Celeste Dufour
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View article: A “Prime and Expand” strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy
A “Prime and Expand” strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy Open
Adoptive cellular therapy (ACT) using memory-like (ML) natural killer (NK) cells, generated through overnight ex vivo activation with IL-12, IL-15, and IL-18, has shown promise for treating hematologic malignancies. We recently reported th…
View article: 195 Characterization of WU-NK-101, a feeder cell-free expanded allogeneic memory NK cell product with potent anti-tumor activity
195 Characterization of WU-NK-101, a feeder cell-free expanded allogeneic memory NK cell product with potent anti-tumor activity Open
Background Cytokine-induced memory NK cells, like WU-NK-101, offer several advantages over conventional NK cells.1, 2 These advantages include enhanced functional persistence, efficacy, and metabolic fitness that improve their survival and…