Changmin Yu
YOU?
Author Swipe
View article: Denosumab usage is associated with better overall survival of patients with lung cancer and bone metastases: a retrospective cohort study
Denosumab usage is associated with better overall survival of patients with lung cancer and bone metastases: a retrospective cohort study Open
Background Lung cancer with progressive bone metastases usually leads to skeletal-related events (SREs) and a reduced quality of life. Denosumab delays the onset of SREs and is associated with improved overall survival. However, other fact…
View article: Hippocampal theta sweeps indicate goal direction
Hippocampal theta sweeps indicate goal direction Open
Successful spatial navigation requires rapid evaluation of potential future trajectories. Hippocampal “theta sweeps”, sequential activation of place cells within individual theta cycles, exhibit predictive dynamics within the ideal timefra…
View article: From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life
From experimental clues to theoretical modeling: Evolution associated with the membrane-takeover at an early stage of life Open
Modern cell membranes are primarily composed of phospholipids, while primitive cell membranes in the beginning of life are believed to have formed from simpler lipids (such as fatty acids) synthesized in the prebiotic environment. An attra…
View article: Correction: Carbon-dot-based ratiometric fluorescent sensor for detecting hydrogen sulfide in aqueous media and inside live cells
Correction: Carbon-dot-based ratiometric fluorescent sensor for detecting hydrogen sulfide in aqueous media and inside live cells Open
Correction for ‘Carbon-dot-based ratiometric fluorescent sensor for detecting hydrogen sulfide in aqueous media and inside live cells’ by Changmin Yu et al. , Chem. Commun. , 2013, 49 , 403–405, https://doi.org/10.1039/C2CC37329G.
View article: Dynamical Modulation of Hippocampal Replay Sequences through Firing Rate Adaptation
Dynamical Modulation of Hippocampal Replay Sequences through Firing Rate Adaptation Open
During periods of immobility and sleep, the hippocampus generates diverse self-sustaining sequences of “replay” activity, exhibiting stationary, diffusive, and super-diffusive dynamical patterns. However, the neural mechanisms underlying t…
View article: Clinical application of FIGO 2023 staging system of endometrial cancer in a Chinese cohort
Clinical application of FIGO 2023 staging system of endometrial cancer in a Chinese cohort Open
Objective: The International Federation of Gynecology and Obstetrics (FIGO) 2023 staging system represents a refined classification with a comprehensive and improved prognostic significance for endometrial cancer (EC). Our objective is to …
View article: Outside Back Cover: Volume 5 Issue 3
Outside Back Cover: Volume 5 Issue 3 Open
Outside back cover image: β-Lactamase represents a significant contributor to the challenge of antibiotic resistance, rendering detection a critical priority in point-of-care testing. Herein, an artificial intelligence-assisted mobile heal…
View article: Current and Future of “Turn‐On” Based Small‐Molecule Copper Probes for Cuproptosis
Current and Future of “Turn‐On” Based Small‐Molecule Copper Probes for Cuproptosis Open
Increasing evidence shows that abnormal copper (Cu) metabolism is highly related to many diseases, such as Alzheimer's disease, Wilson's disease, hematological malignancies and Menkes disease. Very recently, cuproptosis, a Cu‐dependent, pr…
View article: Artificial intelligence‐assisted point‐of‐care testing system for ultrafast and quantitative detection of drug‐resistant bacteria
Artificial intelligence‐assisted point‐of‐care testing system for ultrafast and quantitative detection of drug‐resistant bacteria Open
As one of the major causes of antimicrobial resistance, β‐lactamase develops rapidly among bacteria. Detection of β‐lactamase in an efficient and low‐cost point‐of‐care testing (POCT) way is urgently needed. However, due to the volatile en…
View article: Label‐Free Fluorescence Turn‐On Detection of Histidine‐Tagged Proteins Based on Intramolecular Rigidification Induced Emission
Label‐Free Fluorescence Turn‐On Detection of Histidine‐Tagged Proteins Based on Intramolecular Rigidification Induced Emission Open
Histidine tag (His‐tag) is a representative epitope tag, which has been widely used in the purification or immobilization of recombinant proteins. In this study, a novel probe CTPE‐IDA‐Ni 2+ based on intramolecular rigidification induced e…
View article: Vitamin B12 Ameliorates the Pathological Phenotypes of Multiple Parkinson’s Disease Models by Alleviating Oxidative Stress
Vitamin B12 Ameliorates the Pathological Phenotypes of Multiple Parkinson’s Disease Models by Alleviating Oxidative Stress Open
Parkinson’s disease (PD) is the second most common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra of the midbrain. The etiology of PD has yet to be elucidated, and the disease re…
View article: A light-activated magnetic bead strategy utilized in spatio-temporal controllable exosomes isolation
A light-activated magnetic bead strategy utilized in spatio-temporal controllable exosomes isolation Open
Tumor-derived exosomes are considered as a key biomarker in the field of liquid biopsy. However, conventional separation techniques such as ultracentrifugation, co-precipitation and column chromatography cannot isolate samples with high th…
View article: Small-molecule fluorescent probes based on covalent assembly strategy for chemoselective bioimaging
Small-molecule fluorescent probes based on covalent assembly strategy for chemoselective bioimaging Open
In this review, we comprehensively summarize the recent progress in the development of small molecular fluorescent probes based on the covalent assembly principle. The challenges and perspective in this field are also presented.
View article: Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics
Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics Open
Sweat contains a broad range of critical biomarkers including ions, small molecules, and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression. Wearable sweat …
View article: Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues
Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues Open
Monoamine oxidases have two functionally distinct but structurally similar isoforms (MAO‐A and MAO‐B). The ability to differentiate them by using fluorescence detection/imaging technology is of significant biological relevance, but highly …
View article: Cover Feature: Fast‐Response Fluorogenic Probe for Visualizing Hypochlorite in Living Cells and in Zebrafish (ChemBioChem 6/2019)
Cover Feature: Fast‐Response Fluorogenic Probe for Visualizing Hypochlorite in Living Cells and in Zebrafish (ChemBioChem 6/2019) Open
The cover feature picture shows a Chinese scientist standing on a survey ship with binoculars watching the meteors of the North Pole night. Under these extreme conditions, the meteors change from dull to dazzling yellow as they pass throug…