Catherine E. Welsh
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View article: Somatic mtDNA mutations at intermediate levels of heteroplasmy are a source of functional heterogeneity among primary leukemic cells
Somatic mtDNA mutations at intermediate levels of heteroplasmy are a source of functional heterogeneity among primary leukemic cells Open
Somatic mitochondrial DNA (mtDNA) mutations are frequently observed in tumors, yet their role in pediatric cancers remains poorly understood. The heteroplasmic nature of mtDNA—where mutant and wild-type mtDNA coexist—complicates efforts to…
View article: Somatic mitochondrial DNA mutations are a source of heterogeneity among primary leukemic cells
Somatic mitochondrial DNA mutations are a source of heterogeneity among primary leukemic cells Open
Somatic mitochondrial DNA (mtDNA) mutations are prevalent in tumors, yet defining their biological significance remains challenging due to the intricate interplay between selective pressure, heteroplasmy, and cell state. Utilizing bulk who…
View article: The Association of Mitochondrial Copy Number With Sarcopenia in Adult Survivors of Childhood Cancer
The Association of Mitochondrial Copy Number With Sarcopenia in Adult Survivors of Childhood Cancer Open
Background Adult childhood cancer survivors are at risk for frailty, including low muscle mass and weakness (sarcopenia). Using peripheral blood mitochondrial DNA copy number (mtDNAcn) as a proxy for functional mitochondria, this study des…
View article: The Mouse Universal Genotyping Array: From Substrains to Subspecies
The Mouse Universal Genotyping Array: From Substrains to Subspecies Open
Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks. We have developed the third generation of the Mouse Universal Genotyping Array (MUGA) …
View article: The Mouse Universal Genotyping Array: From Substrains to Subspecies
The Mouse Universal Genotyping Array: From Substrains to Subspecies Open
Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks. We have developed the third generation of the Mouse Universal Genotyping Array (MUGA) …
View article: Data from: The mouse universal genotyping array: from substrains to subspecies
Data from: The mouse universal genotyping array: from substrains to subspecies Open
Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks. We have developed the third generation of the Mouse Universal Genotyping Array (MUGA) …
View article: Informatics resources for the Collaborative Cross and related mouse populations
Informatics resources for the Collaborative Cross and related mouse populations Open
View article: Erratum: Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance
Erratum: Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance Open
View article: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance
Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance Open
View article: Informatics resources for the Collaborative Cross and related mouse populations
Informatics resources for the Collaborative Cross and related mouse populations Open