Cedric Dicko
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View article: Injectable bioresorbable conductive hydrogels for multimodal brain tumor electroimmunotherapy
Injectable bioresorbable conductive hydrogels for multimodal brain tumor electroimmunotherapy Open
Current electrode technologies are too rigid for safe and effective delivery of electrotherapy in the brain, and patients with glioblastoma continue to face a devastating prognosis, with median survival stalled at 15 months despite intensi…
View article: pH-Triggered Clustering Regulates β-sheet Activation in Silk Assembly
pH-Triggered Clustering Regulates β-sheet Activation in Silk Assembly Open
Silk fibres derive their exceptional properties from hierarchical protein organisation, yet the molecular pathways guiding this evolution remain poorly resolved. During regenerated silk fibroin gelation under biomimetic gradual acidificati…
View article: Preparation and Utilization of a Highly Discriminative Absorbent Imprinted with Fetal Hemoglobin
Preparation and Utilization of a Highly Discriminative Absorbent Imprinted with Fetal Hemoglobin Open
Development in hemoglobin-based oxygen carriers (HBOCs) that may be used as alternatives to donated blood requires an extensive supply of highly pure hemoglobin (Hb) preparations. Therefore, it is essential to fabricate inexpensive, stable…
View article: In situ assembly of an injectable cardiac stimulator
In situ assembly of an injectable cardiac stimulator Open
Without intervention, cardiac arrhythmias pose a risk of fatality. However, timely intervention can be challenging in environments where transporting a large, heavy defibrillator is impractical, or emergency surgery to implant cardiac stim…
View article: Stabilization of Non-Native Folds and Programmable Protein Gelation in Compositionally Designed Deep Eutectic Solvents
Stabilization of Non-Native Folds and Programmable Protein Gelation in Compositionally Designed Deep Eutectic Solvents Open
Proteins are adjustable units from which biomaterials with designed properties can be developed. However, non-native folded states with controlled topologies are hardly accessible in aqueous environments, limiting their prospects as buildi…
View article: Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins
Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins Open
The preservation of labile biomolecules presents a major challenge in chemistry, and deep eutectic solvents (DESs) have emerged as suitable environments for this purpose. However, how the hydration of DESs impacts the behavior of proteins …
View article: Interaction of haemin with albumin-based macroporous cryogel: Adsorption isotherm and fluorescence quenching studies
Interaction of haemin with albumin-based macroporous cryogel: Adsorption isotherm and fluorescence quenching studies Open
Albumin-based cryogels for capturing haemin were synthesised by crosslinking different biomolecules, bovine serum albumin (BSA) and ovalbumin (OVA). The impact of the protein and coupling agent concentrations on cryogel’s mechanical proper…
View article: The Influence of pH on the Lipase Digestion of Nanosized Triolein, Diolein and Monoolein Films
The Influence of pH on the Lipase Digestion of Nanosized Triolein, Diolein and Monoolein Films Open
Herein we studied the processes at the liquid aqueous interface at pH 7 and 8.5 during Thermomyces lanuginosus lipase-catalyzed hydrolysis of nanosized tri-, di- and mono-olein films deposited on a planar substrate. By employing a combinat…
View article: Data for Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins
Data for Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins Open
This dataset contains the full set of data related to the publication "Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins", published in the Journal of the American Chemical Soci…
View article: Data for Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins
Data for Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins Open
This dataset contains the full set of data related to the publication "Hydration in Deep Eutectic Solvents Induces Non-monotonic Changes in the Conformation and Stability of Proteins", published in the Journal of the American Chemical Soci…
View article: Supercritical Carbon Dioxide Impregnation of Gold Nanoparticles Demonstrates a New Route for the Fabrication of Hybrid Silk Materials
Supercritical Carbon Dioxide Impregnation of Gold Nanoparticles Demonstrates a New Route for the Fabrication of Hybrid Silk Materials Open
How many nanoparticles can we load in a fiber? How much will leak? Underlying is the relatively new question of the “space available” in fibers for nanoparticle loading. Here, using supercritical carbon dioxide (scCO2) as a carrier fluid, …
View article: Site-Specific Introduction of Negative Charges on the Protein Surface for Improving Global Functions of Recombinant Fetal Hemoglobin
Site-Specific Introduction of Negative Charges on the Protein Surface for Improving Global Functions of Recombinant Fetal Hemoglobin Open
Due to its compatible oxygen-transporting abilities, hemoglobin (Hb) is a protein of interest in the development of artificial oxygen therapeutics. Despite continuous formulation attempts, extracellular Hb solution often exhibits undesirab…
View article: Geographical variation in total phenolics, flavonoids and antioxidant activities of Eucalyptus camaldulensis leaves in Burkina Faso
Geographical variation in total phenolics, flavonoids and antioxidant activities of Eucalyptus camaldulensis leaves in Burkina Faso Open
This study aimed to elucidate the effect of sampling location of Eucalyptus camaldulensis leaves on antioxidant activity, total phenolic content (TPC) and total flavonoid content (TFC). Leaves of E. camaldulensis collected at three differe…
View article: 3D Structure and Mechanics of Silk Sponge Scaffolds Is Governed by Larger Pore Sizes
3D Structure and Mechanics of Silk Sponge Scaffolds Is Governed by Larger Pore Sizes Open
Three-dimensional scaffolds play an essential role in tissue engineering. Although essential, the tunability of the 3D scaffolds mechanical and transport properties remains a challenge. In this work, we present new approaches to advance th…
View article: Structural Diversity of Native Major Ampullate, Minor Ampullate, Cylindriform, and Flagelliform Silk Proteins in Solution
Structural Diversity of Native Major Ampullate, Minor Ampullate, Cylindriform, and Flagelliform Silk Proteins in Solution Open
The foundations of silk spinning, the structure, storage, and activation of silk proteins, remain highly debated. By combining solution small-angle neutron and X-ray scattering (SANS and SAXS) alongside circular dichroism (CD), we reveal a…
View article: Ag–Polymer Nanocomposites for Capture, Detection, and Destruction of Bacteria
Ag–Polymer Nanocomposites for Capture, Detection, and Destruction of Bacteria Open
Bacterial infection is one of the major problems for human health. To prevent outbreak of bacteria-caused diseases, early diagnosis of bacterial pathogen and effective destruction of pathogenic microorganisms are in urgent need. In this wo…
View article: Complex three-dimensional self-assembly in proxies for atmospheric aerosols
Complex three-dimensional self-assembly in proxies for atmospheric aerosols Open
View article: Fabrication and Optimization of Stable, Optically Transparent, and Reusable pH-Responsive Silk Membranes
Fabrication and Optimization of Stable, Optically Transparent, and Reusable pH-Responsive Silk Membranes Open
The fabrication of silk-based membranes that are stable, optically transparent and reusable is yet to be achieved. To address this bottleneck we have developed a method to produce transparent chromogenic silk patches that are optically res…
View article: Structural Response of Human Serum Albumin to Oxidation: Biological Buffer to Local Formation of Hypochlorite
Structural Response of Human Serum Albumin to Oxidation: Biological Buffer to Local Formation of Hypochlorite Open
The most abundant plasma protein, human serum albumin (HSA), plays a key part in the body's antioxidant defense against reactive species. This study was aimed at correlating oxidant-induced chemical and structural effects on HSA. Despite t…
View article: Novel Approach to Controlled Surface Modification in Textile Via Magnetic Cross- Linked Enzyme Aggregates (Clea)
Novel Approach to Controlled Surface Modification in Textile Via Magnetic Cross- Linked Enzyme Aggregates (Clea) Open
In this proceeding, architecting novel magnetic Cross-Linked-Enzyme-Aggregates (CLEA) nanoparticles to effectively and controllably modify textile surfaces without damaging the fabric itself, will be discussed. The efficiency is due to exp…