Chaitawat Sirisereewan
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View article: Mitochondrial dysfunction in PRRSV-2-infected macrophages
Mitochondrial dysfunction in PRRSV-2-infected macrophages Open
Introduction Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically devastating viruses for the global swine industry. PRRSV has a known tropism for lung macrophages, where it causes impaired immune res…
View article: Establishment of Immune Biobank for Vaccine Immunogenicity Prediction Using In Vitro and In Silico Methods Against Porcine Reproductive and Respiratory Syndrome Virus
Establishment of Immune Biobank for Vaccine Immunogenicity Prediction Using In Vitro and In Silico Methods Against Porcine Reproductive and Respiratory Syndrome Virus Open
Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most economically significant pathogens in the global swine industry. Despite the availability of commercial vaccines for over three deca…
View article: Comparative evaluation of PRRSV MLV vaccine efficacy administered via intranasal and intramuscular routes in early age of piglets
Comparative evaluation of PRRSV MLV vaccine efficacy administered via intranasal and intramuscular routes in early age of piglets Open
Early porcine reproductive and respiratory syndrome virus (PRRSV) infections in suckling pigs are commonly observed, emphasizing the need for early vaccination strategies. However, the effectiveness of early vaccination in suckling pigs re…
View article: First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand
First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand Open
Atypical Porcine Pestivirus (APPV) is an emerging pathogen in pigs. The virus causes diseases associated with neurological disorders, such as congenital tremors (CT) Type A-II in piglets, leading to economic losses in the swine industry. T…
View article: Differential Effects of Selenium Compounds on Mitochondrial Function in PRRSV-Infected Porcine Alveolar Macrophages
Differential Effects of Selenium Compounds on Mitochondrial Function in PRRSV-Infected Porcine Alveolar Macrophages Open
Selenium (Se) is a trace mineral with antioxidant and anti-inflammatory properties. Se deficiency increases oxidative stress and immunosuppression. In swine, dietary Se supplementation enhances immunity and growth, and previous studies sug…
View article: Analysis of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Interactome
Analysis of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Interactome Open
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen that causes significant economic losses worldwide. The nucleocapsid (N) protein, the most abundant viral protein in infected cells, plays roles beyond it…
View article: Establishment of Immune Biobank for Vaccine Immunogenicity Prediction Using <em>In Vitro</em> and <em>In Silico</em> Methods Against Porcine Reproductive and Respiratory Syndrome Virus
Establishment of Immune Biobank for Vaccine Immunogenicity Prediction Using <em>In Vitro</em> and <em>In Silico</em> Methods Against Porcine Reproductive and Respiratory Syndrome Virus Open
Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most economically significant pathogens in the global swine industry. Despite the availability of commercial vaccines for over three deca…
View article: Differential Effects of Selenium Compounds on Mitochondrial Function in PRRSV-Infected Porcine Alveolar Macrophages
Differential Effects of Selenium Compounds on Mitochondrial Function in PRRSV-Infected Porcine Alveolar Macrophages Open
Selenium (Se) is an essential trace mineral with antioxidant and anti-inflammatory properties. Se deficiency increases oxidative stress and immunosuppression. In swine, dietary Se supplementation enhances immune function and growth, and pr…
View article: Challenges and Lessons Learned from a Field Trial on the Understanding of the Porcine Respiratory Disease Complex
Challenges and Lessons Learned from a Field Trial on the Understanding of the Porcine Respiratory Disease Complex Open
The Porcine Respiratory Disease Complex (PRDC) is a multifaceted, polymicrobial syndrome resulting from a combination of environmental stressors, primary infections (e.g., PRRSV) and secondary infectious agents (viruses and bacteria). PRDC…
View article: Comparison of Vaccination Regimens on Immune Responses Using PED Replicon Vaccine: A Field Trial in PED-Negative and PED-Positive Thai Swine Farms
Comparison of Vaccination Regimens on Immune Responses Using PED Replicon Vaccine: A Field Trial in PED-Negative and PED-Positive Thai Swine Farms Open
Porcine epidemic diarrhea virus (PEDV) is an economically important pathogen of swine, causing severe diarrhea in neonates with high morbidity and mortality. Vaccination is a key strategy for PEDV control, but optimizing regimens based on …
View article: Comparative Evaluation of Prrsv Mlv Vaccine Efficacy Administered Via Intranasal and Intramuscular Routes in Early Age of Piglets
Comparative Evaluation of Prrsv Mlv Vaccine Efficacy Administered Via Intranasal and Intramuscular Routes in Early Age of Piglets Open
View article: Enhancement of Systemic Virus-Specific T Lymphocyte Responses in Pigs Supplemented with Algae-Derived Β-Glucan
Enhancement of Systemic Virus-Specific T Lymphocyte Responses in Pigs Supplemented with Algae-Derived Β-Glucan Open
View article: Emergence of novel porcine circovirus 2d strains in Thailand, 2019–2020
Emergence of novel porcine circovirus 2d strains in Thailand, 2019–2020 Open
Porcine circovirus 2 (PCV2) has been recognized as a causative agent of porcine circovirus diseases (PCVDs) affecting the global swine industry. In this study, the genetic diversity of PCV2 strains circulating in Thailand between 2019 and …
View article: Molecular detection and genetic characterization of porcine circovirus 4 (PCV4) in Thailand during 2019–2020
Molecular detection and genetic characterization of porcine circovirus 4 (PCV4) in Thailand during 2019–2020 Open
View article: Emergence of a novel recombinant porcine circovirus type 2b (PCV2b) and PCV2d in Thailand
Emergence of a novel recombinant porcine circovirus type 2b (PCV2b) and PCV2d in Thailand Open
Porcine circovirus type 2 (PCV2) has been recognized as a causative agent of porcine circovirus-associated diseases (PCVAD) affecting the global swine industry for more than three decades. The high mutation rate of PCV2 can lead to rapid e…
View article: Current Understanding of the Pathogenesis of Porcine Circovirus 3
Current Understanding of the Pathogenesis of Porcine Circovirus 3 Open
Circoviruses are closed, circular, single-stranded DNA viruses belonging to the family Circoviridae and the genus Circovirus. To date, at least four porcine circoviruses (PCVs) have been recognized, including PCV1 to PCV4, respectively. Si…
View article: Major swine viral diseases: an Asian perspective after the African swine fever introduction
Major swine viral diseases: an Asian perspective after the African swine fever introduction Open
Asia is a major pig producer of the world, and at present, African swine fever virus (ASFV) continues to significantly impact the Asian pig industry. Since more than 50% of the world’s pig population is in Asia, ASFV outbreaks in Asia will…
View article: Dual infection of a Thai isolate HP-PRRSV and the pdmH1N1 2009 SIV in weanling pigs
Dual infection of a Thai isolate HP-PRRSV and the pdmH1N1 2009 SIV in weanling pigs Open
After the introduction of the pandemic H1N1 swine influenza virus (pdmH1N1 SIV) in Thai swine farms in 2009, a mild clinical outcome was observed and its role in porcine respiratory disease complex (PRDC) is questionable. A highly pathogen…
View article: Detection of PRRSV circulation using oral fluid samples for nursery management in endemically PRRSV-infected farms
Detection of PRRSV circulation using oral fluid samples for nursery management in endemically PRRSV-infected farms Open
Porcine reproductive and respiratory syndrome (PRRS) has become a major swine disease worldwide. Relevant management strategies and diagnostic assays are of importance for PRRS virus (PRRSV) control. The objective of this study was to dete…
View article: EFFECTS OF DNA-MLV PRIME BOOST IMMUNIZATION ON MODULATION OF PRRSV-SPECIFIC IMMUNE RESPONSES IN HP-PRRSV CHALLENGED PIGS
EFFECTS OF DNA-MLV PRIME BOOST IMMUNIZATION ON MODULATION OF PRRSV-SPECIFIC IMMUNE RESPONSES IN HP-PRRSV CHALLENGED PIGS Open
Porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized as the important swine pathogen that threaten swine industry globally. The quasispesies character of PRRSV causes genetic variation, leading to the emergence o…