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  4. Cassandra R. O’Lenick

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View article: Elevated exposure to air pollutants accelerates primary glomerular disease progression
Elevated exposure to air pollutants accelerates primary glomerular disease progression Open
Jonathan P. Troost, Abhijit V. Kshirsagar, Lawrence S. Engel, Cassandra R. O’Lenick, William E. Smoyer , et al. · 2025
Air pollution is a global problem and a major contributor to adverse health outcomes in patients of all ages. Most research has focused on the adverse effects of air pollution on cardiopulmonary events such as myocardial infarction, stroke…
View article: Impact of Heat on Respiratory Hospitalizations among Older Adults in 120 Large U.S. Urban Areas
Impact of Heat on Respiratory Hospitalizations among Older Adults in 120 Large U.S. Urban Areas Open
Cassandra R. O’Lenick, Stephanie E. Cleland, Lucas Neas, Mallory Turner, E. Melissa Mcinroe , et al. · 2024
Rationale: Extreme heat exposure is a well-known cause of mortality among older adults. However, the impacts of exposure on respiratory morbidity across U.S. cities and population subgroups are not well understood. Objectives:
View article: Sociodemographic Determinants of Extreme Heat and Ozone Risk Among Older Adults in 3 Sun Belt Cities
Sociodemographic Determinants of Extreme Heat and Ozone Risk Among Older Adults in 3 Sun Belt Cities Open
Peter J. Crank, Cassandra R. O’Lenick, Amir Baniassadi, David J. Sailor, Olga Wilhelmi , et al. · 2024
BACKGROUND: Vulnerable populations across the United States are frequently exposed to extreme heat, which is becoming more intense due to a combination of climate change and urban-induced warming. Extreme heat can be particularly detriment…
View article: Gestational and postnatal exposure to wildfire smoke and prolonged use of respiratory medications in early life
Gestational and postnatal exposure to wildfire smoke and prolonged use of respiratory medications in early life Open
Hanna V. Jardel, Kristen M. Rappazzo, Thomas J. Luben, Corinna Keeler, Brooke S. Staley , et al. · 2024
As wildfire frequency and severity increases, smoke exposures will cause increasingly more adverse respiratory effects. While acute respiratory effects of smoke exposure have been documented in children, longer term sequelae are largely un…
View article: Characterizing Vulnerability for the Future Heat-Related Cardiovascular Morbidity Burden in U.S. Metropolitan Areas
Characterizing Vulnerability for the Future Heat-Related Cardiovascular Morbidity Burden in U.S. Metropolitan Areas Open
Wei-Lun Tsai, Melissa Mcinroe, Stephanie E. Cleland, Cassandra R. O’Lenick, Mallory Turner , et al. · 2024
View article: Sociodemographic Determinants of Extreme Heat and Ozone Risk Among Older Adults in 3 Sun Belt Cities
Sociodemographic Determinants of Extreme Heat and Ozone Risk Among Older Adults in 3 Sun Belt Cities Open
Peter J. Crank, Cassandra R. O’Lenick, Amir Baniassadi, David J. Sailor, Olga Wilhelmi , et al. · 2024
Background Vulnerable populations across the United States are frequently exposed to extreme heat, which is becoming more intense due to a combination of climate change and urban-induced warming. Extreme heat can be particularly detrimenta…
View article: Impact of heat on respiratory hospitalizations among older adults living in 120 large US urban areas
Impact of heat on respiratory hospitalizations among older adults living in 120 large US urban areas Open
Cassandra R. O’Lenick, Stephanie E. Cleland, Lucas Neas, Mallory Turner, E. Melissa Mcinroe , et al. · 2024
Objectives A nationwide study of the impact of high temperature on respiratory disease hospitalizations among older adults (65+) living in large urban centers. Methods Daily rates of short-stay, inpatient respiratory hospitalizations were …
View article: Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression
Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression Open
Jonathan P. Troost, Jennifer D’Souza, Miatta A. Buxton, Abhijit V. Kshirsagar, Lawrence S. Engel , et al. · 2024
View article: Geographical variation in the impact of extreme heat events on respiratory hospitalizations among older adults in 120 U.S. metropolitan areas
Geographical variation in the impact of extreme heat events on respiratory hospitalizations among older adults in 120 U.S. metropolitan areas Open
Cassandra R. O’Lenick, Mallory Turner, William Steinhardt, Stephanie E. Cleland, Lloyd Hill , et al. · 2023
BACKGROUND AND AIM: Extreme heat exposure is a well-known cause of mortality, particularly among older adults. However, evidence of the effect of extreme heat on morbidity is inconsistent. We applied a uniform modeling approach across 120 …
View article: Connecting physical and social science datasets: challenges and pathways forward
Connecting physical and social science datasets: challenges and pathways forward Open
Sameer H. Shah, Cassandra R. O’Lenick, Jessica Wan, Alexandra Ramos Valle, Kevin D. Ash , et al. · 2023
The integration of physical and social science data can enable novel frameworks, methodologies, and innovative solutions important for addressing complex socio-environmental problems. Unfortunately, many technical, procedural, and institut…
View article: Trends in health and agriculture-relevant ozone metrics over the United States from WRF-CMAQ reanalysis simulations
Trends in health and agriculture-relevant ozone metrics over the United States from WRF-CMAQ reanalysis simulations Open
Forrest Lacey, Rajesh Kumar, Cenlin He, Jennifer Boenhert, Cassandra R. O’Lenick , et al. · 2023
Ozone concentrations have resulted in significant impacts on both human health and crop production throughout the beginning of the 21st century. Results presented here are from a NASA funded WRF-CMAQ model run at a 12km x 12km gridded hori…
View article: Geographic and demographic variation in worry about extreme heat and COVID-19 risk in summer 2020
Geographic and demographic variation in worry about extreme heat and COVID-19 risk in summer 2020 Open
Peter D. Howe, Olga Wilhelmi, Mary H. Hayden, Cassandra R. O’Lenick · 2023
View article: Advancing Interdisciplinary and Convergent Science for Communities: Lessons Learned through the NCAR Early-Career Faculty Innovator Program
Advancing Interdisciplinary and Convergent Science for Communities: Lessons Learned through the NCAR Early-Career Faculty Innovator Program Open
Anamaria Bukvic, Kyle T. Mandli, Donovan Finn, Talea Mayo, Gabrielle Wong‐Parodi , et al. · 2022
The authors introduce the National Center for Atmospheric Research’s Early-Career Faculty Innovator Program and present lessons learned about advancing interdisciplinary and convergent science with and for society. The Innovator Program br…
View article: Moving from interdisciplinary to convergent research across geoscience and social sciences: challenges and strategies
Moving from interdisciplinary to convergent research across geoscience and social sciences: challenges and strategies Open
Donovan Finn, Kyle T. Mandli, Anamaria Bukvic, Christopher A. Davis, Rebecca Haacker , et al. · 2022
View article: Compounding hazards and intersecting vulnerabilities: experiences and responses to extreme heat during COVID-19
Compounding hazards and intersecting vulnerabilities: experiences and responses to extreme heat during COVID-19 Open
Olga Wilhelmi, Peter D. Howe, Mary H. Hayden, Cassandra R. O’Lenick · 2021
Extreme heat is a major threat to human health worldwide. The COVID-19 pandemic, with its complexity and global reach, created unprecedented challenges for public health and highlighted societal vulnerability to hazardous hot weather. In t…
View article: A Case-Crossover Analysis of Indoor Heat Exposure on Mortality and Hospitalizations among the Elderly in Houston, Texas
A Case-Crossover Analysis of Indoor Heat Exposure on Mortality and Hospitalizations among the Elderly in Houston, Texas Open
Cassandra R. O’Lenick, Amir Baniassadi, Ryan Michael, Andrew J. Monaghan, Jennifer Boehnert , et al. · 2020
In locations with high air conditioning prevalence, simplified modeling approaches may adequately account for indoor heat exposure in vulnerable neighborhoods. Accounting for indoor heat exposure may improve the estimation of the total imp…
View article: A case-crossover analysis of indoor heat exposure on mortality and hospitalizations among the elderly in Houston, Texas
A case-crossover analysis of indoor heat exposure on mortality and hospitalizations among the elderly in Houston, Texas Open
Cassandra R. O’Lenick, Amir Baniassadi, R Michael, Andrew J. Monaghan, Jennifer Boehnert , et al. · 2019
TPS 664: Climate change: temperature effects 2, Exhibition Hall, Ground floor, August 27, 2019, 3:00 PM - 4:30 PM Background. Despite the substantial role indoor heat exposure has played in temperature-related mortality, few epidemiologica…
View article: Effects of in vitro Exposure of Human Respiratory Epithelial Cells to Formaldehyde
Effects of in vitro Exposure of Human Respiratory Epithelial Cells to Formaldehyde Open
Cassandra R. O’Lenick · 2019
Formaldehyde is the most abundant carbonyl in air. As a by-product of combustion and other natural processes, it is ubiquitous in the environment. Typically, the formaldehyde concentration levels in ambient air are produced by the photoche…
View article: The growing threat of heat disasters
The growing threat of heat disasters Open
David J. Sailor, Amir Baniassadi, Cassandra R. O’Lenick, Olga Wilhelmi · 2019
Heat is the number one weather-related killer in the United States and indoor exposure is responsible for a significant portion of the resulting fatalities. Evolving construction practices combined with urban development in harsh climates …
View article: Detection and analysis of endogenous polar volatile organic compounds (PVOCs) in urine for human exposome research
Detection and analysis of endogenous polar volatile organic compounds (PVOCs) in urine for human exposome research Open
Cassandra R. O’Lenick, Joachim D. Pleil, Matthew A. Stiegel, Jon R. Sobus, M. Ariel Geer Wallace · 2018
Background: The human exposome, defined as ‘…everything that is not the genome’, comprises all chemicals in the body interacting with life processes. The exposome drives genes x environment (GxE) interactions that can cause l…
View article: Indoor air quality and thermal comfort for elderly residents in Houston TX—a case study
Indoor air quality and thermal comfort for elderly residents in Houston TX—a case study Open
Amir Baniassadi, David J. Sailor, Cassandra R. O’Lenick · 2018
The elderly population is more vulnerable to poor indoor environmental quality. They also spend a larger portion of their time indoors than the general public, further exacerbating the associated health risks. As part of a larger study whi…
View article: Susceptibility to Heat-Related Fluid and Electrolyte Imbalance Emergency Department Visits in Atlanta, Georgia, USA
Susceptibility to Heat-Related Fluid and Electrolyte Imbalance Emergency Department Visits in Atlanta, Georgia, USA Open
Leila Heidari, Andrea Winquist, Mitchel Klein, Cassandra R. O’Lenick, Andrew Grundstein , et al. · 2016
Identification of populations susceptible to heat effects is critical for targeted prevention and more accurate risk assessment. Fluid and electrolyte imbalance (FEI) may provide an objective indicator of heat morbidity. Data on daily ambi…




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