Giuseppe Boriani
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View article: Transforming atrial fibrillation management by targeting comorbidities and reducing atrial fibrillation burden: the 10th AFNET/EHRA consensus conference
Transforming atrial fibrillation management by targeting comorbidities and reducing atrial fibrillation burden: the 10th AFNET/EHRA consensus conference Open
Atrial fibrillation (AF) is a growing unmet medical need. To reduce its impact on patients’ lives, improvements in stroke prevention therapy, treatment of concomitant conditions, and rhythm control therapy are actively developed: Innovatio…
View article: Optimising Lipid-Lowering Therapy for Acute Coronary Syndrome using a Decision Support System: Insights from a Cluster Randomised Trial
Optimising Lipid-Lowering Therapy for Acute Coronary Syndrome using a Decision Support System: Insights from a Cluster Randomised Trial Open
Aims Lipid-lowering therapy (LLT) after acute coronary syndrome (ACS) typically follows stepwise intensification, delaying use of combination therapies and LDL-C goal attainment. We assessed whether access to a Decision Support System (DSS…
View article: Management of device-detected subclinical atrial fibrillation: a European Heart Rhythm Association survey
Management of device-detected subclinical atrial fibrillation: a European Heart Rhythm Association survey Open
Aims Device-detected subclinical atrial fibrillation (DDAF) is increasingly documented either with implantable cardiac electronic devices (CIED) or with consumer-based mobile or wearable monitors. We aimed to investigate phisician's reacti…
View article: Real-world use of direct oral anticoagulants in atrial fibrillation patients with moderate/severe chronic kidney disease: a propensity score matched analysis from the START registry
Real-world use of direct oral anticoagulants in atrial fibrillation patients with moderate/severe chronic kidney disease: a propensity score matched analysis from the START registry Open
Background Chronic kidney disease (CKD) often coexists in patients with atrial fibrillation (AF), worsening patients’ prognosis. Direct oral anticoagulants (DOACs) are increasingly used also in patients with AF and CKD, but limited evidenc…
View article: Effects of transvenous lead extraction on tricuspid regurgitation and right ventricular function assessed by echocardiography: a cohort study
Effects of transvenous lead extraction on tricuspid regurgitation and right ventricular function assessed by echocardiography: a cohort study Open
Background Transvenous lead extraction in patients with cardiac implantable electronic devices (CIED) may be potentially associated with tricuspid valve damage and cardiac wall injury. Data on tricuspid valve damage after transvenous lead …
View article: Impact of weight/BMI on clinical and bleeding events in 26 805 atrial fibrillation patients on edoxaban from the Global ETNA-AF Registry
Impact of weight/BMI on clinical and bleeding events in 26 805 atrial fibrillation patients on edoxaban from the Global ETNA-AF Registry Open
Aims Body weight and body mass index (BMI) influence anticoagulation management in atrial fibrillation (AF) in interaction with age/comorbidities. Methods and results The Global ETNA-AF programme collected data on AF patients receiving edo…
View article: Adherence to oral thromboprophylaxis in atrial fibrillation: an overview for clinicians
Adherence to oral thromboprophylaxis in atrial fibrillation: an overview for clinicians Open
In most patients with atrial fibrillation (AF), effective stroke prevention necessitates long-term (often lifelong) oral anticoagulant therapy (OAC). However, the effectiveness of OAC therapy in a clinical setting (i.e. outside the control…
View article: Implementation of new concise care pathways into a software tool to detect and manage comorbidities in older patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS project
Implementation of new concise care pathways into a software tool to detect and manage comorbidities in older patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS project Open
Keywords Atrial fibrillation • Multimorbidity • Software • Care pathways This Rapid Communication is linked to the Original Article 'Development of three-step holistic care pathways to detect and manage comorbidities in patients with atria…
View article: Clinical complexity in patients with atrial fibrillation: exploring differential risk profiles from European and Asian cohorts
Clinical complexity in patients with atrial fibrillation: exploring differential risk profiles from European and Asian cohorts Open
Aims Clinical complexity (CC) in atrial fibrillation (AF) reflects overlapping risk factors that raise vulnerability to both thromboembolism and bleeding. Ethnic differences in the expression of CC remain poorly characterized. Methods and …
View article: No Increase in Blood Pressure Assessed With the 24‐h Holter Monitoring in Patients With Episodic Migraine During Early Treatment With Anti‐<scp>CGRP</scp> Monoclonal Antibodies: A Prospective Observational Study (<scp>SAFHYPER</scp>)
No Increase in Blood Pressure Assessed With the 24‐h Holter Monitoring in Patients With Episodic Migraine During Early Treatment With Anti‐<span>CGRP</span> Monoclonal Antibodies: A Prospective Observational Study (<span>SAFHYPER</span>) Open
Background Migraine is associated with an increased cardiovascular risk, including hypertension. Anti‐calcitonin gene related peptide (CGRP) monoclonal antibodies (mAbs) are effective preventive treatments, but concerns have been raised ab…
View article: Heart failure in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III
Heart failure in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III Open
Aims Congestive heart failure (CHF) is often coexisting in patients with atrial fibrillation (AF), but the clinical epidemiology of this association is still uncertain. We aimed to analyse characteristics, management, and outcomes of patie…
View article: Case Report: Hidden in motion: a challenging aortic mass unveiled by 3D transesophageal echocardiography
Case Report: Hidden in motion: a challenging aortic mass unveiled by 3D transesophageal echocardiography Open
This case report describes a 76-year-old asymptomatic male with a highly mobile, elongated, and filamentous structure incidentally detected in the ascending aorta during routine echocardiographic evaluation. The nature of this mass was ini…
View article: 2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee
2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee Open
ESC Clinical Consensus Statements, developed under the auspices of the ESC Clinical Practice Guidelines Committee, evaluate and summarize available evidence with the aim of assisting health professionals in proposing the best diagnostic or…
View article: 2025 ESC/EACTS Guidelines for the management of valvular heart disease
2025 ESC/EACTS Guidelines for the management of valvular heart disease Open
International audience
View article: Access and reimbursement of ambulatory cardiac monitoring across Europe
Access and reimbursement of ambulatory cardiac monitoring across Europe Open
Ambulatory cardiac monitoring (ACM) allows long-term electrocardiogram (ECG) monitoring to detect arrhythmias with different modalities, ranging from short-term Holter monitoring (up to 48 h) to long-term continuous patch ECG monitors (up …
View article: Monitoring patients and asymptomatic carriers with hereditary transthyretin amyloidosis: regional protocol of Emilia-Romagna ATTR working group
Monitoring patients and asymptomatic carriers with hereditary transthyretin amyloidosis: regional protocol of Emilia-Romagna ATTR working group Open
Transthyretin amyloidosis (ATTR) is a rare disease caused by the extracellular accumulation of misfolded transthyretin (TTR) amyloid fibrils. ATTR can be either hereditary (ATTRv) or acquired (wtATTR). ATTRv is caused by a mutation in the …
View article: Recent-onset atrial fibrillation: challenges and opportunities
Recent-onset atrial fibrillation: challenges and opportunities Open
Atrial fibrillation (AF) is increasingly diagnosed early, close to its first occurrence due to: (i) increased public awareness with self-screening; (ii) health care initiatives including population screening and opportunistic case finding;…
View article: History of falls in patients with atrial fibrillation and risk of major outcomes: analysis from the Prospective GLORIA-AF Registry
History of falls in patients with atrial fibrillation and risk of major outcomes: analysis from the Prospective GLORIA-AF Registry Open
Falls pose concerns for the management and prognosis of patients with atrial fibrillation (AF). Epidemiological data on patients with AF who fall are limited. From the prospective global GLORIA-AF Registry Phase III study, we evaluated pat…
View article: Real-World Use of ARNI Within GDMT in HFrEF Patients with and Without Atrial Fibrillation: A Retrospective Analysis of Cardiac and Renal Functions and Clinical Outcomes
Real-World Use of ARNI Within GDMT in HFrEF Patients with and Without Atrial Fibrillation: A Retrospective Analysis of Cardiac and Renal Functions and Clinical Outcomes Open
The aim of this study was to describe changes in estimated glomerular filtration rate (eGFR), left ventricular ejection fraction (LVEF) and clinical outcomes in a real-world cohort of patients with heart failure with reduced ejection fract…
View article: Vitamin D insufficiency and cardiovascular involvement in systemic sclerosis: Association with echocardiographic parameters and risk factors
Vitamin D insufficiency and cardiovascular involvement in systemic sclerosis: Association with echocardiographic parameters and risk factors Open
Vitamin D insufficiency may contribute to cardiovascular dysfunction in SSc patients. Monitoring vitamin D levels might improve cardiovascular risk stratification. Further studies are necessary to determine if supplementation could enhance…
View article: Cost-effectiveness of atrial fibrillation screening programmes across European nations
Cost-effectiveness of atrial fibrillation screening programmes across European nations Open
Aims Due to the ageing population in Europe, a significant increase in the incidence of atrial fibrillation (AF) is anticipated. This is predicted to have a detrimental impact on public health costs, particularly among the elderly, because…