Caroline Hadley
YOU?
Author Swipe
View article: The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review
The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review Open
The safety and efficacy of various pharmacotherapeutic regimens on refractory meningiomas have been the focus of investigations. We present a comprehensive review of the previous efforts and the current state of ongoing clinical trials. A …
View article: Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies
Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies Open
One-fifth of meningiomas classified as benign by World Health Organization (WHO) histopathological grading will behave malignantly. To better diagnose these tumors, several groups turned to DNA methylation, whereas we combined RNA-sequenci…
View article: ECOA-9. Integration of molecular and methylation classifications yields three meningioma groups and suggests chromosome 1p loss may be critical to the aggressive group
ECOA-9. Integration of molecular and methylation classifications yields three meningioma groups and suggests chromosome 1p loss may be critical to the aggressive group Open
Next-generation sequencing has deepened our understanding of meningiomas, particularly those that behave aggressively. Classifications using either DNA methylation profiling or RNA-sequencing predict tumor behavior more reliably than WHO g…
View article: E-159 Feasibility and safety of transradial access for pediatric neurointerventions
E-159 Feasibility and safety of transradial access for pediatric neurointerventions Open
Background Diagnostic cerebral angiograms are increasingly being performed by transradial access (TRA) in adults, following in line with data from the coronary literature supporting fewer access-site complications. Despite this ongoing tre…
View article: Elective Sonolucent Cranioplasty for Real-Time Ultrasound Monitoring of Flow and Patency of an Extra- to Intracranial Bypass
Elective Sonolucent Cranioplasty for Real-Time Ultrasound Monitoring of Flow and Patency of an Extra- to Intracranial Bypass Open
Cross-sectional imaging studies or catheter angiogram are the imaging modalities of choice to evaluate bypass patency after extra- to intracranial (EC-IC) bypass surgery. Although providing accurate results, these imaging modalities are ti…
View article: The Role of Merlin/NF2 Loss in Meningioma Biology
The Role of Merlin/NF2 Loss in Meningioma Biology Open
Mutations in the neurofibromin 2 (NF2) gene were among the first genetic alterations implicated in meningioma tumorigenesis, based on analysis of neurofibromatosis type 2 (NF2) patients who not only develop vestibular schwannomas but later…
View article: Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience
Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience Open
OBJECTIVE Following institution of the Back to Sleep Campaign, the incidence of sudden infant death syndrome decreased while the prevalence of positional skull deformation increased dramatically. The management of positional deformity is c…
View article: The health belief model and factors associated with adherence to treatment recommendations for positional plagiocephaly
The health belief model and factors associated with adherence to treatment recommendations for positional plagiocephaly Open
OBJECTIVE This study aimed to examine factors associated with adherence to recommended treatment among pediatric patients with positional skull deformity by reviewing a single-institution experience (2007–2014) with the treatment of positi…
View article: Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung
Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung Open
Taken together, these data suggest that reactive oxygen species (ROS)-induced DNA damage results in hypomethylation of the PTEN promoter, upregulation of PTEN mRNA and protein, and a subsequent increase in apoptosis in irradiated lung tiss…