Carsten Theo Hack
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View article: A Role for H2O2 and TRPM2 in the Induction of Cell Death: Studies in KGN Cells
A Role for H2O2 and TRPM2 in the Induction of Cell Death: Studies in KGN Cells Open
Recent studies showed that KGN cells, derived from a human granulosa cell tumor (GCT), express NADPH oxidase 4 (NOX4), an important source of H2O2. Transient receptor potential melastatin 2 (TRPM2) channel is a Ca2+ permeable cation channe…
View article: The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells
The NADPH oxidase 4 is a major source of hydrogen peroxide in human granulosa-lutein and granulosa tumor cells Open
H 2 O 2 is a reactive oxygen species (ROS), which can diffuse away from its site of generation and may act as a cell-to-cell signaling factor. The mechanisms responsible for the generation of H 2 O 2 in human ovarian follicles and possible…