Changhao Liu
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View article: A Novel Strategy for Soft Tissue Sarcoma Lattice Radiotherapy: Integrating X-Ray andγ-Ray Technologies to Optimize Dose Delivery
A Novel Strategy for Soft Tissue Sarcoma Lattice Radiotherapy: Integrating X-Ray andγ-Ray Technologies to Optimize Dose Delivery Open
Background: The TaiChi radiotherapy platform is an innovative system integrating linear accelerator (LINAC) and Gamma Knife technologies, approved by both NMPA and FDA. This hybrid design enables bimodal (X-ray and γ-ray) radiation deliver…
View article: Prediction of Distant Metastasis in Head and Neck Cancer Patients Using Tumor and Peritumoral Multi-Modal Deep Learning
Prediction of Distant Metastasis in Head and Neck Cancer Patients Using Tumor and Peritumoral Multi-Modal Deep Learning Open
Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment fa…
View article: Long-term trends and projections of ovarian cancer burden in China (1990 to 2040): an age-period-cohort analysis based on GBD 2021 data
Long-term trends and projections of ovarian cancer burden in China (1990 to 2040): an age-period-cohort analysis based on GBD 2021 data Open
Background The growing burden of ovarian cancer is attracting widespread attention; the impact factors and the evolution trend of ovarian cancer burden need to be further studied. Methods Ovarian cancer disease burden data for Chinese wome…
View article: Neck muscle training improving the setup of reproducibility in patient with head and neck cancer receiving radiotherapy - a prospective randomized controlled study
Neck muscle training improving the setup of reproducibility in patient with head and neck cancer receiving radiotherapy - a prospective randomized controlled study Open
View article: Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers: a prospective randomized controlled trial
Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers: a prospective randomized controlled trial Open
In head and neck cancer radiotherapy, we propose the idea of personalized open-face mask combined with styrofoam for the first time, which can improve patient comfort without sacrificing positioning accuracy, and has a tendency to relieve …
View article: Author Correction: Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation
Author Correction: Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation Open
View article: Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation
Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation Open
View article: Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers: A prospective randomized controlled trial
Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers: A prospective randomized controlled trial Open
Objective The primary aim of this investigation is to assess the effectiveness of implementing an innovative immobilization approach, spec ically the utilization of personalized open-face masks in combination with styrofoam fixation, for h…
View article: Prognostic Impact of Tumor-Infiltrating Immune Cells on Efficacy of Neoadjuvant Chemotherapy in Patients with Advanced or Metastatic Ovarian Cancer: A Retrospective Study
Prognostic Impact of Tumor-Infiltrating Immune Cells on Efficacy of Neoadjuvant Chemotherapy in Patients with Advanced or Metastatic Ovarian Cancer: A Retrospective Study Open
BACKGROUND Tumor-infiltrating immune cells (TIICs) are implicated in the survival of ovarian cancer (OVCA) patients, but their prognostic significance in advanced or metastatic OVCA patients treated with neoadjuvant chemotherapy (NCAT) has…
View article: A survey on brachytherapy training of gynecological cancer focusing on the competence of residents in China
A survey on brachytherapy training of gynecological cancer focusing on the competence of residents in China Open
Background The brachytherapy is an indispensable treatment for gynecological tumors, but the quality and efficiency of brachytherapy training for residents is still unclear. Methods An anonymous questionnaire was designed to collect inform…
View article: Selection of treatment strategies for lumbar Brucella spondylitis: a retrospective clinical study
Selection of treatment strategies for lumbar Brucella spondylitis: a retrospective clinical study Open
Objective This study aims to investigate the treatment strategies for lumbar brucellar spondylitis by comparing the outcomes of pure pharmacological treatment with diseased intervertebral fixation fusion, with or without lesion clearance. …
View article: A survey on brachytherapy training of gynecological cancer focusing on the competence of residents in China.
A survey on brachytherapy training of gynecological cancer focusing on the competence of residents in China. Open
Background: the brachytherapy is an indispensable treatment for gynecological tumors, but the quality and efficiency of brachytherapy training for residents is still unclear. Methods: An anonymous questionnaire was designed to collect info…
View article: Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities
Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities Open
View article: Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition
Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition Open
Cytoskeletal reorganization and epithelial-to-mesenchymal transition (EMT) are key processes and typical characteristics of metastatic cancer cells. Rho GTPase‑activating protein 35 (ARHGAP35) is a GTPase-activating protein, which has a si…
View article: Retraction Note: Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta‑analysis
Retraction Note: Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta‑analysis Open
View article: AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway
AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway Open
Osteosarcoma is a primary bone tumor that mainly occurs in children and adolescents. Absent in melanoma 2 (AIM2) has been demonstrated to be involved in regulating the occurrence and development of cancer, exerting oncogenic and pro‑cancer…
View article: Prognostic impact of hepatitis B virus infection in patients with primary cervical cancer
Prognostic impact of hepatitis B virus infection in patients with primary cervical cancer Open
Background Hepatitis B virus (HBV) infection has been associated with an increased risk of a few malignancies. However, the prognostic impact of HBV infection remains unclear in cervical cancer. Objective To explore the association between…
View article: Development and validation of a discrimination model between primary PLA2R-negative membranous nephropathy and minimal change disease confirmed by renal biopsy
Development and validation of a discrimination model between primary PLA2R-negative membranous nephropathy and minimal change disease confirmed by renal biopsy Open
View article: The integration of bevacizumab improves tumor response and survival in patients with refractory cervical cancer treated with radical chemoradiotherapy
The integration of bevacizumab improves tumor response and survival in patients with refractory cervical cancer treated with radical chemoradiotherapy Open
Bevacizumab combined with radical chemoradiotherapy is a safe and tolerable treatment option for refractory CC, with quicker tumor regression and high OS, locoregional relapse-free survival, and distant metastasis-free survival rates.
View article: Sporophytic control of anther development and male fertility by glucose-6-phosphate/phosphate translocator 1 (OsGPT1) in rice
Sporophytic control of anther development and male fertility by glucose-6-phosphate/phosphate translocator 1 (OsGPT1) in rice Open
Coordination between the sporophytic tissue and the gametic pollen within anthers is tightly controlled to achieve the optimal pollen fitness. Glucose-6-phosphate/phosphate translocator (GPT) transports glucose-6-phosphate, a key precursor…
View article: Prognostic analysis of 152 patients with distant metastasis after intensity-modulated radiotherapy for nasopharyngeal carcinoma
Prognostic analysis of 152 patients with distant metastasis after intensity-modulated radiotherapy for nasopharyngeal carcinoma Open
The prognosis of NPC patients with distant metastasis after IMRT was related to the time from radiotherapy completion to distant metastasis, liver and multi-organ metastasis, and whether adjuvant chemotherapy was administered. Both adequat…
View article: Selection of the fusion and fixation range in the intervertebral surgery to correct thoracolumbar and lumbar tuberculosis: a retrospective clinical study
Selection of the fusion and fixation range in the intervertebral surgery to correct thoracolumbar and lumbar tuberculosis: a retrospective clinical study Open
View article: Chondroblastoma of the patella with secondary aneurysmal bone cyst, an easily misdiagnosed bone tumor:a case report with literature review
Chondroblastoma of the patella with secondary aneurysmal bone cyst, an easily misdiagnosed bone tumor:a case report with literature review Open
Background Chondroblastoma (CB) is a rare, primary, benign bone tumor that commonly affects men aged 15–20 years. It is usually detected in the epiphysis of the long bones, such as the proximal femur, humerus, and tibia. The patella is an …
View article: Development and Validation of a Between Primary PLA2R-Negative Membranous Nephropathy and Minimal Change Disease Confirmed by Renal Biopsy
Development and Validation of a Between Primary PLA2R-Negative Membranous Nephropathy and Minimal Change Disease Confirmed by Renal Biopsy Open
Background: Membranous nephropathy (MN) and minimal change disease (MCD) are two common causes leading to nephrotic syndrome (NS). They have similar clinical feature but different treatment strategy and prognosis. M-type phospholipase A2 r…
View article: Application value of combination therapy of periodontal curettage and root planing on moderate-to-severe chronic periodontitis in patients with type 2 diabetes
Application value of combination therapy of periodontal curettage and root planing on moderate-to-severe chronic periodontitis in patients with type 2 diabetes Open
Background Our study attempted to observe the value of periodontal curettage combined with root planing on moderate-to-severe chronic periodontitis in patients with type 2 diabetes. Methods There involved 72 patients with type 2 diabetes m…
View article: Selection of the Fusion and Fixation Range in the Intervertebral Surgery to Correct Thoracolumbar and Lumbar Tuberculosis：A Retrospective Clinical Study
Selection of the Fusion and Fixation Range in the Intervertebral Surgery to Correct Thoracolumbar and Lumbar Tuberculosis：A Retrospective Clinical Study Open
Background To compare the diseased verses the non-diseased intervertebral surgery used in the treatment of thoracolumbar and lumbar spinal tuberculosis and to explore the best choice of fusion of fixation range. Methods 221 patients with t…
View article: Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis
Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis Open
View article: Knockdown of 91 H Suppresses the Tumorigenesis of Osteosarcoma via Inducing Methylation of CDK4 Promoter
Knockdown of 91 H Suppresses the Tumorigenesis of Osteosarcoma via Inducing Methylation of CDK4 Promoter Open
Background: Osteosarcoma is the most leading primary malignancy of the bone in adolescents all over the world. Long non-coding RNA (lncRNA) 91 H has been reported to participated in multiple cancers. Meanwhile, lncRNA 91 H has been proved …
View article: Development and Validation of a Discrimination Model Between Primary PLA2R-Negative Membranous Nephropathy and Minimal Change Disease Confirmed by Renal Biopsy
Development and Validation of a Discrimination Model Between Primary PLA2R-Negative Membranous Nephropathy and Minimal Change Disease Confirmed by Renal Biopsy Open
BackgroundMembranous nephropathy (MN) and minimal change disease (MCD) are two common causes leading to nephrotic syndrome (NS). They have similar clinical feature but different treatment strategy and prognosis. M-type phospholipase A2 rec…
View article: The necessity of treating asymptomatic bacteriuria with antibiotics in the perioperative period of joint arthroplasty: a metaanalysis
The necessity of treating asymptomatic bacteriuria with antibiotics in the perioperative period of joint arthroplasty: a metaanalysis Open
The occurrence of asymptomatic bacteriuria in the perioperative period of joint arthroplasty is a risk factor for periprosthetic joint infection, and the use of antibiotics for asymptomatic bacteriuria does not change the rate of incidence.