Edward Araujo Júnior
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View article: Oropouche virus infection in pregnancy: emerging evidence on vertical transmission and perinatal outcomes
Oropouche virus infection in pregnancy: emerging evidence on vertical transmission and perinatal outcomes Open
Oropouche virus infection should be recognized as an emerging threat to maternal and fetal health. Accumulating evidence of vertical transmission and congenital involvement underscores the need to include Oropouche virus in the differentia…
View article: Maternal–Fetal Implications of Chikungunya Virus Infection: An Updated Review
Maternal–Fetal Implications of Chikungunya Virus Infection: An Updated Review Open
Chikungunya virus (CHIKV) infection during pregnancy represents an increasing public health concern, especially in endemic and epidemic regions. The main concern is vertical transmission, particularly during the peripartum period, which ca…
View article: Global Perspectives on HPV Vaccination: Achievements, Challenges, and Lessons from the Brazilian Experience
Global Perspectives on HPV Vaccination: Achievements, Challenges, and Lessons from the Brazilian Experience Open
Background: The introduction of prophylactic HPV vaccination has transformed cervical cancer prevention worldwide, yet many low- and middle-income countries face persistent challenges in implementation, coverage gaps, and vaccine hesitancy…
View article: Maternal and infant outcomes of planned mode of delivery in twin pregnancies: A systematic review and meta‐analysis
Maternal and infant outcomes of planned mode of delivery in twin pregnancies: A systematic review and meta‐analysis Open
Introduction The optimal mode of delivery for twins has been debated for decades. The objective of this study is to compare maternal and perinatal outcomes between planned cesarean birth and planned vaginal delivery in twin pregnancies. Ma…
View article: Fetal Surgery for Congenital Heart Diseases: A Systematic Review and Single-Arm Meta-analysis
Fetal Surgery for Congenital Heart Diseases: A Systematic Review and Single-Arm Meta-analysis Open
FCI for CHD are associated with moderate overall survival but substantial perinatal mortality. Standardized protocols, refined patient selection, and multicenter collaboration are needed to improve outcomes and guide clinical decision-maki…
View article: Factors Associated with Pain Levels During Office Hysteroscopy: A Cross-Sectional Study
Factors Associated with Pain Levels During Office Hysteroscopy: A Cross-Sectional Study Open
The goal of this study was to identify factors associated with pain sensitivity, procedural discomfort, and referral for surgical hysteroscopy, aiming to improve office hysteroscopy success rates. This was an observational prospective cros…
View article: Diagnosis and Surgical Treatment of Hydatidiform Mole
Diagnosis and Surgical Treatment of Hydatidiform Mole Open
Hydatidiform mole is a trophoblastic disorder resulting from abnormal fertilization. Diagnosis is established through a combination of clinical findings, elevated serum human chorionic gonadotropin (hCG) levels, and characteristic features…
View article: Prenatal Ultrasonographic Markers of Macrossomia and C-Peptide in Gestational Diabetes Mellitus: A Prospective Cohort Study
Prenatal Ultrasonographic Markers of Macrossomia and C-Peptide in Gestational Diabetes Mellitus: A Prospective Cohort Study Open
Objective: To investigate the association between prenatal ultrasonographic markers of macrossomia and C-peptide, a neonatal hyperinsulinemia marker, in pregnancies complicated by gestational diabetes mellitus (GDM), with a focus on fetal …
View article: Molar Pregnancy: Early Diagnosis, Clinical Management, and the Role of Referral Centers
Molar Pregnancy: Early Diagnosis, Clinical Management, and the Role of Referral Centers Open
Molar pregnancy (MP) is a gestational disorder resulting from abnormal fertilization, leading to atypical trophoblastic proliferation and the formation of a complete or partial hydatidiform mole. This condition represents the most common f…
View article: HTLV-1 in Pregnancy and Neonatal Health: Evidence, Challenges, and Future Directions
HTLV-1 in Pregnancy and Neonatal Health: Evidence, Challenges, and Future Directions Open
Human T-cell lymphotropic virus (HTLV), a retrovirus associated with severe conditions such as leukemia/lymphoma and myelopathy, exhibits variable global prevalence, with higher rates observed in regions such as northeastern Brazil and sub…
View article: Fetal tachyarrhythmias: current knowledge for clinical practice
Fetal tachyarrhythmias: current knowledge for clinical practice Open
Fetal arrhythmias account for 10-20% of all outpatient consultations in specialized fetal medicine centers. Furthermore, it is evident that tachyarrhythmias account for 8% of all such arrhythmias. Most arrhythmias are benign and easy to ma…
View article: Prenatal diagnosis of Apert syndrome with continuation of pregnancy—a report of two cases
Prenatal diagnosis of Apert syndrome with continuation of pregnancy—a report of two cases Open
These cases emphasize the importance of detailed fetal imaging, particularly in the third trimester, and the role of genetic testing in confirming syndromic craniosynostoses. Prenatal diagnosis of Apert syndrome enables early parental coun…
View article: Severe Maternal Morbidity and near Miss-Events in Women with Heart Disease: Insights from a Cohort Study
Severe Maternal Morbidity and near Miss-Events in Women with Heart Disease: Insights from a Cohort Study Open
Background/Objectives: The maternal mortality ratio is one of the global health indicators, and cardiopathies are the leading indirect causes of maternal deaths. Proper management of pregnant women with heart disease is crucial, as the sev…
View article: Pessary for Prevention of Preterm Birth and Perinatal Mortality in Pregnancies with a Short Cervix: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Pessary for Prevention of Preterm Birth and Perinatal Mortality in Pregnancies with a Short Cervix: Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Objective: This systematic review and meta-analysis aimed to evaluate the efficacy of cervical pessaries in preventing perinatal mortality and extreme preterm birth in pregnancies characterized by a short cervix. Methods: The analysis incl…
View article: Improved Myocardial Function in Autoimmune-Mediated Fetal Complete Atrioventricular Block Following Dexamethasone and Intravenous Immunoglobulin: A Case Report
Improved Myocardial Function in Autoimmune-Mediated Fetal Complete Atrioventricular Block Following Dexamethasone and Intravenous Immunoglobulin: A Case Report Open
This case report describes a fetus diagnosed with complete atrioventricular block (CAVB) associated with positive maternal anti-Ro and anti-La antibodies, referred to our fetal cardiology unit at 25 weeks of gestation. The diagnosis of sys…
View article: Congenital Rubella Syndrome in the Post-Elimination Era: Why Vigilance Remains Essential
Congenital Rubella Syndrome in the Post-Elimination Era: Why Vigilance Remains Essential Open
Congenital Rubella Syndrome (CRS) results from maternal infection with the rubella virus during pregnancy, particularly in the first trimester, when the risk of vertical transmission and severe fetal damage is highest. CRS is characterized…
View article: Twin Reversed Arterial Perfusion (<scp>TRAP</scp>) Sequence Phenotypes: A Comprehensive Visual Analysis
Twin Reversed Arterial Perfusion (<span>TRAP</span>) Sequence Phenotypes: A Comprehensive Visual Analysis Open
Twin reversed arterial perfusion (TRAP) sequence is a rare and severe complication of monochorionic twins, occurring in approximately 1 in 35 000 pregnancies. It is characterized by the presence of a severely abnormal, nonviable acardiac t…
View article: Perinatal Outcomes Related to the Presence of a Nuchal Cord During Delivery: A Retrospective Cohort Study
Perinatal Outcomes Related to the Presence of a Nuchal Cord During Delivery: A Retrospective Cohort Study Open
Objective: To evaluate and compare whether the presence of a nuchal cord (NC) and its characteristics had a negative impact on perinatal outcomes during delivery. Methods: This was a retrospective cohort study that analyzed the medical rec…
View article: Impact of a national policy on congenital heart disease mortality in Brazil
Impact of a national policy on congenital heart disease mortality in Brazil Open
Objective: The objective of this study was to evaluate the impact of the implementation of a National Plan for the Assistance of Children with Congenital Heart Disease (CHD) in Brazil on infant mortality rates. Methods: This retrospective …
View article: Development of a Z-score equation for atrioventricular interval measurement by two-dimensional pulsed Doppler echocardiography in normal fetuses between 16 and 33+6 weeks of gestation
Development of a Z-score equation for atrioventricular interval measurement by two-dimensional pulsed Doppler echocardiography in normal fetuses between 16 and 33+6 weeks of gestation Open
Purpose: Fetal echocardiography is the primary diagnostic tool for assessing the atrioventricular (AV) time interval. Establishing a reference range for this parameter throughout pregnancy is essential for the early detection of potential …
View article: Intervention using the Robson classification as a tool to reduce cesarean section rates in six public hospitals in Brazil
Intervention using the Robson classification as a tool to reduce cesarean section rates in six public hospitals in Brazil Open
Objectives To analyze the effectiveness and safety of a multifaceted intervention to reduce cesarean section (CS) rates. Methods This interrupted time series study involved six public hospitals with pre-intervention CS rates>35 %. We colle…
View article: Maternal and Perinatal Outcomes in Pregnant Women with Cancer: A Single-Center Retrospective Cohort Study
Maternal and Perinatal Outcomes in Pregnant Women with Cancer: A Single-Center Retrospective Cohort Study Open
Objective: The aim of our study was to evaluate maternal and perinatal outcomes in pregnant women diagnosed with cancer and treated at a single referral center in Brazil. Methods: This retrospective cohort study analyzed medical records fr…
View article: Evaluation of Fetal Myocardial Contractility of Pre‐Existing Diabetes Mellitus by Three‐Dimensional Ultrasonography Using STIC and Vocal Methods
Evaluation of Fetal Myocardial Contractility of Pre‐Existing Diabetes Mellitus by Three‐Dimensional Ultrasonography Using STIC and Vocal Methods Open
Objective To evaluate global and ventricular myocardial contractility in fetuses of pregnant women with pre‐existing diabetes compared with normal fetuses using three‐dimensional (3D) ultrasound with the Virtual Organ Computer‐aided Analys…
View article: Fetal Gastroschisis: Review From Diagnosis to Delivery
Fetal Gastroschisis: Review From Diagnosis to Delivery Open
Gastroschisis is a rare congenital condition that is increasing in incidence, possibly due to new lifestyles of women. Prenatal diagnosis is almost always possible in the second trimester, and color Doppler may be helpful. Fetuses with gas…
View article: Prenatal care for twin pregnancies: analysis of maternal and neonatal morbidity and mortality
Prenatal care for twin pregnancies: analysis of maternal and neonatal morbidity and mortality Open
Objectives To analyze maternal and neonatal morbidity and mortality in twin pregnancies, associated with the quality of prenatal and labor care, through the level of adherence to recommended protocols. Methods This was a retrospective coho…