Chengcheng Han
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View article: Efficacy and safety of neoadjuvant therapy combined with immunotherapy in MMR‑proficient/microsatellite stable non‑metastatic rectal cancer: a systematic review and meta‑analysis
Efficacy and safety of neoadjuvant therapy combined with immunotherapy in MMR‑proficient/microsatellite stable non‑metastatic rectal cancer: a systematic review and meta‑analysis Open
Neoadjuvant therapy combined with immunotherapy in pMMR/MSS non-metastatic rectal cancer demonstrates promising efficacy-with high response rates, excellent R0 resection, and favorable anal preservation outcomes-and an acceptable safety pr…
View article: Assessment of functional decline in stroke patients using 3D deep learning and dynamic functional connectivity based on resting-state fMRI
Assessment of functional decline in stroke patients using 3D deep learning and dynamic functional connectivity based on resting-state fMRI Open
Introduction This study aimed to develop an automated approach for assessing upper limb (UL) motor impairment severity in stroke patients using a deep learning framework applied to resting-state functional magnetic resonance imaging (rs-fM…
View article: Cosmological signatures of neutrino seesaw mechanism
Cosmological signatures of neutrino seesaw mechanism Open
The tiny neutrino masses are most naturally explained by seesaw mechanism through singlet right-handed neutrinos, which can further explain the matter-antimatter asymmetry in the Universe. In this work, we propose a new approach to study c…
View article: Hybrid Type-II and Type-III seesaw model for the muon g − 2 anomaly
Hybrid Type-II and Type-III seesaw model for the muon g − 2 anomaly Open
In this work we investigate the muon anomalous magnetic dipole moment aμ in a model that extends the Standard Model with a scalar triplet and a lepton triplet. Different from previous studies, we find that there is still viable parameter s…
View article: Cosmological non-Gaussianity from the neutrino seesaw mechanism
Cosmological non-Gaussianity from the neutrino seesaw mechanism Open
The neutrino mass generation via conventional seesaw mechanism is realized at high scales around O ( 10 14 ) GeV with natural Yukawa couplings of O ( 1 ) , making the test of the neutrino seesaw a great challenge. It is intriguin…
View article: Probing nonthermal gravitinos through large-scale structure observations
Probing nonthermal gravitinos through large-scale structure observations Open
We investigate the effects of nonthermally produced dark matter on large-scale structure formation, focusing on the gravitino dark matter. Our analysis shows that large-scale structure measurements from the Sloan Digital Sky Survey (SDSS) …
View article: Probing Type II Seesaw Leptogenesis Through Lepton Flavor Violation
Probing Type II Seesaw Leptogenesis Through Lepton Flavor Violation Open
Lepton flavor violation (LFV) offers a powerful probe of physics beyond the Standard Model, particularly in models addressing neutrino masses and the baryon asymmetry of the universe. In this study, we investigate LFV processes within the …
View article: Cosmological Signatures of Neutrino Seesaw Mechanism
Cosmological Signatures of Neutrino Seesaw Mechanism Open
The tiny neutrino masses are most naturally explained by seesaw mechanism through singlet right-handed neutrinos, which can further explain the matter-antimatter asymmetry in the Universe. In this Letter, we propose a new approach to study…
View article: Cosmological Non-Gaussianity from Neutrino Seesaw Mechanism
Cosmological Non-Gaussianity from Neutrino Seesaw Mechanism Open
The neutrino mass generation via conventional seesaw mechanism is realized at high scales around $O(10^{14})$GeV with natural Yukawa couplings of $O(1)$, making the test of neutrino seesaw a great challenge. It is intriguing to note that t…
View article: Endoscopic and imaging evaluations of the primary tumor response in patients with proficient mismatch repair colorectal cancer treated with neoadjuvant combination immunotherapy
Endoscopic and imaging evaluations of the primary tumor response in patients with proficient mismatch repair colorectal cancer treated with neoadjuvant combination immunotherapy Open
Background Neoadjuvant combination immunotherapy is a potential treatment option for patients with proficient mismatch repair/microsatellite stable colorectal cancer. Preoperative screening via endoscopy and imaging exams could help identi…
View article: Hybrid Type-II and Type-III seesaw model for the muon $g-2$ anomaly
Hybrid Type-II and Type-III seesaw model for the muon $g-2$ anomaly Open
In this work we investigate the muon anomalous magnetic dipole moment $a_μ$ in a model that extends the Standard Model with a scalar triplet and a lepton triplet. Different from previous studies, we find that there is still viable paramete…
View article: Probing Non-Thermal Gravitinos Through Large-Scale Structure Observations
Probing Non-Thermal Gravitinos Through Large-Scale Structure Observations Open
We investigate the effects of non-thermally produced dark matter on large-scale structure formation, focusing on the gravitino dark matter. Our analysis shows that large-scale structure measurements from the SDSS LRG data offer a promising…
View article: Self-interacting dark matter implied by nano-Hertz gravitational waves
Self-interacting dark matter implied by nano-Hertz gravitational waves Open
The self-interacting dark matter (SIDM) paradigm offers a potential solution to the small-scale structure problems faced by collisionless cold dark matter. This framework incorporates self-interactions among dark matter particles, typicall…
View article: Affleck-Dine Dirac Leptogenesis
Affleck-Dine Dirac Leptogenesis Open
We present a minimal framework that realises successful Dirac Leptogenesis through the Affleck-Dine mechanism. A single right-handed neutrino and a neutrinophillic Higgs doublet are introduced to the Standard Model, which couple via a Yuka…
View article: Freeze-in bino dark matter in high-scale supersymmetry
Freeze-in bino dark matter in high-scale supersymmetry Open
We explore a scenario of high-scale supersymmetry where all supersymmetric particles except gauginos stay at a high-energy scale MSUSY that is much larger than the reheating temperature TRH. The dark matter is dominated by a bino component…
View article: Type-II Seesaw Leptogenesis along the Ridge
Type-II Seesaw Leptogenesis along the Ridge Open
Type-II seesaw leptogenesis is a model that integrates inflation, baryon number asymmetry, and neutrino mass simultaneously. It employs the Affleck-Dine mechanism to generate lepton asymmetry, with the Higgs bosons serving as the inflaton.…
View article: Freeze-in bino dark matter in high scale supersymmetry
Freeze-in bino dark matter in high scale supersymmetry Open
We explore a scenario of high scale supersymmetry where all supersymmetric particles except gauginos stay at a high energy scale $M_{\rm SUSY}$ which is much larger than the reheating temperature $T_\text{RH}$. The dark matter is dominated…
View article: QCD axion dark matter and the cosmic dipole problem
QCD axion dark matter and the cosmic dipole problem Open
There is increasing evidence suggesting a discrepancy between the cosmic dipole observed in the number count of distant galaxies and the one derived from the cosmic microwave background (CMB). In this study, we investigate the possibility …
View article: Testing type II seesaw leptogenesis at the LHC*
Testing type II seesaw leptogenesis at the LHC* Open
Type II seesaw leptogenesis simultaneously explains the origin of neutrino masses, the baryon asymmetry of our universe, and inflation. The Large Hadron Collider (LHC) provides an opportunity to directly test type II seesaw leptogenesis by…
View article: Self-interacting dark matter implied by nano-Hertz gravitational waves
Self-interacting dark matter implied by nano-Hertz gravitational waves Open
The self-interacting dark matter (SIDM) paradigm offers a potential solution to the small-scale structure problems faced by collision-less cold dark matter. This framework incorporates self-interactions among dark matter particles, typical…
View article: Nanogenerator application: New high-voltage power supplytechnology
Nanogenerator application: New high-voltage power supplytechnology Open
Triboelectric nanogenerators (TENG), as an emerging energy harvesting technology, have made rapid progress over the past decade. In addition to applications such as micro-nano energy and self-driving sensing, the output characteristics of …
View article: Testing type II seesaw leptogenesis at the LHC
Testing type II seesaw leptogenesis at the LHC Open
Type II seesaw leptogenesis simultaneously explains the origin of neutrino masses, the baryon asymmetry of our universe, and the inflation. The Large Hadron Collider(LHC) provides an opportunity to directly test type II seesaw leptogenesis…
View article: Correlation length of the angular mode for an approximate U(1) symmetry during inflation
Correlation length of the angular mode for an approximate U(1) symmetry during inflation Open
It is known that a light scalar field obtains fluctuations in the de Sitter inflationary background. Such fluctuations could provide an initial condition for baryogenesis through the Affleck-Dine mechanism, where an approximate U(1)B symme…
View article: Vacuum stability of the type II seesaw leptogenesis from inflation
Vacuum stability of the type II seesaw leptogenesis from inflation Open
Recently, it has been found that introducing a triplet Higgs to the standard model could provide a feasible leptogenesis to generate the baryon asymmetry of our Universe, providing that the inflation is driven by the mixing state of the tr…
View article: QCD axion dark matter and the cosmic dipole problem
QCD axion dark matter and the cosmic dipole problem Open
There is increasing evidence suggesting a discrepancy between the cosmic dipole observed in the number count of distant galaxies and the one derived from the cosmic microwave background (CMB). In this study, we investigate the possibility …
View article: Vacuum stability of the type II seesaw leptogenesis from inflation
Vacuum stability of the type II seesaw leptogenesis from inflation Open
Recently it has been found that introducing a triplet Higgs to the standard model could provide a feasible leptogenesis to generate the baryon asymmetry of our universe, providing that the inflation is driven by the mixing state of the tri…
View article: Correlation length of the angular mode for an approximate $U(1)$ symmetry during inflation
Correlation length of the angular mode for an approximate $U(1)$ symmetry during inflation Open
It is known that a light scalar field obtains fluctuations in the de Sitter inflationary background. Such fluctuations could provide an initial condition for baryogenesis through the Affleck-Dine mechanism, where an approximate $U(1)_B$ sy…