Caroline Midonet
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View article: Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis
Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis Open
The molecular basis of endospore formation in the model gram-positive bacterium Bacillus subtilis has been investigated for over half a century. Here, using high throughput and classical genetic approaches, we performed a comparative analy…
View article: MacP bypass variants of <i>Streptococcus pneumoniae</i> PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases
MacP bypass variants of <i>Streptococcus pneumoniae</i> PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases Open
The peptidoglycan (PG) layer protects bacteria from osmotic lysis and defines their shape. The class A penicillin-binding proteins (aPBPs) are PG synthases that possess both glycan polymerization and crosslinking activities needed for PG b…
View article: The bacterial tyrosine kinase system CpsBCD governs the length of capsule polymers
The bacterial tyrosine kinase system CpsBCD governs the length of capsule polymers Open
Significance Controlling the length of capsular polysaccharide (CPS) chains is thought to promote pathogen survival in various host niches. The polysaccharide copolymerase 2b family proteins were implicated in regulating CPS sizes. These p…
View article: The TLCΦ satellite phage harbors a Xer recombination activation factor
The TLCΦ satellite phage harbors a Xer recombination activation factor Open
Significance Cholera toxin, the principal virulence factor of Vibrio cholerae , is encoded in the genome of an integrative mobile element exploiting Xer (IMEX), CTXΦ. Nontoxigenic strains generally lack a suitable CTXΦ attachment site. In …
View article: Fast growth conditions uncouple the final stages of chromosome segregation and cell division in Escherichia coli
Fast growth conditions uncouple the final stages of chromosome segregation and cell division in Escherichia coli Open
Homologous recombination between the circular chromosomes of bacteria can generate chromosome dimers. They are resolved by a recombination event at a specific site in the replication terminus of chromosomes, dif, by dedicated tyrosine reco…
View article: How Xer-exploiting mobile elements overcome cellular control
How Xer-exploiting mobile elements overcome cellular control Open
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