Cathy Lu
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View article: ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with Inflammatory Bowel Disease: Part 2
ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with Inflammatory Bowel Disease: Part 2 Open
View article: Diagnostic Accuracy of Noninvasive Biomarkers and Imaging for Evaluating Postoperative Recurrence in Crohn’s Disease
Diagnostic Accuracy of Noninvasive Biomarkers and Imaging for Evaluating Postoperative Recurrence in Crohn’s Disease Open
The high sensitivity of fecal calprotectin (<50 μg/g) and cross-sectional imaging can help reduce the need for invasive and costly colonoscopy monitoring for CD recurrence after surgery. Applying optimal definitions of sonographic recurren…
View article: A220 LONG-TERM EFFECTIVENESS AND SAFETY OF USTEKINUMAB DOSE ESCALATION IN PATIENTS WITH REFRACTORY ULCERATIVE COLITIS: A MULTICENTER RETROSPECTIVE COHORT STUDY
A220 LONG-TERM EFFECTIVENESS AND SAFETY OF USTEKINUMAB DOSE ESCALATION IN PATIENTS WITH REFRACTORY ULCERATIVE COLITIS: A MULTICENTER RETROSPECTIVE COHORT STUDY Open
Background Ustekinumab dose escalation (DE) may be an effective strategy to recapture clinical response in patients with ulcerative colitis (UC). Aims The aim of this study was to assess the real-world long-term effectiveness and safety of…
View article: A7 THERAPEUTIC DIETARY INTERVENTION IN ADULT CROHN’S DISEASE PATIENTS: EFFECTS ON REMISSION MARKERS, QUALITY OF LIFE, AND PHYSICAL ACTIVITY
A7 THERAPEUTIC DIETARY INTERVENTION IN ADULT CROHN’S DISEASE PATIENTS: EFFECTS ON REMISSION MARKERS, QUALITY OF LIFE, AND PHYSICAL ACTIVITY Open
Background Current evidence recognizes diet and physical activity as important factors in influencing the natural history of Crohn’s disease (CD); however, the relationship between dietary components and disease relapse remains unclear. Pa…
View article: A221 GENERALIZABILITY OF RANDOMIZED CONTROLLED TRIALS TO ROUTINE CLINICAL CARE IN ULCERATIVE COLITIS
A221 GENERALIZABILITY OF RANDOMIZED CONTROLLED TRIALS TO ROUTINE CLINICAL CARE IN ULCERATIVE COLITIS Open
Background Historically, randomized controlled trials (RCTs) have been criticized for being poorly generalizable to patients with ulcerative colitis (UC) evaluated in routine care. Aims We aimed to evaluate the proportion of patients with …
View article: Generalizability of Randomized Controlled Trials to Routine Clinical Care in Ulcerative Colitis
Generalizability of Randomized Controlled Trials to Routine Clinical Care in Ulcerative Colitis Open
Background Historically, randomized controlled trials (RCTs) have been criticized for being poorly generalizable to patients with ulcerative colitis (UC) evaluated in routine care. We aimed to evaluate the proportion of patients with UC st…
View article: Latest Intestinal Ultrasound Advancements In Inflammatory Bowel Disease
Latest Intestinal Ultrasound Advancements In Inflammatory Bowel Disease Open
Inflammatory bowel disease (IBD) treatment has evolved from monitoring clinical symptoms to targeting objective measurements of mucosal healing with endoscopic and radiologic imaging. It is well known that clinical symptoms do not match di…
View article: A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease in clinical practice
A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease in clinical practice Open
View article: Systematic review: Defining, diagnosing and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound
Systematic review: Defining, diagnosing and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound Open
Summary Background Stricturing Crohn's disease (CD) occurs most commonly in the terminal ileum and poses a clinical problem. Cross‐sectional imaging modalities such as intestinal ultrasound (IUS), computed tomography enterography (CTE), an…
View article: A220 MORTALITY IN PATIENTS WITH ULCERATIVE COLITIS UNDERGOING COLECTOMY (2016-2020)
A220 MORTALITY IN PATIENTS WITH ULCERATIVE COLITIS UNDERGOING COLECTOMY (2016-2020) Open
Background Despite an expanding armamentarium of medical treatment options, the 10-year cumulative risk of colectomy for patients with ulcerative colitis (UC) remains 5-10%. Surgery for UC is associated with a substantial burden of mortali…
View article: A243 BONE MINERAL DENSITY AND DIETARY BONE NUTRIENTS DIFFER IN PATIENTS WITH CROHN'S DISEASE STRICTURES
A243 BONE MINERAL DENSITY AND DIETARY BONE NUTRIENTS DIFFER IN PATIENTS WITH CROHN'S DISEASE STRICTURES Open
Background Crohn’s disease (CD) phenotypes include inflammatory (non-stricture) and stricture behaviours. Strictures are bowel narrowing’s that may lead to obstructions and subsequent dietary restrictions to prevent blockages. Bone mineral…
View article: A258 ULTRASOUND ASSESSMENT OF CROHN’S DISEASE PATIENTS FOLLOWING RISANKIZUMAB INITIATION; BASELINE, 3 AND 6 MONTH FOLLOW UP
A258 ULTRASOUND ASSESSMENT OF CROHN’S DISEASE PATIENTS FOLLOWING RISANKIZUMAB INITIATION; BASELINE, 3 AND 6 MONTH FOLLOW UP Open
Background Risankizumab (RIS), an interleukin-23 inhibitor specific to the p19 subunit, was approved for the treatment of moderate to severe Crohn’s Disease (CD) in December 2022. Intestinal ultrasound (IUS) is an accurate and well-tolerat…
View article: A168 RATES OF <i>CLOSTRIDIOIDES DIFFICILE</i> INFECTIONS REQUIRING HOSPITALIZATION DURING THE COVID-19 PANDEMIC
A168 RATES OF <i>CLOSTRIDIOIDES DIFFICILE</i> INFECTIONS REQUIRING HOSPITALIZATION DURING THE COVID-19 PANDEMIC Open
Background Clostridium difficile infection (CDI) is the most common cause of nosocomial infectious diarrhea and is associated with a substantial burden of morbidity and mortality. Most cases of CDI are acquired through health care setting …
View article: A234 DOES FECAL CALPROTECTIN CORRELATE WITH INFLAMMATION ON ULTRASOUND IN CROHN’S DISEASE STRICTURES?
A234 DOES FECAL CALPROTECTIN CORRELATE WITH INFLAMMATION ON ULTRASOUND IN CROHN’S DISEASE STRICTURES? Open
Background Fibrostenotic Crohn’s Disease (CD) is a challenging phenotype particularly due to the absence of intestinal anti-fibrotic therapies. Differentiating between strictures that are predominantly fibrotic as opposed to inflammatory r…
View article: P476 Correlation between fecal calprotectin and inflammation on ultrasound in fibrostenotic Crohn’s Disease
P476 Correlation between fecal calprotectin and inflammation on ultrasound in fibrostenotic Crohn’s Disease Open
Background Fibrostenotic Crohn’s Disease (CD) is a challenging phenotype particularly due to the absence of intestinal anti-fibrotic therapies. Differentiating between strictures that are predominantly fibrotic versus inflammatory remains …
View article: P771 Comparing obstructive symptoms and dietary restrictions with Crohn's disease stricture severity
P771 Comparing obstructive symptoms and dietary restrictions with Crohn's disease stricture severity Open
Background Stricturing Crohn’s Disease (CD) is characterized by bowel narrowing often leading to obstruction. Obstructive symptoms (OS) have been evaluated in patients with CD strictures using OS scores (STRIDENT). Clinical observations su…
View article: P107 Comparing the Colonic Tissue Proteome of Active and Inactive Ulcerative Colitis
P107 Comparing the Colonic Tissue Proteome of Active and Inactive Ulcerative Colitis Open
Background Ulcerative colitis (UC) is an inflammatory bowel disease that begins at the rectum and can advance proximally and continuously throughout the colon. In this pilot study, we aim to differentiate the protein expression between act…
View article: P745 Assessment of Crohn’s disease patients following risankizumab initiation using intestinal ultrasound: A prospective study
P745 Assessment of Crohn’s disease patients following risankizumab initiation using intestinal ultrasound: A prospective study Open
Background Risankizumab (RIS) is a humanized monoclonal antibody that inhibits interleukin-23 by binding to its p19 subunit. The use of RIS in the treatment of moderate to severe Crohn’s Disease (CD) was approved in December 2022. Intestin…
View article: Incidence and Prevalence of Primary Sclerosing Cholangitis: A Meta-analysis of Population-based Studies
Incidence and Prevalence of Primary Sclerosing Cholangitis: A Meta-analysis of Population-based Studies Open
Background Primary sclerosing cholangitis is a chronic liver disease associated with significant morbidity, mortality, and healthcare utilization. We conducted a systematic review and meta-analysis of population-based studies of the incide…
View article: Bedside Intestinal Ultrasound Performed in an Inflammatory Bowel Disease Urgent Assessment Clinic Improves Clinical Decision-Making and Resource Utilization
Bedside Intestinal Ultrasound Performed in an Inflammatory Bowel Disease Urgent Assessment Clinic Improves Clinical Decision-Making and Resource Utilization Open
Background Patients with inflammatory bowel disease (IBD) require accessible, timely, and noninvasive strategies to monitor disease. The aim was to assess the integration of intestinal ultrasound (IUS) on decision-making and endoscopy util…
View article: A180 PLACEBO RATES IN MICROSCOPIC COLITIS RANDOMIZED TRIALS: APPLICATIONS FOR FUTURE DRUG DEVELOPMENT USING A HISTORICAL CONTROL ARM
A180 PLACEBO RATES IN MICROSCOPIC COLITIS RANDOMIZED TRIALS: APPLICATIONS FOR FUTURE DRUG DEVELOPMENT USING A HISTORICAL CONTROL ARM Open
Background There remains a need to develop effective medical therapies for patients with microscopic colitis (MC) who do not respond, are intolerant, or relapse on budesonide. Conducting randomized trials in MC is logistically and ethicall…
View article: Editorial: real‐world evidence of tofacitinib and vedolizumab in ulcerative colitis—are we one step closer to better positioning therapies after <scp>anti‐TNF</scp> failure?
Editorial: real‐world evidence of tofacitinib and vedolizumab in ulcerative colitis—are we one step closer to better positioning therapies after <span>anti‐TNF</span> failure? Open
LINKED CONTENT This article is linked to Buisson et al papers. To view these articles, visit https://doi.org/10.1111/apt.17305 and https://doi.org/10.1111/apt.17405
View article: Nutritional interventions in adult fibrostenotic Crohn’s disease: A systematic review
Nutritional interventions in adult fibrostenotic Crohn’s disease: A systematic review Open
Background Management of Crohn’s disease (CD) using dietary interventions has become an area of increased research interest. There is a lack of specific research exploring if diet and nutrition interventions are beneficial in patients with…
View article: P270 A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease
P270 A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease Open
Background Small bowel fibrostenotic strictures are common in patients with Crohn’s disease (CD). No global consensus recommendations on definitions, diagnosis and clinical management are available. Methods Several systematic reviews follo…
View article: P425 The utility of intestinal ultrasound to inform clinical decision making
P425 The utility of intestinal ultrasound to inform clinical decision making Open
Background Inflammatory bowel disease (IBD) is a chronic, immune-mediated disease leading to progressive bowel damage. Objective monitoring is essential to improve outcomes. Intestinal ultrasound (IUS) is an accurate, repeatable modality p…
View article: Successful treatment of concomitant alopecia universalis and Crohn’s disease with upadacitinib: A case report
Successful treatment of concomitant alopecia universalis and Crohn’s disease with upadacitinib: A case report Open
Alopecia areata is a non-scarring, autoimmune hair loss disorder that is associated with inflammatory bowel disease. Alopecia areata and inflammatory bowel disease may have a common pathogenic mechanism that involves the Janus kinase/STAT …
View article: Crohn's disease related strictures in cross‐sectional imaging: More than meets the eye?
Crohn's disease related strictures in cross‐sectional imaging: More than meets the eye? Open
Strictures in Crohn's disease (CD) are a hallmark of long‐standing intestinal damage, brought about by inflammatory and non‐inflammatory pathways. Understanding the complex pathophysiology related to inflammatory infiltrates, extracellular…
View article: 654: A THIRD DOSE OF SARS-COV-2 VACCINE YIELDS HIGH ANTIBODY LEVELS COMPARED TO TWO DOSE VACCINATION SCHEDULE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
654: A THIRD DOSE OF SARS-COV-2 VACCINE YIELDS HIGH ANTIBODY LEVELS COMPARED TO TWO DOSE VACCINATION SCHEDULE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE Open
View article: Su1484: SEROLOGICAL RESPONSES TO SARS-COV-2 VACCINATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY
Su1484: SEROLOGICAL RESPONSES TO SARS-COV-2 VACCINATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A PROSPECTIVE COHORT STUDY Open
View article: A146 THE EFFECTIVENESS OF USTEKINUMAB DOSE ESCALATION IN PATIENTS WITH ULCERATIVE COLITIS
A146 THE EFFECTIVENESS OF USTEKINUMAB DOSE ESCALATION IN PATIENTS WITH ULCERATIVE COLITIS Open
Background Ustekinumab (UST), an IgG1 antibody that targets IL-12/23, is an effective and safe treatment option for patients with inflammatory bowel disease (IBD). Cohort studies have shown that dose escalation is an effective strategy for…