Caroline Regnauld
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View article: Specific and Polyfunctional T Cell Response Against N-Methyl-d-aspartate Receptor in an Autoantibody-Mediated Encephalitis Model
Specific and Polyfunctional T Cell Response Against N-Methyl-d-aspartate Receptor in an Autoantibody-Mediated Encephalitis Model Open
Background: Anti-N-Methyl-d-aspartate receptor (NMDAR) autoimmune encephalitis (NMDAR AE) is an autoimmune disease characterized by severe psychiatric and neurological symptoms. While the pathogenic role of antibodies (Abs) directed agains…
View article: Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure
Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure Open
Background Perineuronal nets (PNNs) are specialized extracellular matrix structures mainly found around fast-spiking parvalbumin (FS-PV) interneurons. In the adult, their degradation alters FS-PV-driven functions, such as brain plasticity …
View article: Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor
Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor Open
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a neuropsychiatric disease characterized by an antibody-mediated autoimmune response against NMDAR. Recent studies have shown that anti-NMDAR antibodies are involved in the pathoph…