Explanipedia

Rhythmic brain-behavior coupling in the visuo-motor system: theta-band coherence links saccades and oculomotor brain regions Open

Yvonne Buschermöhle, Jan‐Ole Radecke, Andreas Sprenger, Tim Erdbrügger, Till R. Schneider , et al. · 2025

To ensure stable visual perception, the brain requires sensorimotor integration. A propsed top-down predictive model for this integration is the internal forward model, which previously has been suggested to operate rhythmically in the the…

Lower Bound Estimates for Electrophysiological Power Dissipation in Human Gray Matter Open

Vikram Nathan, Malte B. Höltershinken, Emily Hill, Carsten H. Wolters, Sylvain Baillet · 2025

The human brain is popularly described as remarkably energy efficient, with its metabolic power consumption estimated at approximately 20 watts (W). Biophysical models have partitioned this power budget across distinct cellular processes, …

Introducing the Concept of Error Vectors to Improve Source Localization Results of Epileptic Discharges Open

Kanjana Unnwongse, Carsten H. Wolters, Tim Wehner, Lawrence Kruger, Stefan Rampp , et al. · 2025

Purpose: To improve EEG source localization results of interictal epileptic discharges (IED) by applying postprocessing step to electrical source imaging (ESI). Methods: Localization error of ESI was evaluated in comparison to known source…

Respiratory modulations of cortical excitability and interictal spike timing in focal epilepsy: a case report Open

Daniel S. Kluger, Tim Erdbrügger, Christina Stier, Malte B. Höltershinken, Omid Abbasi , et al. · 2025

Background Brain activity in focal epilepsy is marked by a pronounced excitation-inhibition (E:I) imbalance and interictal epileptiform discharges (IEDs) observed in periods between recurrent seizures. As a marker of E:I balance, aperiodic…

Multimodal personalization of transcranial direct current stimulation for modulation of sensorimotor integration Open

Jan‐Ole Radecke, Alexander Kühn, Tim Erdbrügger, Yvonne Buschermöhle, Saeid Rashidi , et al. · 2024

Transcranial direct current stimulation (tDCS) for the modulation of ongoing eye movements provides an ideal model for investigating sensorimotor integration. Within neural networks subserving smooth pursuit eye movements, visual motion ar…

Standardized Kalman filtering for dynamical source localization of concurrent subcortical and cortical brain activity Open

Joonas Lahtinen, Paavo Ronni, Narayan Puthanmadam Subramaniyam, Alexandra Koulouri, Carsten H. Wolters , et al. · 2024

SKF could help study time-evolving brain activities and localize landmarks with a deep contributor or when there is no prior knowledge of evolution.

sLORETA is equivalent to single dipole scanning Open

Malte B. Höltershinken, Tim Erdbrügger, Carsten H. Wolters · 2024

In this paper, we show that each member of a family of reconstruction approaches, which includes the classical sLORETA approach and the eLORETA approach, is exactly equivalent to a single dipole scan in some inner product norm. Additionall…

Data used for validation of the Local Subtraction Approach Open

Malte B. Höltershinken, Pia L. Lange, Tim Erdbrügger, Yvonne Buschermöhle, Fabrice Wallois , et al. · 2024

This dataset contains the volume conductor models used in the evaluation of the local subtraction approach for the EEG and MEG forward problem, as detailed in the corresponding manuscript (Published in SIAM Journal on Scientific Computing:…

Targeted and optimized multi-channel transcranial direct current stimulation for focal epilepsy: An N-of-1 trial Open

Marios Antonakakis, Fabian Kaiser, Stefan Rampp, Stjepana Kovac, Heinz Wiendl , et al. · 2024

Transcranial direct current stimulation (tDCS) has been used to noninvasively reduce epileptic activity in focal epilepsy. In this proof-of-principle N-of-1 trial in a patient with refractory focal epilepsy in left frontal lobe, we propose…

Standardized hierarchical adaptive Lp regression for noise robust focal epilepsy source reconstructions Open

Joonas Lahtinen, Alexandra Koulouri, Stefan Rampp, Jörg Wellmer, Carsten H. Wolters , et al. · 2023

The proposed standardized methodology, especially when employing the L1-norm, could serve as a valuable assessment tool in surgical decision-making.

Standardized Kalman Filtering for Time Serial Source Localization of Simultaneous Subcortical and Cortical Brain Activity Open

Joonas Lahtinen, Narayan Puthanmadam Subramaniyam, Alexandra Koulouri, Carsten H. Wolters, Sampsa Pursiainen · 2023

In this article, we present a new Bayesian filtering method for non-invasive electroencephalography (EEG) that is capable of reconstructing spatiotemporal brain activity, including both cortical and weakly detectable deep components. Our a…

Standardized Kalman Filtering for Time Serial Source Localization of Simultaneous Subcortical and Cortical Brain Activity Open

Joonas Lahtinen, Narayan Puthanmadam Subramaniyam, Alexandra Koulouri, Carsten H. Wolters, Sampsa Pursiainen · 2023

In this article, we present a new Bayesian filtering method for non-invasive electroencephalography (EEG) that is capable of reconstructing spatiotemporal brain activity, including both cortical and weakly detectable deep components. Our a…

Targeted and optimized multi-channel transcranial direct current stimulation for focal epilepsy: An N-of-1 trial Open

Marios Antonakakis, Fabian Kaiser, Stefan Rampp, Stjepana Kovac, Heinz Wiendl , et al. · 2023

Transcranial direct current stimulation (tDCS) has been used to noninvasively reduce epileptic activity in focal epilepsy. In this proof-of-principle N-of-1 trial in a patient with drug-resistant focal epilepsy, we propose distributed cons…

Respiratory modulations of cortical excitability and interictal spike timing in focal epilepsy - a case report Open

Daniel S. Kluger, Tim Erdbrügger, Christina Stier, Malte B. Höltershinken, Omid Abbasi , et al. · 2023

Summary Brain activity in focal epilepsy is marked by a pronounced excitation-inhibition (E:I) imbalance and interictal epileptiform discharges (IEDs) observed in periods between recurrent seizures. As a marker of E:I balance, aperiodic ne…

The Effects of Peeling on Finite Element Method -based EEG Source Reconstruction Open

Santtu Söderholm, Joonas Lahtinen, Carsten H. Wolters, Sampsa Pursiainen · 2023

The problem of reconstructing brain activity from electric potential measurements performed on the surface of a human head is not an easy task: not just because the solution of the related inverse problem is fundamentally ill-posed (not un…

The Local Subtraction Approach For EEG and MEG Forward Modeling Open

Malte B. Höltershinken, Pia L. Lange, Tim Erdbrügger, Yvonne Buschermöhle, Fabrice Wallois , et al. · 2023

EDIT: A revised version of this article has been published in the SIAM Journal on Scientific Computing, see https://epubs.siam.org/doi/full/10.1137/23M1582874. In the revised version, the name of the approach was changed from "localized su…

The Local Subtraction Approach For EEG and MEG Forward Modeling Open

Malte B. Höltershinken, Pia L. Lange, Tim Erdbrügger, Yvonne Buschermöhle, Fabrice Wallois , et al. · 2023

EDIT: A revised version of this article has been published in the SIAM Journal on Scientific Computing, see https://epubs.siam.org/doi/full/10.1137/23M1582874. In the revised version, the name of the approach was changed from "localized su…

Data used for validation of the Local Subtraction Approach Open

Malte B. Höltershinken, Pia L. Lange, Tim Erdbrügger, Yvonne Buschermöhle, Fabrice Wallois , et al. · 2023

This dataset contains the volume conductor models used in the evaluation of the local subtraction approach for the EEG and MEG forward problem, as detailed in the corresponding manuscript (Preprint available at: https://arxiv.org/abs/2302.…

Personalized alpha-tACS targeting left posterior parietal cortex modulates visuo-spatial attention and posterior evoked EEG activity Open

Jan‐Ole Radecke, Marina Fiene, Jonas Misselhorn, Christoph S. Herrmann, Andreas K. Engel , et al. · 2023

Background Covert visuo-spatial attention is marked by the anticipatory lateralization of neuronal alpha activity in the posterior parietal cortex. Previous applications of transcranial alternating current stimulation (tACS) at the alpha f…

Personalized transcranial alternating current stimulation targeting the dorsal attention network specifically modulates visuo-spatial attention Open

Jan‐Ole Radecke, Marina Fiene, Jonas Misselhorn, Carsten H. Wolters, Rebekka Lencer , et al. · 2023

During intentional shifts of visuo-spatial attention, transcranial alternating current stimulation (tACS) in the alpha frequency range has been shown to modulate attention. A proposed effector of this phenomenon is the modulation of neural…

A cut finite element method for the tDCS forward problem Open

Tim Erdbrügger, Yvonne Buschermöhle, Joachim Groß, Malte B. Höltershinken, Rebekka Lencer , et al. · 2023

Comparing the Performance of Beamformer Algorithms in Estimating Orientations of Neural Sources Open

Yvonne Buschermöhle, Malte B. Höltershinken, Tim Erdbrügger, Jan‐Ole Radecke, Andreas Sprenger , et al. · 2023

Targeting visual area V5 and frontal eye fields with personalized transcranial direct current stimulation to modulate smooth pursuit eye movements Open

Jan‐Ole Radecke, Andreas Sprenger, Yvonne Buschermöhle, Tim Erdbrügger, Hannah Stöckler , et al. · 2023

Can individually targeted and optimized multi-channel tDCS outperform standard bipolar tDCS in stimulating the primary somatosensory cortex? Open

Asad Khan, Marios Antonakakis, Sonja Suntrup‐Krueger, Rebekka Lencer, Michael A. Nitsche , et al. · 2022

CutFEM forward modeling for EEG source analysis Open

Tim Erdbrügger, Andreas Westhoff, Malte Hoeltershinken, Jan‐Ole Radecke, Yvonne Buschermoehle , et al. · 2022

Source analysis of Electroencephalography (EEG) data requires the computation of the scalp potential induced by current sources in the brain. This so-called EEG forward problem is based on an accurate estimation of the volume conduction ef…

High-Resolution EEG Source Reconstruction with Boundary Element Fast Multipole Method Using Reciprocity Principle and TES Forward Model Matrix Open

William A. Wartman, Tommi Raij, Manas Rachh, Fa‐Hsuan Lin, Konstantin Weise , et al. · 2022

Background Accurate high-resolution EEG source reconstruction (localization) is important for several tasks, including rigorous and rapid mental health screening. Objective The present study has developed, validated, and applied a new sour…

Individually Targeted and Optimized Multi-Channel tDCS Outperforms Standard Bipolar tDCS in Stimulating the Primary Somatosensory Cortex Open

Asad Khan, Marios Antonakakis, Sonja Suntrup-Krüger, Rebekka Lencer, Michael A. Nitsche , et al. · 2022

Validation of EEG forward modeling approaches in the presence of anisotropy in the source space Open

Florian Drechsler, Johannes Vorwerk, Jens Haueisen, Lars Grasedyck, Carsten H. Wolters · 2022

The quality of the inverse approach in electroencephalography (EEG) source analysis is - among other things - depending on the accuracy of the forward modeling approach, i.e., the simulation of the electric potential for a known dipole sou…

Validating EEG, MEG and combined MEG and EEG beamforming for an estimation of the epileptogenic zone in focal cortical dysplasia Open

Frank Neugebauer, Marios Antonakakis, Kanjana Unnwongse, Yaroslav Parpaley, Jörg Wellmer , et al. · 2021

MEG and EEG source analysis is frequently used for the presurgical evaluation of pharma-coresistant epilepsy patients. The source localization of the epileptogenic zone depends, among other aspects, on the selected inverse and forward appr…

Individually optimized multi-channel tDCS for targeting somatosensory cortex Open

Asad Khan, Marios Antonakakis, Nikolas Vogenauer, Jens Haueisen, Carsten H. Wolters · 2021

Carsten H. Wolters YOU? Author Swipe