Caroline Hartwell Garred
YOU?
Author Swipe
View article: Temporal trends in fatal and non-fatal heart failure admissions in Denmark from 1996 to 2022: A 25-year analysis of >180.000 patients with incident heart failure
Temporal trends in fatal and non-fatal heart failure admissions in Denmark from 1996 to 2022: A 25-year analysis of >180.000 patients with incident heart failure Open
Background Over the past 25 years, the mortality risk associated with heart failure (HF) has decreased in some countries, probably due to the implementation of evidence-based therapy. However, it remains uncertain whether HF admission rate…
View article: Patient Characteristics and Mortality Trends Among Octogenarians With Heart Failure
Patient Characteristics and Mortality Trends Among Octogenarians With Heart Failure Open
Over the past 2 decades, 2-year mortality rates in octogenarians with HF have improved despite an increase in comorbidities recorded at the time of diagnosis.
View article: Digital implementation strategy to increase SGLT2 inhibitor uptake in heart failure: Study design of EMAIL‐HF
Digital implementation strategy to increase SGLT2 inhibitor uptake in heart failure: Study design of EMAIL‐HF Open
Aims The EMAIL‐HF trial aims to evaluate whether a digital guideline implementation strategy can increase and accelerate initiation of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors in patients with heart failure (HF). Methods and resu…
View article: Associations of Body Mass Index on worsening of heart failure and mortality in patients with heart failure and reduced left ventricular ejection fraction: A 10-year follow-up study (A NorthStar Substudy)
Associations of Body Mass Index on worsening of heart failure and mortality in patients with heart failure and reduced left ventricular ejection fraction: A 10-year follow-up study (A NorthStar Substudy) Open
Background Obesity is common in heart failure with reduced ejection fraction (HFrEF). As anti-obesity treatments advance, understanding how body mass index (BMI) affects outcomes in HFrEF is increasingly important. Objective To examine whe…
View article: Kidney status and events preceding death in heart failure: A real‐world nationwide study
Kidney status and events preceding death in heart failure: A real‐world nationwide study Open
Aims Chronic kidney disease is a frequent comorbidity in heart failure (HF) patients, affecting prognosis and mortality. This study investigates the relationship between kidney function and adverse kidney events preceding death in HF patie…
View article: Temporal Trends in Mortality and Hospitalization Risk in Patients With Heart Failure According to the Hospital Frailty Risk Score
Temporal Trends in Mortality and Hospitalization Risk in Patients With Heart Failure According to the Hospital Frailty Risk Score Open
Background Heart failure (HF) and frailty often coexist. However, it is unknown how the interplay between HF and frailty at HF onset impacts prognosis of frail patients with HF and how this has evolved over time. Methods and Results We ide…
View article: Incidence of clinical outcomes in heart failure patients with and without advanced chronic kidney disease
Incidence of clinical outcomes in heart failure patients with and without advanced chronic kidney disease Open
Aims Chronic kidney disease (CKD) is a well‐established risk factor for heart failure (HF); however, patients with an estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m 2 have been systematically excluded from clinical trials. …
View article: Age-specific mortality trends in heart failure over 25 years: a retrospective Danish nationwide cohort study
Age-specific mortality trends in heart failure over 25 years: a retrospective Danish nationwide cohort study Open
Background: Despite advances in heart failure care reducing mortality in clinical trials, it remains unclear whether real-life cohorts have had similar improvements in life expectancy across the age spectrum. We aimed to investigate how mo…
View article: Temporal trends in mortality, heart failure hospitalization, and stroke in heart failure patients with and without atrial fibrillation: A nationwide study from 1997-2018 on 152,059 patients
Temporal trends in mortality, heart failure hospitalization, and stroke in heart failure patients with and without atrial fibrillation: A nationwide study from 1997-2018 on 152,059 patients Open
Background Given the many advances in treating heart failure (HF) and atrial fibrillation (AF) separately over the past decades, it remains unclear how the prognosis of patients diagnosed with both conditions has changed over time. We aime…
View article: Biochemical profiles and risk of cardiovascular events in patients withType 2 Diabetes: implications for choice of novel antihyperglycemic therapy
Biochemical profiles and risk of cardiovascular events in patients withType 2 Diabetes: implications for choice of novel antihyperglycemic therapy Open
Background Guidelines on type 2 diabetes (T2D) recommend targeting patients at greater risk of heart failure with sodium-glucose cotransporter-2 inhibitors (SGLT2-i) and patients at greater risk of cardiovascular ischemic events with gluca…
View article: Initiation of Medical Therapy for Heart Failure Patients According to Kidney Function: A Danish Nationwide Study
Initiation of Medical Therapy for Heart Failure Patients According to Kidney Function: A Danish Nationwide Study Open
In a real-world HF cohort, patients with moderate and severe kidney dysfunction were associated with reduced use of MRA irrespective of age and frailty. Reduced use of RASi was associated with severe kidney dysfunction, whereas for patient…
View article: SARS‐CoV‐2 antibody dynamics over time and risk factors associated with infection and long COVID‐19 symptoms in large working environments
SARS‐CoV‐2 antibody dynamics over time and risk factors associated with infection and long COVID‐19 symptoms in large working environments Open
Background Factors influencing SARS‐CoV‐2 antibody dynamics, transmission, waning and long COVID‐19 symptomatology are still not fully understood. Methods In the Danish section of the Novo Nordisk Group, we performed a prospective seroepid…
View article: Adherence and discontinuation of optimal heart failure therapies according to age
Adherence and discontinuation of optimal heart failure therapies according to age Open
Background Guideline-recommended disease-modifying pharmacological therapies for heart failure (HF) with reduced ejection fraction are underutilized, particularly among elderly patients. Purpose We examined adherence with and discontinuati…
View article: Adherence and Discontinuation of Optimal Heart Failure Therapies According to Age: A Danish Nationwide Study
Adherence and Discontinuation of Optimal Heart Failure Therapies According to Age: A Danish Nationwide Study Open
Background Guideline‐recommended disease‐modifying pharmacological therapies for heart failure (HF) with reduced ejection fraction are underutilized, particularly among elderly patients. We studied the association of age in adherence and d…