Céline Baldeyron
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View article: The DNA damage response in myogenic C2C7 cells depends on the characteristics of ionizing particles
The DNA damage response in myogenic C2C7 cells depends on the characteristics of ionizing particles Open
DNA integrity and stability are vital for proper cellular activity. Nevertheless, to treat cancer patients, DNA is the main target for inducing tumoral cell death. Nowadays, cancer treatment is improving by the development of new technolog…
View article: The DNA damage response in myogenic C2C7 cells depends on the characteristics of ionizing particles
The DNA damage response in myogenic C2C7 cells depends on the characteristics of ionizing particles Open
DNA integrity and stability are vital for proper cellular activity. Nevertheless, to treat cancer patients, DNA is the main target for inducing tumoral cell death. Nowadays, cancer treatment is improving by the development of new technolog…
View article: Decline of DNA damage response along with myogenic differentiation
Decline of DNA damage response along with myogenic differentiation Open
DNA integrity is incessantly confronted to agents inducing DNA lesions. All organisms are equipped with a network of DNA damage response mechanisms that will repair DNA lesions and restore proper cellular activities. Despite DNA repair mec…
View article: Decline of DNA damage response along with myogenic differentiation
Decline of DNA damage response along with myogenic differentiation Open
DNA integrity is incessantly confronted to endogenous and exogenous agents inducing DNA lesions, which are harmful for cellular homeostasis. Luckily all organisms are equipped with a network of DNA damage response (DDR) mechanisms that wil…
View article: Differential Recruitment of DNA Repair Proteins KU70/80 and RAD51 upon Microbeam Irradiation with α-Particles
Differential Recruitment of DNA Repair Proteins KU70/80 and RAD51 upon Microbeam Irradiation with α-Particles Open
In addition to representing a significant part of the natural background radiation exposure, α-particles are thought to be a powerful tool for targeted radiotherapy treatments. Understanding the molecular mechanisms of recognition, signali…
View article: Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage
Real-Time Tracking of Parental Histones Reveals Their Contribution to Chromatin Integrity Following DNA Damage Open
View article: Molding BRCA2 function through its interacting partners
Molding BRCA2 function through its interacting partners Open
The role of the tumor suppressor BRCA2 has been shaped over 2 decades thanks to the discovery of its protein and nucleic acid partners, biochemical and structural studies of the protein, and the functional evaluation of germline variants i…
View article: TIPIN depletion leads to apoptosis in breast cancer cells
TIPIN depletion leads to apoptosis in breast cancer cells Open
Triple‐negative breast cancer (TNBC) is the breast cancer subgroup with the most aggressive clinical behavior. Alternatives to conventional chemotherapy are required to improve the survival of TNBC patients. Gene‐expression analyses for di…