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View article: LAP2alpha facilitates myogenic gene expression by preventing nucleoplasmic lamin A/C from spreading to active chromatin regions
LAP2alpha facilitates myogenic gene expression by preventing nucleoplasmic lamin A/C from spreading to active chromatin regions Open
A-type lamins form a filamentous meshwork beneath the nuclear membrane that anchors large heterochromatic genomic regions at the nuclear periphery. A-type lamins also exist as a dynamic, non-filamentous pool in the nuclear interior, where …
View article: Genetic analysis of a phenotypic loss in the mechanosensory entrainment of a circalunar clock
Genetic analysis of a phenotypic loss in the mechanosensory entrainment of a circalunar clock Open
Genetic variants underlying traits that become either non-adaptive or selectively neutral are expected to have altered evolutionary trajectories. Uncovering genetic signatures associated with phenotypic loss presents the opportunity to dis…
View article: Polygenic adaptation from standing genetic variation allows rapid ecotype formation
Polygenic adaptation from standing genetic variation allows rapid ecotype formation Open
Adaptive ecotype formation can be the first step to speciation, but the genetic underpinnings of this process are poorly understood. Marine midges of the genus Clunio (Diptera) have recolonized Northern European shore areas after the last …
View article: Author response: Polygenic adaptation from standing genetic variation allows rapid ecotype formation
Author response: Polygenic adaptation from standing genetic variation allows rapid ecotype formation Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Methods Data availability References Decision letter Author response Article and author information Metrics Abstract Adaptive ecotype formation can be th…
View article: Genetic analysis of a phenotypic loss in the mechanosensory entrainment of a circalunar clock
Genetic analysis of a phenotypic loss in the mechanosensory entrainment of a circalunar clock Open
Genetic variants underlying traits that become either non-adaptive or selectively neutral are expected to have altered evolutionary trajectories. Uncovering genetic signatures associated with phenotypic loss presents the opportunity to dis…
View article: Polygenic adaptation from standing genetic variation allows rapid ecotype formation
Polygenic adaptation from standing genetic variation allows rapid ecotype formation Open
Adaptive ecotype formation is the first step to speciation, but the genetic underpinnings of this process are poorly understood. Marine midges of the genus Clunio (Diptera) have recolonized Northern European shore areas after the last glac…
View article: A compendium of genome-wide sequence reads from NBS (nucleotide binding site) domains of resistance genes in the common potato
A compendium of genome-wide sequence reads from NBS (nucleotide binding site) domains of resistance genes in the common potato Open
SolariX is a compendium of DNA sequence tags from the nucleotide binding site (NBS) domain of disease resistance genes of the common potato, Solanum tuberosum Group Tuberosum. The sequences, which we call NBS tags, for nearly all NBS domai…
View article: An Enumerative Combinatorics Model for Fragmentation Patterns in RNA Sequencing Provides Insights into Nonuniformity of the Expected Fragment Starting-Point and Coverage Profile
An Enumerative Combinatorics Model for Fragmentation Patterns in RNA Sequencing Provides Insights into Nonuniformity of the Expected Fragment Starting-Point and Coverage Profile Open
RNA sequencing (RNA-seq) has emerged as the method of choice for measuring the expression of RNAs in a given cell population. In most RNA-seq technologies, sequencing the full length of RNA molecules requires fragmentation into smaller pie…