C.C. Morton
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View article: Exaggerated NMDA Receptor–Primed Metaplasticity via SK Channel Dysregulation in <i>Fmr1</i> Knockout Mice
Exaggerated NMDA Receptor–Primed Metaplasticity via SK Channel Dysregulation in <i>Fmr1</i> Knockout Mice Open
Fragile X syndrome (FXS), the most common monogenic neurodevelopmental disorder associated with autism and intellectual disability, results from the loss of expression of the FMR1 gene. Synaptic and circuit-level abnormalities are well doc…
View article: A vector-based strategy for olfactory navigation in <i>Drosophila</i>
A vector-based strategy for olfactory navigation in <i>Drosophila</i> Open
Odors serve as essential cues for navigation. Although tracking an odor plume has been modeled as a reflexive process, it remains unclear whether animals can use memories of their past odor encounters to infer the spatial structure of thei…
View article: Nucleotide-level resolution of a complex chromosomal rearrangement associated with cognitive disabilities reveals chromothripsis
Nucleotide-level resolution of a complex chromosomal rearrangement associated with cognitive disabilities reveals chromothripsis Open
Chromothripsis is an extreme form of complex chromosomal rearrangement (CCR), characterized by a localized shattering and random reassembly of genomic fragments. The aim of this study is the characterization at sequence-level resolution of…
View article: Genomic landscape of balanced cytogenetic abnormalities in subjects with multiple congenital anomalies
Genomic landscape of balanced cytogenetic abnormalities in subjects with multiple congenital anomalies Open
Balanced chromosomal abnormalities (BCAs) represent a unique class of genomic variation that involves large rearrangement of the chromosomes. To date their detection has been limited to cytogenetic resolution as most first-tier genetic scr…
View article: P12.18 Sexual and reproductive health in rural victoria: what urgent care services are available and are they adequate?
P12.18 Sexual and reproductive health in rural victoria: what urgent care services are available and are they adequate? Open
Introduction Strong evidence exists that young, rural people face significant barriers to accessing sexual and reproductive health (SRH) services. What influence this has on chlamydia notifications is unknown. Regional hospital urgent care…