Lucia Knight
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View article: Informal social support for chronic pain and distress in people with HIV: identifying targets for intervention
Informal social support for chronic pain and distress in people with HIV: identifying targets for intervention Open
Social factors are consequences and determinants of chronic pain, yet little is known about how informal social support operates for people with chronic pain and HIV. The overlapping burdens of emotional distress and chronic pain in people…
View article: “I’ll Continue If I Have a Positive Mind”: Identifying the Ways in Which Depression and PTSD Impact PrEP Adherence Among PrEP-Experienced Pregnant and Postpartum Women in Cape Town, South Africa
“I’ll Continue If I Have a Positive Mind”: Identifying the Ways in Which Depression and PTSD Impact PrEP Adherence Among PrEP-Experienced Pregnant and Postpartum Women in Cape Town, South Africa Open
Pregnant and postpartum people (PPPs) face heightened risk for HIV acquisition, yet depression and trauma-related symptoms can undermine adherence to pre-exposure prophylaxis (PrEP). To inform the development of a brief mental health-focus…
View article: “I became alright after birth”: Mechanisms driving improvements in mental health symptoms in the postpartum transition among persons at risk for HIV in South Africa
“I became alright after birth”: Mechanisms driving improvements in mental health symptoms in the postpartum transition among persons at risk for HIV in South Africa Open
Background: Pregnant and postpartum persons (PPPs) are at increased risk for HIV acquisition, and depression and posttraumatic stress disorder (PTSD) negatively impact engagement in HIV prevention behaviors like pre-exposure prophylaxis (P…
View article: Telemedicine contraceptive counselling through WhatsApp in South African abortion care: a mixed-methods acceptability study
Telemedicine contraceptive counselling through WhatsApp in South African abortion care: a mixed-methods acceptability study Open
This pilot demonstrates high acceptability of PlanUrFam in abortion care and supported informed decision-making and choice of LARC. The effectiveness of PlanUrFam or similar interventions compared to standard care should be explored in ran…
View article: Age‐specific all‐cause mortality rates among adolescents and youth living with and without HIV: Evidence from a cohort study in South Africa
Age‐specific all‐cause mortality rates among adolescents and youth living with and without HIV: Evidence from a cohort study in South Africa Open
Introduction Mortality among adolescents living with HIV (ALHIV) remains a global health problem. We lack granular (age‐ and sex‐disaggregated) data on mortality among ALHIV, hence, this study aims to assess all‐cause mortality among ALHIV…
View article: Intersection of Design and Society: Student and Faculty Reflection on an Interdisciplinary Course
Intersection of Design and Society: Student and Faculty Reflection on an Interdisciplinary Course Open
View article: Routine Electronic Mother-Infant Data (REMInD): A proof-of-Concept Data to Care Study to Support Retention in Maternal HIV Treatment and Infant HIV Testing in Cape Town, South Africa
Routine Electronic Mother-Infant Data (REMInD): A proof-of-Concept Data to Care Study to Support Retention in Maternal HIV Treatment and Infant HIV Testing in Cape Town, South Africa Open
Data to Care (D2C) strategies– using routine data to identify and re-engage people living with HIV who are not in care– have shown promise in high-income settings but remain underexplored in lower-resource and vertical HIV transmission pre…
View article: A qualitative process evaluation of community-based participatory research and human-centered design in the ‘Let’s talk about vaccines’ approach in Mozambique and Malawi
A qualitative process evaluation of community-based participatory research and human-centered design in the ‘Let’s talk about vaccines’ approach in Mozambique and Malawi Open
View article: To what extent are digital health interventions targeting HIV care cascade among mobile populations feasible, acceptable, and effective? A mixed methods systematic review protocol
To what extent are digital health interventions targeting HIV care cascade among mobile populations feasible, acceptable, and effective? A mixed methods systematic review protocol Open
This protocol is registered on PROSPERO (CRD42024528122).
View article: A perspective on essential components for adaptability and scalability to enhance equity-driven vaccination interventions: lessons from Mozambique and Malawi.
A perspective on essential components for adaptability and scalability to enhance equity-driven vaccination interventions: lessons from Mozambique and Malawi. Open
Global threats, including the COVID-19 pandemic, vaccine funding cuts, and persistent health inequities, are reversing decades of hard-won gains in immunisation coverage, particularly access for vulnerable populations. This highlights an u…
View article: Routine Electronic Mother-Infant Data (REMInD): a proof-of-concept Data to Care study to support retention in maternal HIV treatment and infant HIV testing in Cape Town, South Africa
Routine Electronic Mother-Infant Data (REMInD): a proof-of-concept Data to Care study to support retention in maternal HIV treatment and infant HIV testing in Cape Town, South Africa Open
Data to Care (D2C) strategies – using routine data to facilitate identification and linkage back to care of people living with HIV who are not in care – have shown promise in high-income settings but received little attention in lower reso…
View article: Health System Factors Influencing the Integration of Pre-Exposure Prophylaxis into Antenatal and Postnatal Clinic Services in Cape Town, South Africa
Health System Factors Influencing the Integration of Pre-Exposure Prophylaxis into Antenatal and Postnatal Clinic Services in Cape Town, South Africa Open
Facilitators for PrEP integration include task-shifting PrEP education and identification of women for PrEP initiation to HIV counselors, changes to national guidelines defining who can prescribe PrEP, revision and integration of PrEP trai…
View article: Enhancing childhood immunization coverage in Mozambique and Malawi: Study protocol of a mixed methods evaluation of the ‘Let’s talk about vaccines’ multisite community-based participatory project
Enhancing childhood immunization coverage in Mozambique and Malawi: Study protocol of a mixed methods evaluation of the ‘Let’s talk about vaccines’ multisite community-based participatory project Open
Background Full coverage of childhood vaccines is a persistent challenge in low- and middle-income countries, suggesting the presence of specific contextual barriers. The emergence of the COVID-19 pandemic further worsened the situation. T…
View article: Adapting to, integrating and self-managing HIV as a chronic illness: a scoping review
Adapting to, integrating and self-managing HIV as a chronic illness: a scoping review Open
View article: Exploring the effects of mental health on bonding and caregiving among pregnant and postpartum persons with likely depression and/or PTSD in South Africa: A qualitative analysis
Exploring the effects of mental health on bonding and caregiving among pregnant and postpartum persons with likely depression and/or PTSD in South Africa: A qualitative analysis Open
Perinatal mental health disorders place a particularly high public health burden on South Africa (SA) via negative health outcomes for the birthing parent and adverse health outcomes for infants (e.g., low birth weight, preterm deliveries,…
View article: A qualitative process evaluation: Understanding the “Let’s talk about vaccines” approach’s complementary use of community-based participatory research and human- centered design in under two immunization programming
A qualitative process evaluation: Understanding the “Let’s talk about vaccines” approach’s complementary use of community-based participatory research and human- centered design in under two immunization programming Open
Introduction Full coverage of childhood vaccines is a persistent challenge in low- and middle-income countries and there is an urgent need to catch up on children who have missed out on vaccines. This paper summarizes the findings of a pro…
View article: “I managed to stand on my own. I saved my baby’s life.”: qualitative analysis of birth experiences from women living with HIV in Cape Town, South Africa
“I managed to stand on my own. I saved my baby’s life.”: qualitative analysis of birth experiences from women living with HIV in Cape Town, South Africa Open
View article: “I Have to Stand Up on My Own and Do the Best I Can for My Kids”a: Work (Re-)entry Among New Mothers Living with HIV in Cape Town, South Africa
“I Have to Stand Up on My Own and Do the Best I Can for My Kids”a: Work (Re-)entry Among New Mothers Living with HIV in Cape Town, South Africa Open
View article: The HIV prevention decision-making cascade: Integrating behavioural insights into HIV prevention efforts
The HIV prevention decision-making cascade: Integrating behavioural insights into HIV prevention efforts Open
The syndemic of HIV, sexually transmitted infections (STIs), and early pregnancy remain a key challenge to global public health. Decision-making around sexual and reproductive health (SRH) behaviours is critical to ensuring the uptake of b…
View article: Including the Household: Individual, Community and Household Factors Affecting Antiretroviral Therapy Adherence After ART Initiation in Cape Town, South Africa
Including the Household: Individual, Community and Household Factors Affecting Antiretroviral Therapy Adherence After ART Initiation in Cape Town, South Africa Open
Antiretroviral therapy (ART) adherence is crucial for health outcomes of people living with HIV (PLHIV), influenced by a complex interplay of individual, community, and household factors. This article focuses on the influence of household …
View article: Experiences of transfer of care among postpartum women living with HIV attending primary healthcare services in South Africa
Experiences of transfer of care among postpartum women living with HIV attending primary healthcare services in South Africa Open
Transfers between health facilities for postpartum women living with HIV are associated with disengagement from care. In South Africa, women must transfer from integrated antenatal/HIV care to general HIV services post-delivery. Thereafter…
View article: Longitudinal Trajectories of Antiretroviral Treatment Adherence and Associations With Durable Viral Suppression Among Adolescents Living With HIV in South Africa
Longitudinal Trajectories of Antiretroviral Treatment Adherence and Associations With Durable Viral Suppression Among Adolescents Living With HIV in South Africa Open
Background: Compared with other age groups, adolescents living with HIV (ALHIV) are estimated to have lower levels of adherence to antiretroviral treatment. Despite this, we lack evidence on adolescents' adherence patterns over time to inf…
View article: A cross-cultural adaptation and validation of a scale to assess Illness Identity in adults living with a chronic illness in South Africa- a case of HIV
A cross-cultural adaptation and validation of a scale to assess Illness Identity in adults living with a chronic illness in South Africa- a case of HIV Open
The chronic illness trajectory and its outcomes are well explained by the concept of illness identity; the extent to which ill individuals have integrated their diagnosed chronic illness into their identity or sense of self. The capacity t…
View article: Exploring perceptions of gender roles amongst sexually active adolescents in rural KwaZulu-Natal, South Africa
Exploring perceptions of gender roles amongst sexually active adolescents in rural KwaZulu-Natal, South Africa Open
Traditional gender and social norms reinforce asymmetrical power relations, increase the risk of experiencing gender-based violence and mediate poor engagement with sexual and reproductive health services. This study explored gender norms …
View article: Experiences of alcohol use during pregnancy: A qualitative study of pregnant women at risk of acquiring HIV in Cape Town, South Africa
Experiences of alcohol use during pregnancy: A qualitative study of pregnant women at risk of acquiring HIV in Cape Town, South Africa Open
In South Africa, alcohol use during pregnancy is prevalent and associated with increased HIV risk. Developing locally sensitive and contextually appropriate evidence-based interventions to address alcohol use among pregnant and breastfeedi…
View article: Womandla Health: development and rationale of a behavioral intervention to support HIV treatment adherence among postpartum women in South Africa
Womandla Health: development and rationale of a behavioral intervention to support HIV treatment adherence among postpartum women in South Africa Open
Background While Option B + has made great strides in eliminating vertical transmission of HIV and improving access to lifelong antiretroviral therapy (ART) for women, the postpartum period remains a risk period for disengagement from HIV …
View article: Study Protocol: Evaluation of a multisite community-based participatory project to achieve full childhood immunization coverage in Mozambique and Malawi (Let’s talk about vaccines project)
Study Protocol: Evaluation of a multisite community-based participatory project to achieve full childhood immunization coverage in Mozambique and Malawi (Let’s talk about vaccines project) Open
Background Full coverage of childhood vaccines is a persistent challenge in low- and middle-income countries, with the emergence of the COVID-19 pandemic further worsening the situation. The complementary use of community-based participato…
View article: Study Protocol for a type 2 hybrid effectiveness-implementation evaluation of a multisite community-based participatory project to achieve full childhood immunization coverage in Mozambique and Malawi (Let’s talk about vaccines project)
Study Protocol for a type 2 hybrid effectiveness-implementation evaluation of a multisite community-based participatory project to achieve full childhood immunization coverage in Mozambique and Malawi (Let’s talk about vaccines project) Open
Background Full coverage of childhood vaccines is a persistent challenge in low- and middle-income countries, with the emergence of the COVID-19 pandemic further worsening the situation. The complementary use of community-based participato…
View article: “Words are too small”: exploring artmaking as a tool to facilitate dialogues with young South African women about their sexual and reproductive health experiences
“Words are too small”: exploring artmaking as a tool to facilitate dialogues with young South African women about their sexual and reproductive health experiences Open
Background Adolescents and young women are at high risk for sexually transmitted infections (STIs) and unintended pregnancies. However, conversations about sexual and reproductive health (S&RH) are difficult and stigmatised. Visual art…
View article: Exploring Self-reported Adherence Measures to Screen for Elevated HIV Viral Load in Adolescents: A South African Cohort Study
Exploring Self-reported Adherence Measures to Screen for Elevated HIV Viral Load in Adolescents: A South African Cohort Study Open
The timely identification of ART non-adherence among adolescents living with HIV presents a significant challenge, particularly in resource-limited settings where virologic monitoring is suboptimal. Using South African adolescent cohort da…