Explanipedia

COVID-19 Pandemic Exposure and Toddler Behavioral Health in the ECHO Program Open

Anahid Akbaryan, Marie L. Churchill, Monica McGrath, Akram N. Alshawabkeh, Michelle Bosquet Enlow , et al. · 2025

Importance Studies suggest developmental concerns for infants born during the COVID-19 pandemic, but evidence on its impact on toddler behavioral and emotional well-being remains limited. Objective To assess whether birth timing relative t…

The common cold is associated with protection from SARS-CoV-2 Infections Open

Camille M. Moore, E.A. Secor, Jamie L. Everman, Ana Fairbanks-Mahnke, Nathan D. Jackson , et al. · 2025

Background Adults and children often respond differently to SARS-CoV-2 infection, with adults facing a higher risk of symptomatic and severe illness. We hypothesize that children's protection from symptomatic SARS-CoV-2 may be due to more …

Public Water Arsenic and Birth Outcomes in the Environmental Influences on Child Health Outcomes Cohort Open

Anne E. Nigra, Tessa R. Bloomquist, Tushara Rajeev, Mohamad Burjak, Joan A. Casey , et al. · 2025

Importance Inorganic arsenic is associated with adverse birth outcomes, but evidence is limited for public water concentrations (modifiable by federal regulatory action) in US populations. Objective To evaluate the association between pren…

Phenotypes of Atopic Dermatitis and Development of Allergic Diseases Open

Alexandra R. Sitarik, Amy Eapen, Jocelyn M. Biagini Myers, Daniel J. Jackson, Christine L.M. Joseph , et al. · 2025

Importance Atopic dermatitis (AD) is the most common inflammatory disease in childhood, and children with AD are more likely to develop other allergic diseases, including food allergy, allergic rhinitis, and asthma. Objective To determine …

Young adult perspectives on deciding to get human papillomavirus (HPV) vaccination in urban and rural communities: A qualitative research study Open

Maria E. Sundaram, Ben Christianson, Oluwakemi Alonge, Melody Doan, Hanna Ljungman , et al. · 2025

Human papillomavirus (HPV) vaccination coverage in the US is lower than other recommended adolescent vaccines. Coverage is consistently lower in rural areas, compared to urban areas. Despite this, there exists relatively little evidence on…

Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Age 2 to 18 Years Open

Zhongzheng Niu, Ako Adams Ako, Sarah Dee Geiger, Caitlin G. Howe, Wei Perng , et al. · 2025

Importance Higher blood pressure in early life may signal cardiovascular disease over the life course, but determinants of blood pressure in early life are poorly understood. Objective To examine the association of maternal cardiometabolic…

Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort Open

Michael S. Bloom, Sudhi Upadhyaya, Adaeze W. Nzegwu, Jordan R. Kuiper, Jessie P. Buckley , et al. · 2025

Background Research suggests racial/ethnic disparities in prenatal exposure to endocrine disrupting environmental phenols (EPs) in limited populations. However, no studies have investigated racial/ethnic disparities in prenatal EP exposure…

Associations between a novel measure of sleep health and cognitive functioning in middle childhood: a crosssectional Environmental Influences on Child Health Outcomes cohort study Open

J.N. Marchant, Matthew Ferrell, Yingjia Wei, Kelly Glazer Baron, Courtney K. Blackwell , et al. · 2025

Study Objectives Research linking children’s sleep to cognitive outcomes is inconsistent and has largely focused on one aspect of sleep, such as duration, rather than measuring multiple dimensions of sleep health. We hypothesized that chil…

Caregiver worry about COVID-19 as a predictor of social mitigation behaviours and SARS-CoV-2 infection in a 12-city U.S. surveillance study of households with children Open

Steven M. Brunwasser, Tebeb Gebretsadik, Anisha Satish, Jennifer C. Cole, William D. Dupont , et al. · 2024

This was, to our knowledge, the first study showing that caregiver COVID-19 illness worry was predictive of both COVID-19 mitigation compliance and laboratory-determined household infection. Findings should inform studies weighing the adap…

Prenatal Diet and Infant Growth From Birth to Age 24 Months Open

Monique M. Hedderson, Holly B. Schuh, Emily A. Knapp, Traci A. Bekelman, Diane Catellier , et al. · 2024

Importance Being born either small for gestational age (SGA) or large for gestational age (LGA) and experiencing rapid or slow growth after birth are associated with later-life obesity. Understanding the associations of dietary quality dur…

Farm exposure is associated with human breast milk immune profile and microbiome Open

Mary Hannah Swaney, Olivia Steidl, Anastasia Tackett, Samantha Fye, Kristine E. Lee , et al. · 2024

SUMMARY Prenatal and early life farm exposure, and breastfeeding, are associated with protection from allergic diseases. We hypothesize that farm exposure influences the human breast milk microbiome and immune proteins. The immune protein …

Do small effects matter more in vulnerable populations? an investigation using Environmental influences on Child Health Outcomes (ECHO) cohorts Open

Janet L. Peacock, Susana Diaz Coto, Judy R. Rees, Odile Sauzet, Elizabeth T. Jensen , et al. · 2024

Vulnerable sub-populations with greater baseline percentages at high risk fare worse when exposed to a small insult compared to the general population. This illustrates another facet of health disparity in vulnerable individuals.

Association of maternal fish consumption and ω-3 supplement use during pregnancy with child autism-related outcomes: results from a cohort consortium analysis Open

Kristen Lyall, Matt Westlake, Rashelle J. Musci, Kennedy Gachigi, Emily S. Barrett , et al. · 2024

Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort Consortium Open

Kimberly S. McKee, Christine M. Bassis, Jonathan L. Golob, Beatrice Palazzolo, Ananda Sen , et al. · 2024

Human Epidemiology and Response to SARS-CoV-2 (HEROS): objectives, design, and enrollment results of a 12-city remote observational surveillance study of households with children, using direct-to-participant methods Open

Patricia C. Fulkerson, Stephanie Lussier, Casper G. Bendixsen, Sharon Castina, Tebeb Gebretsadik , et al. · 2024

The Human Epidemiology and Response to SARS-CoV-2 (HEROS) Study is a prospective, multicity, 6-month incidence study conducted from May 2020 to February 2021. The objectives were to identify risk factors for SARS-CoV-2 infection and househ…

Risk evaluations of child-livestock interactions by dairy farm parents Open

Jakob Hanschu, Casper G. Bendixsen, Kyle Koshalek, Ryan T. Klataske, Trevor J. Durbin · 2024

The goal of this article is to describe the results of interviews with twenty-five parents of children living and working on dairy farms. The interviews sought to uncover farm parent perspectives and experiences pertaining to raising a kid…

Longitudinal dynamics of farmer and livestock nasal and faecal microbiomes and resistomes Open

Bejan Mahmud, Rhiannon C. Vargas, Kimberley V. Sukhum, Sanket Patel, James Liao , et al. · 2024

Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study Open

Izzuddin M. Aris, Pi‐I D. Lin, Allison J. Wu, Dana Dabelea, Barry M. Lester , et al. · 2024

Farm animal exposure, respiratory illnesses, and nasal cell gene expression Open

Joshua Brownell, Kristine E. Lee, Deborah Chasman, Ronald E. Gangnon, Casper G. Bendixsen , et al. · 2024

Urban and rural healthcare providers’ perspectives on HPV vaccination in Minnesota Open

Elizabeth J. Polter, Ben Christianson, Anne Steinberg, Melody Doan, Hanna Ljungman , et al. · 2023

Human papillomavirus (HPV) vaccination can dramatically reduce the incidence of HPV-associated cancers. However, HPV vaccination coverage in rural areas is lower than in urban areas, and overall HPV vaccination coverage in the United State…

The Big Lie: discursive risk analysis and wildland firefighter safety in the Western United States Open

Trevor J. Durbin, Casper G. Bendixsen, Amber A Neely, Sarah Strauß · 2023

While increased length and intensity of wildfire seasons in many places have led to more concern about wildland firefighter safety, we believe ethnography has been underutilized as a method within this domain. In response, we begin buildin…

Neighborhood Opportunity and Vulnerability and Incident Asthma Among Children Open

Izzuddin M. Aris, Wei Perng, Dana Dabelea, Amy Padula, Akram N. Alshawabkeh , et al. · 2023

Background The extent to which physical and social attributes of neighborhoods play a role in childhood asthma remains understudied. Objective To examine associations of neighborhood-level opportunity and social vulnerability measures with…

Sociodemographic Differences in COVID-19 Pandemic Experiences Among Families in the United States Open

Kaja Z. LeWinn, Leonardo Trasande, Andrew Law, Courtney K. Blackwell, Traci A. Bekelman , et al. · 2023

Importance Few population-based studies in the US collected individual-level data from families during the COVID-19 pandemic. Objective To examine differences in COVID-19 pandemic–related experiences in a large sociodemographically diverse…

Editorial: Safeguarding youth from agricultural injury and illness: international experiences Open

Barbara C. Lee, Florence Becot, Casper G. Bendixsen, Christopher P. Benny, Peter Lundqvist , et al. · 2023

EDITORIAL article Front. Public Health, 18 August 2023Sec. Children and Health Volume 11 - 2023 | https://doi.org/10.3389/fpubh.2023.1270578

Associations between area-level arsenic exposure and adverse birth outcomes: An Echo-wide cohort analysis Open

Jonathan V. Lewis, Emily A. Knapp, Shivani Bakre, Aisha S. Dickerson, Theresa M. Bastain , et al. · 2023

Developing a National-Scale Exposure Index for Combined Environmental Hazards and Social Stressors and Applications to the Environmental Influences on Child Health Outcomes (ECHO) Cohort Open

Sheena E. Martenies, Mingyu Zhang, Anne E. Corrigan, Anton Kvit, Timothy Shields , et al. · 2023

Tools for assessing multiple exposures across several domains (e.g., physical, chemical, and social) are of growing importance in social and environmental epidemiology because of their value in uncovering disparities and their impact on he…

Dairy Farm Work and Protection from Gastrointestinal Illness Open

Jeffrey J. VanWormer, Casper G. Bendixsen, Sanjay K. Shukla · 2023

Gastrointestinal (GI) disorders are a major public health burden in the United States. Due to close contact with animals, farmers may be a high risk subgroup for acute GI infections, though some studies suggest farm work is actually protec…

Health Care Utilization During the COVID-19 Pandemic Among Individuals Born Preterm Open

Elisabeth C. McGowan, Monica McGrath, Andrew Law, T. Michael O’Shea, Judy L. Aschner , et al. · 2023

Importance Limited data exist on pediatric health care utilization during the COVID-19 pandemic among children and young adults born preterm. Objective To investigate differences in health care use related to COVID-19 concerns during the p…

Incidence rates of childhood asthma with recurrent exacerbations in the US Environmental influences on Child Health Outcomes (ECHO) program Open

Rachel L. Miller, Holly B. Schuh, Aruna Chandran, Izzuddin M. Aris, Casper G. Bendixsen , et al. · 2023

The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Open

Emily A. Knapp, Amii Kress, Corette B. Parker, Grier P. Page, Kristen McArthur , et al. · 2023

The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of Health (NIH) in 2016 to improve children’…

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