Cassandra Hong
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View article: Performance of Risk‐Stratification Scores for Patients With Pulmonary Arterial Hypertension in a Multi‐Ethnic Asian Population
Performance of Risk‐Stratification Scores for Patients With Pulmonary Arterial Hypertension in a Multi‐Ethnic Asian Population Open
Guidelines recommend risk stratification of pulmonary arterial hypertension (PAH) patients to guide management. There are currently several risk stratification scores available, which have largely been validated in various pulmonary hypert…
View article: Predictive factors for interstitial lung disease progression in a Singapore systemic sclerosis cohort: a multicentre study
Predictive factors for interstitial lung disease progression in a Singapore systemic sclerosis cohort: a multicentre study Open
Introduction: Interstitial lung disease (ILD) in systemic sclerosis (SSc) is heterogeneous with varied progression rate. This study aimed to identify the baseline clinical characteristics associated with ILD progression within 1, 3 and 5 y…
View article: Validation of the OPTICS and H2FPEF risk scores for post-capillary pulmonary hypertension in an asian cohort
Validation of the OPTICS and H2FPEF risk scores for post-capillary pulmonary hypertension in an asian cohort Open
Background The differentiation between pre- and post-capillary pulmonary hypertension (PH) plays a significant impact in the management of PH patients. Right heart catheterization (RHC) serves as an important test to facilitate this differ…
View article: An innovative hybrid training method for ultrasound in giant cell arteritis, polymyalgia rheumatica and large vessel vasculitis
An innovative hybrid training method for ultrasound in giant cell arteritis, polymyalgia rheumatica and large vessel vasculitis Open
To circumvent the lack of hands-on ultrasound training resulting from inability to conduct face-to-face workshops during the COVID-19 pandemic, especially as local expertise was not available, we developed a novel hybrid method combining v…
View article: Real-world outcomes of Selexipag for treatment of pulmonary hypertension in an Asian population
Real-world outcomes of Selexipag for treatment of pulmonary hypertension in an Asian population Open
Funding Acknowledgements Type of funding sources: None. Introduction Selexipag is an oral selective prostacyclin IP receptor agonist indicated for treatment of pulmonary arterial hypertension (PAH). Data on its real-world safety and effica…
View article: Nailfold capillaroscopy for the early diagnosis of the scleroderma spectrum of diseases in patients without Raynaud’s phenomenon
Nailfold capillaroscopy for the early diagnosis of the scleroderma spectrum of diseases in patients without Raynaud’s phenomenon Open
Background: The utility of nailfold capillaroscopy in the evaluation of patients without Raynaud’s phenomenon is unclear. Objective: This study aims to compare the utility of nailfold capillaroscopy for the early diagnosis of the scleroder…
View article: Intravenous epoprostenol therapy in the treatment of pulmonary arterial hypertension: the Singapore experience
Intravenous epoprostenol therapy in the treatment of pulmonary arterial hypertension: the Singapore experience Open
Funding Acknowledgements Type of funding sources: None. Background Pulmonary arterial hypertension (PAH) is a progressive disease with significant morbidity and mortality. While intravenous (IV) Epoprostenol, a prostacyclin analogue, has b…
View article: Diabetes mellitus is not a risk factor for osteoarthritis
Diabetes mellitus is not a risk factor for osteoarthritis Open
Background Association between diabetes mellitus (DM) and risk of osteoarthritis (OA) can be confounded by body mass index (BMI), a strong risk factor for both conditions. We evaluate the association between DM or hyperglycaemia with OA us…
View article: Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort
Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort Open
PAH is an independent risk factor of mortality in SSc. Increased hospitalization rate was not associated with SSc groups. Other factors associated with increased mortality and hospital admissions were identified.
View article: Pachydermoperiostosis: The Elephant Skin Disease
Pachydermoperiostosis: The Elephant Skin Disease Open
Pachydermoperiostosis (PDP) was first described in 1868. Three forms have been identified: complete (clubbing, periostosis, pachyderma, and cutis verticis gyrata), incomplete (without cutis verticis gyrata), and forme fruste (pachyderma wi…