compared to expanded school-based targeted preventive chemotherapy for soil-transmitted helminth control in Zamboanga Peninsula, the Philippines
Cost and budget impact of mass drug administration compared to expanded school-based targeted preventive chemotherapy for soil-transmitted helminth control in Zamboanga Peninsula, the Philippines Open
View article: Skin checks for potential skin cancers in general practice in Victoria, Australia: the upfront and downstream patterns and costs
Skin checks for potential skin cancers in general practice in Victoria, Australia: the upfront and downstream patterns and costs Open
Objectives To describe patterns of skin checks for potential skin cancers in general practice and subsequent skin-related healthcare, and the associated costs. Study type Retrospective longitudinal health record linkage. Methods Patient en…
View article: Skin checks for potential skin cancers in general practice in Victoria, Australia: the upfront and downstream patterns and costs
Skin checks for potential skin cancers in general practice in Victoria, Australia: the upfront and downstream patterns and costs Open
Objectives To describe patterns of skin checks for potential skin cancers in general practice and subsequent skin-related healthcare, and the associated costs. Study type Retrospective longitudinal health record linkage. Methods Patient en…
View article: Ignored and undervalued in public health: a systematic review of health state utility values associated with syphilis infection
Ignored and undervalued in public health: a systematic review of health state utility values associated with syphilis infection Open
View article: Acceptability and appropriateness of a risk-tailored organised melanoma screening program: Qualitative interviews with key informants
Acceptability and appropriateness of a risk-tailored organised melanoma screening program: Qualitative interviews with key informants Open
Introduction In Australia, opportunistic screening (occurring as skin checks) for the early detection of melanoma is common, and overdiagnosis is a recognised concern. Risk-tailored cancer screening is an approach to cancer control that ai…
View article: Cost and cost-effectiveness analysis of mass drug administration compared to school-based targeted preventive chemotherapy for hookworm control in Dak Lak province, Vietnam
Cost and cost-effectiveness analysis of mass drug administration compared to school-based targeted preventive chemotherapy for hookworm control in Dak Lak province, Vietnam Open
The project was funded by the National Health and Medical Research Council (NHMRC) of Australia (Project Grant APP1139561) and JPCDT was supported by a UNSW Scientia PhD Scholarship.
View article: Prognosis for people with multiple primary melanomas compared with a single primary melanoma
Prognosis for people with multiple primary melanomas compared with a single primary melanoma Open
To the Editor: People with a history of melanoma have a higher risk of developing subsequent primary melanomas than the general population; however, a difference in outcome between those with multiple primary melanomas (MPMs) and a single …
View article: The association of dermatologist demographic density with melanoma survival in New South Wales, Australia
The association of dermatologist demographic density with melanoma survival in New South Wales, Australia Open
Most Australian dermatologists (92%) work in major cities,1 limiting dermatology access to people residing in urban areas and placing a burden on rural patients to travel to major centres for such care. In the United States, higher melanom…
View article: Perspectives of health professionals and patients on implementation of a predictive model of response to immunotherapies in advanced melanoma
Perspectives of health professionals and patients on implementation of a predictive model of response to immunotherapies in advanced melanoma Open
Background Immunotherapies have significantly improved the overall survival for patients with advanced melanoma. However, almost half of such patients either do not respond to the therapy or develop resistance to it, subjecting patients to…
View article: Skin cancer-related conditions managed in general practice in Australia, 2000–2016: a nationally representative, cross-sectional survey
Skin cancer-related conditions managed in general practice in Australia, 2000–2016: a nationally representative, cross-sectional survey Open
Objective Skin cancer is Australia’s most common and costly cancer. We examined the frequency of Australian general practice consultations for skin cancer-related conditions, by patient and general practitioner (GP) characteristics and by …
View article: Diagnostic biopsies of suspected skin cancer in general practice from 2010 to 2017 in Victoria, Australia
Diagnostic biopsies of suspected skin cancer in general practice from 2010 to 2017 in Victoria, Australia Open
View article: Factors influencing acceptance, adoption and adherence to sentinel node biopsy recommendations in the Australian Melanoma Management Guidelines: a qualitative study using an implementation science framework
Factors influencing acceptance, adoption and adherence to sentinel node biopsy recommendations in the Australian Melanoma Management Guidelines: a qualitative study using an implementation science framework Open
View article: Roadmap to incorporating group A <i>Streptococcus</i> molecular point‐of‐care testing for remote Australia: a key activity to eliminate rheumatic heart disease
Roadmap to incorporating group A <i>Streptococcus</i> molecular point‐of‐care testing for remote Australia: a key activity to eliminate rheumatic heart disease Open
Strep A POCT is a critical element in preventing acute rheumatic fever and will contribute to the elimination of rheumatic heart disease in Australia Group A β-haemolytic Streptococcus pyogenes (Strep A) most commonly causes superficial in…
View article: Ignored and Undervalued in Public Health: A Systematic Review of Health State Utility Values Associated with Syphilis Infection
Ignored and Undervalued in Public Health: A Systematic Review of Health State Utility Values Associated with Syphilis Infection Open
View article: The economics of skin cancer prevention with implications for Australia and New Zealand: where are we now?
The economics of skin cancer prevention with implications for Australia and New Zealand: where are we now? Open
The incidence of skin cancer, including melanoma, continues to climb in white populations around the world, imposing a large and growing burden on health systems and individuals. Harmful exposure to ultraviolet (UV) radiation, mostly solar…
View article: Association Between Melanoma Detected During Routine Skin Checks and Mortality
Association Between Melanoma Detected During Routine Skin Checks and Mortality Open
In this cohort study, melanomas diagnosed through routine skin checks were associated with significantly lower all-cause mortality, but not melanoma-specific mortality, after adjustment for patient, sociodemographic, and clinicopathologic …
View article: Rethinking the economic costs of hospitalization for malaria: accounting for the comorbidities of malaria patients in western Kenya
Rethinking the economic costs of hospitalization for malaria: accounting for the comorbidities of malaria patients in western Kenya Open
Background Malaria causes significant mortality and morbidity in sub-Saharan Africa, especially among children under five years of age and places a huge economic burden on individuals and health systems. While this burden has been assessed…
View article: Rethinking the Economic Costs of Hospitalisation for Malaria: Accounting for the Comorbidities of Malaria Patients in Western Kenya
Rethinking the Economic Costs of Hospitalisation for Malaria: Accounting for the Comorbidities of Malaria Patients in Western Kenya Open
BackgroundMalaria causes significant mortality and morbidity in sub-Saharan Africa, especially among children under five years of age and places a huge economic burden on individuals and health systems. While this burden has been assessed …
View article: Health Utilities for Non-Melanoma Skin Cancers and Pre-Cancerous Lesions: A Systematic Review
Health Utilities for Non-Melanoma Skin Cancers and Pre-Cancerous Lesions: A Systematic Review Open
Background Non-melanoma skin cancers (NMSCs) are common and consume many healthcare resources. A health utility is a single preference-based value for assessing health-related quality of life, which can be used in economic evaluations. The…
View article: Efficiency of Detecting New Primary Melanoma Among Individuals Treated in a High-risk Clinic for Skin Surveillance
Efficiency of Detecting New Primary Melanoma Among Individuals Treated in a High-risk Clinic for Skin Surveillance Open
The structured surveillance program for high-risk patients may be implemented at a larger scale given the present cohort study findings suggesting the sustainability and replication of results in numerous settings, including a primary care…
View article: A decentralised point-of-care testing model to address inequities in the COVID-19 response
A decentralised point-of-care testing model to address inequities in the COVID-19 response Open
View article: Knowledge and attitudes of Australian dermatologists towards sentinel lymph node biopsy for melanoma: a mixed methods study
Knowledge and attitudes of Australian dermatologists towards sentinel lymph node biopsy for melanoma: a mixed methods study Open
Background/Objectives In melanoma management, sentinel lymph node biopsy (SLNB) is used to stage patients and to indicate prognosis. More recently, it has been used to select patients for adjuvant therapy. This study aimed to report knowle…
View article: Australian general practitioners’ attitudes and knowledge of sentinel lymph node biopsy in melanoma management
Australian general practitioners’ attitudes and knowledge of sentinel lymph node biopsy in melanoma management Open
GPs were generally supportive of SLNB. Familiarity with the guidelines was low, particularly regarding which patients should be considered for SLNB.
View article: GPs’ involvement in diagnosing, treating, and referring patients with suspected or confirmed primary cutaneous melanoma: a qualitative study
GPs’ involvement in diagnosing, treating, and referring patients with suspected or confirmed primary cutaneous melanoma: a qualitative study Open
Background In Australia, melanoma is managed in primary and secondary care settings. An individual concerned about a suspicious lesion typically presents first to their GP. Aim To identify factors influencing GPs’ decisions to diagnose, tr…
View article: Identifying challenges to implementation of clinical practice guidelines for sentinel lymph node biopsy in patients with melanoma in Australia: protocol paper for a mixed methods study
Identifying challenges to implementation of clinical practice guidelines for sentinel lymph node biopsy in patients with melanoma in Australia: protocol paper for a mixed methods study Open
Introduction Sentinel lymph node biopsy (SLNB) is a diagnostic procedure developed in the 1990s. It is currently used to stage patients with primary cutaneous melanoma, provide prognostic information and guide management. The Australian Cl…