Catriona S. Bradshaw
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View article: Sequencing of <i>Mycoplasma genitalium</i> genomes using a tiling amplicon method on the Nanopore MinION
Sequencing of <i>Mycoplasma genitalium</i> genomes using a tiling amplicon method on the Nanopore MinION Open
Mycoplasma genitalium is challenging to work with and new methods are needed to study this bacterium directly in clinical samples. This study designed and validated a proof-of-concept polymerase chain reaction (PCR)-based ‘tiling’ methodol…
View article: Trends in infections detected in women with pelvic inflammatory disease over a decade (2014–2024): a retrospective case-series
Trends in infections detected in women with pelvic inflammatory disease over a decade (2014–2024): a retrospective case-series Open
View article: <i>In vitro</i> evolution provides insights into mechanisms of <i>Mycoplasma genitalium</i> resistance to moxifloxacin
<i>In vitro</i> evolution provides insights into mechanisms of <i>Mycoplasma genitalium</i> resistance to moxifloxacin Open
Background Current knowledge of Mycoplasma genitalium fluoroquinolone resistance is based on sequence analyses of clinical samples, an approach with limited scope. Many potential resistance mutations have been described but their impact on…
View article: Communicable episode 29: Bacterial vaginosis and male partners
Communicable episode 29: Bacterial vaginosis and male partners Open
View article: Factors that contribute to the success of primary isolation of Mycoplasma genitalium from clinical samples
Factors that contribute to the success of primary isolation of Mycoplasma genitalium from clinical samples Open
Introduction. Mycoplasma genitalium , a small and slow-growing bacterium, has gained notoriety due to rapidly increasing rates of antibiotic resistance. Gap Statement. M. genitalium is difficult to culture, limiting efforts to understand i…
View article: A novel azithromycin resistance mutation in <i>Mycoplasma genitalium</i> induced <i>in vitro</i>
A novel azithromycin resistance mutation in <i>Mycoplasma genitalium</i> induced <i>in vitro</i> Open
Background Mycoplasma genitalium is a sexually transmitted bacterium of increasing concern due to issues around antimicrobial resistance. Resistance is typically mediated by SNPs; however, the difficulty of isolation and culture of M. geni…
View article: Efficacy and tolerability of the combination of minocycline and metronidazole for macrolide-resistant <i>Mycoplasma genitalium</i>
Efficacy and tolerability of the combination of minocycline and metronidazole for macrolide-resistant <i>Mycoplasma genitalium</i> Open
Background and objectives Curing Mycoplasma genitalium is challenging in the context of rising antimicrobial resistance and limited therapeutic options. There is an urgent need for globally relevant and effective treatment options using re…
View article: Evaluation of artificial intelligence (AI) chatbots for providing sexual health information: a consensus study using real-world clinical queries
Evaluation of artificial intelligence (AI) chatbots for providing sexual health information: a consensus study using real-world clinical queries Open
View article: Communicable Episode 19: ‘Super gonorrhoea’ & other sexually transmitted infections
Communicable Episode 19: ‘Super gonorrhoea’ & other sexually transmitted infections Open
View article: GBTQ+ safe sex entanglements: Finding the bacterial in the age of resistant STIs and prevention innovation
GBTQ+ safe sex entanglements: Finding the bacterial in the age of resistant STIs and prevention innovation Open
Few studies have explored community experiences of our increasingly resistant bacterial landscape, and, in the sphere of sexually transmissible infections (STIs) and antimicrobial resistance, there is even greater absence of community-cent…
View article: Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: an updated systematic review and meta-analysis
Evolving patterns of macrolide and fluoroquinolone resistance in Mycoplasma genitalium: an updated systematic review and meta-analysis Open
Australian Research Council.
View article: Getting Everyone on Board to Break the Cycle of Bacterial Vaginosis (BV) Recurrence: A Qualitative Study of Partner Treatment for BV
Getting Everyone on Board to Break the Cycle of Bacterial Vaginosis (BV) Recurrence: A Qualitative Study of Partner Treatment for BV Open
View article: Diversity of Mycoplasma genitalium strains in Australia: relationship with sexual networks and antimicrobial resistance
Diversity of Mycoplasma genitalium strains in Australia: relationship with sexual networks and antimicrobial resistance Open
Purpose Molecular typing can identify relationships between M. genitalium strains and antimicrobial resistance and demographic data. We examined the association of mgpB sequence types (STs) with sex/sexual orientation, antimicrobial resist…
View article: Routine Treatment Versus Selective Treatment for Individuals Reporting Contact With Sexual Partners With Chlamydia: A Before-and-After Study
Routine Treatment Versus Selective Treatment for Individuals Reporting Contact With Sexual Partners With Chlamydia: A Before-and-After Study Open
Background Many international guidelines recommend routine treatment for individuals reporting sexual contact with sexual partners with chlamydia. In October 2019, the Melbourne Sexual Health Centre (MSHC) changed routine treatment of all …
View article: Trends in infections detected in women with cervicitis over a decade
Trends in infections detected in women with cervicitis over a decade Open
Objectives There is a growing body of evidence that in the absence of Chlamydia trachomatis and/or Neisseria gonorrhoeae, Mycoplasma genitalium and bacterial vaginosis (BV) are associated with cervicitis. We aimed to describe infections de…
View article: CRISPR-Cas-b-Based Diagnostics for Point-of-Care Detection of Sexually Transmitted Infections: A Laboratory Development and Evaluation Study
CRISPR-Cas-b-Based Diagnostics for Point-of-Care Detection of Sexually Transmitted Infections: A Laboratory Development and Evaluation Study Open
View article: Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis: A Cost-Effectiveness Study
Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis: A Cost-Effectiveness Study Open
View article: Duration of kissing in different intimate positions among men who have sex with men: A cross-sectional study
Duration of kissing in different intimate positions among men who have sex with men: A cross-sectional study Open
Background Despite mounting evidence showing that kissing (tongue-kissing) may transmit gonorrhoea between men who have sex with men (MSM), little data exists on factors influencing the duration of kissing while they are above and/or lying…
View article: The genital tract microbiota of IVF patients and oocyte donors: a comparative analysis
The genital tract microbiota of IVF patients and oocyte donors: a comparative analysis Open
Recent studies have observed an association between genital tract microbiota and reproductive outcomes in patients undergoing in vitro fertilization (IVF). This finding could be caused by ascending dysbiosis from the vagina to the endometr…
View article: Real-World Evaluation of Artificial Intelligence (AI) Chatbots for Providing Sexual Health Information: A Consensus Study Using Clinical Queries
Real-World Evaluation of Artificial Intelligence (AI) Chatbots for Providing Sexual Health Information: A Consensus Study Using Clinical Queries Open
Introduction Artificial Intelligence (AI) chatbots could potentially provide information on sensitive topics, including sexual health, to the public. However, their performance compared to human clinicians and across different AI chatbots,…
View article: Polymicrobial consortia in the pathogenesis of biofilm vaginosis visualized by FISH. Historic review outlining the basic principles of the polymicrobial infection theory
Polymicrobial consortia in the pathogenesis of biofilm vaginosis visualized by FISH. Historic review outlining the basic principles of the polymicrobial infection theory Open
The manuscript disputes the exclusive mono-infectious way of thinking, which presumes that for every infection only one pathogen is responsible and sufficient, when infectious vectors, close contact and reduced immunity meet. In situations…
View article: Individualised treatment of sexually transmitted infections by rapid molecular assays
Individualised treatment of sexually transmitted infections by rapid molecular assays Open
Antimicrobial resistance (AMR) is a major problem in the field of sexually transmitted infections (STIs), where escalating levels have coincided with a surge in infections. The individualised treatment of STIs by rapid molecular ‘resistanc…
View article: Validation of self-reported human papillomavirus vaccination in young adult men who have sex with men
Validation of self-reported human papillomavirus vaccination in young adult men who have sex with men Open
The Victorian Government introduced a time-limited human papillomavirus (HPV) catch-up program for gay, bisexual, and other men who have sex with men (GBMSM) aged ≤ 26 years in 2017-2019. We conducted a retrospective observational study to…
View article: Vaginal anaerobes are associated with cervicitis: A case-control study
Vaginal anaerobes are associated with cervicitis: A case-control study Open
We report a positive association between non-optimal vaginal microbiota composition and STI-negative cervicitis. Specific anaerobic BV-associated bacteria may represent infectious causes of cervicitis.
View article: Prevalence of Cefixime-Resistant <i>Neisseria gonorrhoeae</i> in Melbourne, Australia, 2021–2022
Prevalence of Cefixime-Resistant <i>Neisseria gonorrhoeae</i> in Melbourne, Australia, 2021–2022 Open
While ceftriaxone remains the first-line treatment for gonorrhea, the US Centers for Disease Control and Prevention recommended cefixime as a second-line treatment in 2021. We tested 1176 Neisseria gonorrhoeae isolates among clients attend…
View article: Mycoplasma genitalium in pregnancy, including specific co-infections, is associated with lower birthweight: A prospective cohort study
Mycoplasma genitalium in pregnancy, including specific co-infections, is associated with lower birthweight: A prospective cohort study Open
View article: Systematic Review and Meta-analysis of the Association Between<i>Mycoplasma Genitalium</i>and Pelvic Inflammatory Disease (PID)
Systematic Review and Meta-analysis of the Association Between<i>Mycoplasma Genitalium</i>and Pelvic Inflammatory Disease (PID) Open
Background Differences in opinion concerning the contribution of Mycoplasma genitalium to pelvic inflammatory disease (PID) has resulted in inconsistencies across global testing and treatment guidelines. We conducted a systematic review an…
View article: Cost-effectiveness of resistance-guided therapy for Mycoplasma genitalium in Australia
Cost-effectiveness of resistance-guided therapy for Mycoplasma genitalium in Australia Open
The recommended first-line treatment for Mycoplasma genitalium infections is azithromycin. However, the prevalence of macrolide resistance for M. genitalium has increased to more than 50% worldwide. In 2013, Australia introduced a resistan…
View article: Volume 45 Number 2
Volume 45 Number 2 Open
What a fantastic line-
View article: The AMR Hub: a public–private partnership to overcome barriers to commercialisation and deliver antimicrobial stewardship innovations
The AMR Hub: a public–private partnership to overcome barriers to commercialisation and deliver antimicrobial stewardship innovations Open
Antimicrobial resistance (AMR) is recognised as one of the greatest scientific challenges of the 21st century, disproportionately affecting people living in low- and middle-income countries. With bacterial pathogens becoming increasingly r…