Cecilie G. Nome
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View article: Clinical outcome after thrombectomy in patients with MeVO stroke: importance of clinical and technical factors
Clinical outcome after thrombectomy in patients with MeVO stroke: importance of clinical and technical factors Open
Background and aims Whereas high-level evidence has been proven for safety and efficacy of endovascular treatment (EVT) in large vessel occlusion (LVO) stroke, the evidence for EVT in medium vessel occlusion (MeVO) in both sexes and differ…
View article: Predictors of outcome after endovascular treatment for tandem occlusions: a single center retrospective analysis
Predictors of outcome after endovascular treatment for tandem occlusions: a single center retrospective analysis Open
Background The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. The aim of this study was to identify clinical and procedural factors that may…
View article: Predictors of outcome after endovascular treatment for Tandem Occlusions: a single center retrospective analysis
Predictors of outcome after endovascular treatment for Tandem Occlusions: a single center retrospective analysis Open
Background The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. The aim of this study was to identify clinical and procedural factors that may…
View article: Differential Glial Activation in Early Epileptogenesis—Insights From Cell-Specific Analysis of DNA Methylation and Gene Expression in the Contralateral Hippocampus
Differential Glial Activation in Early Epileptogenesis—Insights From Cell-Specific Analysis of DNA Methylation and Gene Expression in the Contralateral Hippocampus Open
Background and Aims: Morphological changes in mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) are well-characterized. Yet, it remains elusive whether these are a consequence of seizures or originate from a hithert…
View article: Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy Open
View article: Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis
Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis Open
We found neuron- and glia-specific changes in DNAm and gene expression in early epileptogenesis. We detected single genetic loci in several epilepsy-related genes, where DNAm and GE changes coincide, worth further investigation. Further, o…
View article: Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity
Ca2+ Signals in Astrocytes Facilitate Spread of Epileptiform Activity Open
Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte-neuron interplay remains elusive. By using 2-photon imaging of awake head-fixed mice with chronic hippo…
View article: Evaluation of long-term antiepileptic drug use in patients with temporal lobe epilepsy: Assessment of risk factors for drug resistance and polypharmacy
Evaluation of long-term antiepileptic drug use in patients with temporal lobe epilepsy: Assessment of risk factors for drug resistance and polypharmacy Open