Carolyn Choy
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View article: ON-AIRRseq: open-sourced nanopore-based antibody immune receptor repertoire sequencing 4212
ON-AIRRseq: open-sourced nanopore-based antibody immune receptor repertoire sequencing 4212 Open
Description Monoclonal antibodies (mAbs) are indispensable in diagnostics, therapeutics, and research. However, traditional methods for studying antibody immune receptor repertoires (AIRR) in response to disease or immunization are often p…
View article: 686. SCHIZOPHRENIA-LIKE ENDOPHENOTYPES IN AMYLOID PRECURSOR PROTEIN KNOCK OUT MICE
686. SCHIZOPHRENIA-LIKE ENDOPHENOTYPES IN AMYLOID PRECURSOR PROTEIN KNOCK OUT MICE Open
Background Schizophrenia is a complex mental health condition that impacts an estimated 1% of the global population. The exact causes remain largely unclear. Recent findings from our research group have found evidence for the presence of i…
View article: 682. THE EFFECTS OF MATERNAL IMMUNE ACTIVATION ON THE PHOSPHO-PROTEOME OF THE DEVELOPING ADOLESCENT MOUSE HIPPOCAMPUS
682. THE EFFECTS OF MATERNAL IMMUNE ACTIVATION ON THE PHOSPHO-PROTEOME OF THE DEVELOPING ADOLESCENT MOUSE HIPPOCAMPUS Open
Background Prenatal infection may induce neuroinflammation in the developing foetus, which impacts neurodevelopment and predisposes emergence of neuropsychiatric disorders such as schizophrenia in adolescence. In our influenza-based prenat…
View article: 692. SEX-DEPENDENT AND DYNAMIC BRAIN STRUCTURAL MRI CHANGES IN MICE FOLLOWING INFLUENZA A VIRUS MATERNAL IMMUNE ACTIVATION
692. SEX-DEPENDENT AND DYNAMIC BRAIN STRUCTURAL MRI CHANGES IN MICE FOLLOWING INFLUENZA A VIRUS MATERNAL IMMUNE ACTIVATION Open
Background Maternal infections or inflammatory insults during pregnancy, can significantly impact brain development in the offspring, and have been associated with later neurodevelopmental disorders, including schizophrenia. Preclinical ma…
View article: Cover image: Unpeeling the layers of harlequin ichthyosis
Cover image: Unpeeling the layers of harlequin ichthyosis Open