Catlyn Cavender
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View article: Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses
Natural history study of glycan accumulation in large animal models of GM2 gangliosidoses Open
β-hexosaminidase is an enzyme responsible for the degradation of gangliosides, glycans, and other glycoconjugates containing β-linked hexosamines that enter the lysosome. GM2 gangliosidoses, such as Tay-Sachs and Sandhoff, are lysosomal st…