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View article: Impact of adapted physical activity and diet counselling on health-related quality of life in women undergoing adjuvant breast cancer therapy
Impact of adapted physical activity and diet counselling on health-related quality of life in women undergoing adjuvant breast cancer therapy Open
In the monocentric APAD1 trial, 143 women with non-metastatic breast cancer were randomised to undergo either an adapted physical activity and diet counselling (APAD) program or usual care. Health-related quality of life (HRQoL) was prospe…
View article: HE4 and CA-125 kinetics to predict outcome in patients with recurrent epithelial ovarian carcinoma: the META4 clinical trial
HE4 and CA-125 kinetics to predict outcome in patients with recurrent epithelial ovarian carcinoma: the META4 clinical trial Open
HE4 and CA-125 are used for epithelial ovarian cancer (EOC) screening, diagnosis, and follow-up. Our objective was to study HE4 and CA-125 kinetics in patients treated for recurrent EOC. Serum samples were prospectively collected before th…
View article: Benefits of cardiac coherence combined with medical hypnosis on preoperative anxiety before cancer surgery: the COHEC II study trial protocol
Benefits of cardiac coherence combined with medical hypnosis on preoperative anxiety before cancer surgery: the COHEC II study trial protocol Open
Introduction Preoperative anxiety is a frequent problem that can lead to complications both during anaesthesia and in the postoperative period, especially in oncology. Studies have shown that it can be managed using non-pharmacological app…
View article: Time-Dependent ROC Curve Analysis for Assessing the Capability of Radiation-Induced CD8 T-Lymphocyte Apoptosis to Predict Late Toxicities after Adjuvant Radiotherapy of Breast Cancer Patients
Time-Dependent ROC Curve Analysis for Assessing the Capability of Radiation-Induced CD8 T-Lymphocyte Apoptosis to Predict Late Toxicities after Adjuvant Radiotherapy of Breast Cancer Patients Open
Late fibrosis can occur in breast cancer patients treated with curative-intent radiotherapy. Predicting this toxicity is of clinical interest in order to adapt the irradiation dose delivered. Radiation-induced CD8 T-lymphocyte apoptosis (R…
View article: Quality of life and response shift effect of diffuse large B‐cell lymphoma French patients included in prospective real‐life REALYSA cohort in the first year after diagnosis
Quality of life and response shift effect of diffuse large B‐cell lymphoma French patients included in prospective real‐life REALYSA cohort in the first year after diagnosis Open
Introduction: Few quality of life (QoL) data are available for diffuse large B-cell lymphoma (DLBCL) patients during the first year of diagnosis. Due to the disease and treatment, patients can adapt to their condition and then change their…
View article: When a joint model should be preferred over a linear mixed model for analysis of longitudinal health-related quality of life data in cancer clinical trials
When a joint model should be preferred over a linear mixed model for analysis of longitudinal health-related quality of life data in cancer clinical trials Open
View article: A Phase II Multicenter Trial on High-Dose Vitamin D Supplementation for the Correction of Vitamin D Insufficiency in Patients with Breast Cancer Receiving Adjuvant Chemotherapy
A Phase II Multicenter Trial on High-Dose Vitamin D Supplementation for the Correction of Vitamin D Insufficiency in Patients with Breast Cancer Receiving Adjuvant Chemotherapy Open
Breast cancer (BC) treatments induce vitamin D (VD) insufficiency and bone metabolism changes, resulting in osteoporosis and skeletal morbidity risk. We report the results of a bicentric phase II trial (ClinicalTrials.gov Identifier: NCT04…
View article: Joint modelling with competing risks of dropout for longitudinal analysis of health-related quality of life in cancer clinical trials
Joint modelling with competing risks of dropout for longitudinal analysis of health-related quality of life in cancer clinical trials Open
View article: Changes in vitamin D and calcium metabolism markers in patients undergoing adjuvant chemotherapy for breast cancer
Changes in vitamin D and calcium metabolism markers in patients undergoing adjuvant chemotherapy for breast cancer Open
View article: Handling informative dropout in longitudinal analysis of health-related quality of life: application of three approaches to data from the esophageal cancer clinical trial PRODIGE 5/ACCORD 17
Handling informative dropout in longitudinal analysis of health-related quality of life: application of three approaches to data from the esophageal cancer clinical trial PRODIGE 5/ACCORD 17 Open
View article: GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials
GUIP1: a R package for dose escalation strategies in phase I cancer clinical trials Open
View article: A New Score to Predict the Resectability of Pancreatic Adenocarcinoma: The BACAP Score
A New Score to Predict the Resectability of Pancreatic Adenocarcinoma: The BACAP Score Open
Surgery remains the only curative treatment for pancreatic ductal adenocarcinoma (PDAC). Therefore, a predictive score for resectability on diagnosis is needed. A total of 814 patients were included between 2014 and 2017 from 15 centers in…
View article: Correcting for misclassification and selection effects in estimating net survival in clinical trials
Correcting for misclassification and selection effects in estimating net survival in clinical trials Open
View article: Distribution- and anchor-based methods to determine the minimally important difference on patient-reported outcome questionnaires in oncology: a structured review
Distribution- and anchor-based methods to determine the minimally important difference on patient-reported outcome questionnaires in oncology: a structured review Open
View article: <b>SmoothHazard</b>: An <i>R</i> Package for Fitting Regression Models to Interval-Censored Observations of Illness-Death Models
<b>SmoothHazard</b>: An <i>R</i> Package for Fitting Regression Models to Interval-Censored Observations of Illness-Death Models Open
The irreversible illness-death model describes the pathway from an initial state to an absorbing state either directly or through an intermediate state. This model is frequently used in medical applications where the intermediate state rep…
View article: Gait Speed and Decline in Gait Speed as Predictors of Incident Dementia
Gait Speed and Decline in Gait Speed as Predictors of Incident Dementia Open
Gait is slower up to 7 years prior to clinical onset of dementia. Decline in GS is also more accelerated, suggesting strong links between cognitive and motor function in older adults.