Catherine Hambly
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View article: Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation
Physical activity is directly associated with total energy expenditure without evidence of constraint or compensation Open
The prevailing linear model of physical activity (PA) and total energy expenditure (TEE) has been challenged by models that predict an upper limit of TEE linked to a compensatory reduction elsewhere in the energy budget in response to incr…
View article: The Physiology of the WEight-Reduced State (POWERS) study: environmental, psychological, and social determinants of health
The Physiology of the WEight-Reduced State (POWERS) study: environmental, psychological, and social determinants of health Open
Intentional weight loss is often followed by unintentional weight regain. The causes of weight regain are uncertain but may include a myriad of responses that result in increased hunger and decreased energy expenditure. An individual's psy…
View article: Effects of graded calorie restriction: XXII. Impact of long-term graded calorie restriction on tissue partitioning, digestive efficiency, bone health, and coordination in male C57BL/6J mice
Effects of graded calorie restriction: XXII. Impact of long-term graded calorie restriction on tissue partitioning, digestive efficiency, bone health, and coordination in male C57BL/6J mice Open
Calorie restriction (CR) is the reduction in calorie intake while avoiding malnutrition. CR increases longevity and attenuates the development of many age-related diseases, although some unfavorable responses have been reported. In respons…
View article: Energy expenditure and obesity across the economic spectrum
Energy expenditure and obesity across the economic spectrum Open
Global economic development has been associated with an increased prevalence of obesity and related health problems. Increased caloric intake and reduced energy expenditure are both cited as development-related contributors to the obesity …
View article: Doubly Labelled Water Assessment of Elite Male-Squash Player’s Energy Balance During a Seven-Day Training Microcycle
Doubly Labelled Water Assessment of Elite Male-Squash Player’s Energy Balance During a Seven-Day Training Microcycle Open
No previous research has quantified the energy balance of elite male squash players during a training microcycle. Consequently, the aim of this study was to concurrently quantify energy expenditure (EE), energy intake (EI) and energy avail…
View article: Lactation at hot temperature: a test of heat dissipation limitation in mice divergently selected for basal metabolic rate
Lactation at hot temperature: a test of heat dissipation limitation in mice divergently selected for basal metabolic rate Open
The HDL (heat dissipation limitation) hypothesis posits that mammalian energy budgets (SuSMR, sustained metabolic rate) are limited by the ability to dissipate metabolic heat. The HDL hypothesis has been tested in lactating mice but rarely…
View article: Author Correction: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake
Author Correction: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake Open
View article: Extreme heat risk and the potential implications for the scheduling of football matches at the 2026 FIFA World Cup
Extreme heat risk and the potential implications for the scheduling of football matches at the 2026 FIFA World Cup Open
View article: Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake
Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake Open
Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes wit…
View article: The threat of extreme heat to football players and match officials at the 2026 FIFA World Cup
The threat of extreme heat to football players and match officials at the 2026 FIFA World Cup Open
Climate change is making extreme heat events more frequent and intense. This negatively impacts many aspects of society, including organised sport. As the world’s most watched sporting event, the FIFA World Cup commands particular attentio…
View article: Increased Susceptibility of Rousettus aegyptiacus Bats to Respiratory SARS-CoV-2 Challenge Despite Its Distinct Tropism for Gut Epithelia in Bats
Increased Susceptibility of Rousettus aegyptiacus Bats to Respiratory SARS-CoV-2 Challenge Despite Its Distinct Tropism for Gut Epithelia in Bats Open
Increasing evidence suggests bats are the ancestral hosts of the majority of coronaviruses. In general, coronaviruses primarily target the gastrointestinal system, while some strains, especially Betacoronaviruses with the most relevant rep…
View article: Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory
Reproduction has immediate effects on female mortality, but no discernible lasting physiological impacts: A test of the disposable soma theory Open
The disposable soma theory (DST) posits that organisms age and die because of a direct trade-off in resource allocation between reproduction and somatic maintenance. DST predicts that investments in reproduction accentuate somatic damage w…
View article: Evidence for SARS-CoV-2 infected Golden Syrian hamsters (Mesocricetus auratus) reducing daily energy expenditure and body core temperature
Evidence for SARS-CoV-2 infected Golden Syrian hamsters (Mesocricetus auratus) reducing daily energy expenditure and body core temperature Open
View article: Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability?
Energy expenditure, intake and availability in female soccer players via doubly labelled water: Are we misrepresenting low energy availability? Open
Female soccer players have been identified as presenting with low energy availability (LEA), though the prevalence of LEA may be overestimated given inaccuracies associated with self‐reporting dietary intakes. Accordingly, we aimed to quan…
View article: Daily energy expenditure and water turnover in female netball players from the Netball Super League: A doubly labeled water observation study
Daily energy expenditure and water turnover in female netball players from the Netball Super League: A doubly labeled water observation study Open
To establish the criterion‐assessed energy and fluid requirements of female netball players, 13 adult players from a senior Netball Super League squad were assessed over 14 days in a cross‐sectional design, representing a two‐ and one‐matc…
View article: Validity of predictive equations for total energy expenditure against doubly labeled water
Validity of predictive equations for total energy expenditure against doubly labeled water Open
Variations in physical activity energy expenditure can make accurate prediction of total energy expenditure (TEE) challenging. The purpose of the present study was to determine the accuracy of available equations to predict TEE in individu…
View article: Validation of the 2 × 24 h recall method and a 7-d web-based food diary against doubly labelled water in Danish adults – CORRIGENDUM
Validation of the 2 × 24 h recall method and a 7-d web-based food diary against doubly labelled water in Danish adults – CORRIGENDUM Open
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View article: Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction
Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction Open
View article: Not feeling the heat? Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature
Not feeling the heat? Effects of dietary protein on satiation and satiety in mice are not due to its impact on body temperature Open
View article: Links between energy budgets, somatic condition, and life history reveal heterogeneous energy management tactics in a group-living mesocarnivore
Links between energy budgets, somatic condition, and life history reveal heterogeneous energy management tactics in a group-living mesocarnivore Open
View article: Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice
Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice Open
Maternal overnutrition during lactation predisposes offspring to develop metabolic diseases and exacerbates the relevant syndromes in males more than females in later life. The hypothalamus is a heterogenous brain region that regulates ene…
View article: Behavioural variability, physical activity, rumination time, and milk characteristics of dairy cattle in response to regrouping
Behavioural variability, physical activity, rumination time, and milk characteristics of dairy cattle in response to regrouping Open
In the commercial dairy industry worldwide, it is common practice to periodically regroup cows as part of their management strategy within housed systems. While this animal husbandry practice is intended to improve management efficiency, c…
View article: Limits to sustained energy intake. XXXIV. Can the heat dissipation limit (HDL) theory explain reproductive aging?
Limits to sustained energy intake. XXXIV. Can the heat dissipation limit (HDL) theory explain reproductive aging? Open
According to the heat dissipation limit (HDL) theory, reproductive performance is limited by the capacity to dissipate excess heat. We tested the novel hypotheses that (1) the age-related decline in reproductive performance is due to an ag…
View article: Post-restriction hyperphagia and metabolic responses to short-term calorie restriction in C57BL/6 mice
Post-restriction hyperphagia and metabolic responses to short-term calorie restriction in C57BL/6 mice Open
Aims: To evaluate post-restriction hyperphagia (PRH) responses to short-term calorie restriction (CR) and the potential drivers of this behaviour. Methods: Adult male C57BL/6J mice underwent 30% CR for 5 to 30 days, then refed for 12 days.…
View article: Great tits (Parus major) in a west European temperate forest show little seasonal variation in metabolic energy requirements
Great tits (Parus major) in a west European temperate forest show little seasonal variation in metabolic energy requirements Open
View article: Greater male variability in daily energy expenditure develops through puberty
Greater male variability in daily energy expenditure develops through puberty Open
There is considerably greater variation in metabolic rates between men than between women, in terms of basal, activity and total (daily) energy expenditure (EE). One possible explanation is that EE is associated with male sexual characteri…
View article: Validating Dynamic Body Acceleration metrics as a measure of energy expenditure in a Neotropical primate
Validating Dynamic Body Acceleration metrics as a measure of energy expenditure in a Neotropical primate Open
2 A bstract Quantifying energy expenditure in free-living primates is fundamentally important yet challenging. Acceleration-based metrics such as Dynamic Body Acceleration (DBA), obtained from accelerometers, are potential proxies for ener…
View article: The Effects of Graded Levels of Calorie Restriction: XX. Impact of Long-Term Graded Calorie Restriction on Survival and Body Mass Dynamics in Male C57BL/6J Mice
The Effects of Graded Levels of Calorie Restriction: XX. Impact of Long-Term Graded Calorie Restriction on Survival and Body Mass Dynamics in Male C57BL/6J Mice Open
Calorie restriction (CR) typically promotes a reduction in body mass, which correlates with increased lifespan. We evaluated the overall changes in survival, body mass dynamics, and body composition following long-term graded CR (580 days/…
View article: Daily energy requirements of male academy soccer players are greater than age-matched non-academy soccer players: A doubly labelled water investigation
Daily energy requirements of male academy soccer players are greater than age-matched non-academy soccer players: A doubly labelled water investigation Open
This study aimed to test the hypothesis that the total daily energy expenditure (TDEE) of male academy soccer players is greater than players not enrolled on a formalised academy programme. English Premier League academy (ACAD: n = …
View article: Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure
Total daily energy expenditure has declined over the past three decades due to declining basal expenditure, not reduced activity expenditure Open