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View article: Maintenance of Primary Human Colorectal Cancer Microenvironment Using a Perfusion Bioreactor‐Based 3D Culture System
Maintenance of Primary Human Colorectal Cancer Microenvironment Using a Perfusion Bioreactor‐Based 3D Culture System Open
Colorectal cancer (CRC) is a leading cause of cancer‐related death. Conventional chemotherapeutic regimens have limited success rates, and a major challenge for the development of novel therapies is the lack of adequate in vitro models. No…
View article: In Vitro Modeling of Tumor–Immune System Interaction
In Vitro Modeling of Tumor–Immune System Interaction Open
Immunotherapy has emerged during the past two decades as an innovative and successful form of cancer treatment. However, frequently, mechanisms of actions are still unclear, predictive markers are insufficiently characterized, and preclini…
View article: Establishment Of The Culture Condition To Maintain The Primary Human Colorectal Cancer Microenvironment By Using A 3D Perfusion Bioreactor
Establishment Of The Culture Condition To Maintain The Primary Human Colorectal Cancer Microenvironment By Using A 3D Perfusion Bioreactor Open
The screening and assessment of new cancer drugs has for many years carried out on conventional 2D monolayer cell culture that cannot represent the complexity of a tissue. On the other hand, the generation of patient derived xenograft (PDX…