Long Chen
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View article: Transcriptomic analysis reveals cell wall polysaccharide metabolism associated with post-harvest softening in shiitake mushrooms (Lentinula edodes)
Transcriptomic analysis reveals cell wall polysaccharide metabolism associated with post-harvest softening in shiitake mushrooms (Lentinula edodes) Open
View article: Comprehensive pan-cancer evaluation of NUP85 prognosis, immune infiltration response, and validation in prostate cancer
Comprehensive pan-cancer evaluation of NUP85 prognosis, immune infiltration response, and validation in prostate cancer Open
The results indicate that elevated NUP85 expression shows strong correlations with cancer initiation and progression. These findings support its potential utility as a candidate biomarker for disease monitoring across various malignancies,…
View article: Dynamic Self‐Optimizing Interfaces via Cu Corrosion and Anion‐Vacancy Synergy in SnSSe @ Recycled Graphite Anodes for High‐Performance Sodium‐Ion Batteries
Dynamic Self‐Optimizing Interfaces via Cu Corrosion and Anion‐Vacancy Synergy in SnSSe @ Recycled Graphite Anodes for High‐Performance Sodium‐Ion Batteries Open
Tin sulfide (SnS 2 ) anodes for sodium‐ion batteries (SIBs) exhibit high theoretical capacity (1136 mAh g −1 ) but face sluggish kinetics and structural instability due to volume expansion and poor conductivity. This work proposes a dual‐d…
View article: Efficacy and safety of linezolid versus vancomycin for the treatment of central nervous system infections: a meta-analysis
Efficacy and safety of linezolid versus vancomycin for the treatment of central nervous system infections: a meta-analysis Open
View article: Association of Diaphragm Involvement Assessed by Ultrasound With Disease Severity in Facioscapulohumeral Muscular Dystrophy
Association of Diaphragm Involvement Assessed by Ultrasound With Disease Severity in Facioscapulohumeral Muscular Dystrophy Open
Background Respiratory involvement is a comorbidity that should not be overlooked in clinical practice in facioscapulohumeral muscular dystrophy type 1 (FSHD1), with a reported association for severe disease outcomes such as wheelchair dep…
View article: Enhanced vitamin B6 production in engineered Escherichia coli via restricted mix-carbon feeding and pressure-controlled fermentation
Enhanced vitamin B6 production in engineered Escherichia coli via restricted mix-carbon feeding and pressure-controlled fermentation Open
Pyridoxine (PN), a major commercial form of vitamin B6, is mainly produced via chemical synthesis, raising environmental concerns. Microbial fermentation offers a greener alternative, but low biomass and titer limit industrial application.…
View article: Biomechanical effects of six internal fixation methods for distal femoral AO/OTA 33C1 fractures: finite element analysis
Biomechanical effects of six internal fixation methods for distal femoral AO/OTA 33C1 fractures: finite element analysis Open
View article: Programmable skyrmions for robust communication and intelligent sensing
Programmable skyrmions for robust communication and intelligent sensing Open
The recently observed plasmonic skyrmions, as electromagnetic counterparts of topologically stable quasiparticles, hold significant promise as novel carriers for robust information transfer and manipulation of nontrivial light-matter inter…
View article: 753 | FINAL ANALYSIS OF CONCORDANCE STUDY OF IMMUNOHISTOCHEMICAL CD30 EXPRESSION DETECTED BY NINE ASSAYS AND THE VENTANA CD30 ASSAY IN CHINESE LYMPHOMA PATIENTS (CREDIT STUDY)
753 | FINAL ANALYSIS OF CONCORDANCE STUDY OF IMMUNOHISTOCHEMICAL CD30 EXPRESSION DETECTED BY NINE ASSAYS AND THE VENTANA CD30 ASSAY IN CHINESE LYMPHOMA PATIENTS (CREDIT STUDY) Open
View article: 762 | ARTIFICIAL INTELLIGENCE‐ASSISTED QUANTITATIVE ANALYSIS FOR THE IMMUNOHISTOCHEMICAL EXPRESSION OF CD30 IN LYMPHOMAS
762 | ARTIFICIAL INTELLIGENCE‐ASSISTED QUANTITATIVE ANALYSIS FOR THE IMMUNOHISTOCHEMICAL EXPRESSION OF CD30 IN LYMPHOMAS Open
View article: The U-curve associations of birth interval with prevalence of osteoarthritis in postmenopausal women
The U-curve associations of birth interval with prevalence of osteoarthritis in postmenopausal women Open
AFB, ALB and birth interval shown the U-shaped associations with OA prevalence in postmenopausal women with two deliveries. These findings highlight the potential long-term impacts of reproductive history on musculoskeletal health and may …
View article: Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration Open
Background Intervertebral disc degeneration (IDD) significantly contributes to low back pain (LBP), yet effective treatment options are scarce. BSHXF, a classical traditional Chinese medicine formula, demonstrates dual pharmacological acti…
View article: Mimicking nature's synergy: engineering FN3-based protein scaffolds for multi-enzyme assembly
Mimicking nature's synergy: engineering FN3-based protein scaffolds for multi-enzyme assembly Open
Multi-enzyme cascade reactions are common in nature. Compared to free-floating enzyme catalysis, enzyme co-localization, existing in some natural systems, can improve the efficiency of the reactions thanks to kinetic benefits. In engineeri…
View article: Comparison of the clinical outcomes and radiological parameters between the greater tuberosity strengthened proximal humeral plate and the proximal humeral internal locking system plate in the minimally invasive plate osteosynthesis treatment of proximal humeral fractures involving the greater tuberosity: a retrospective cohort study
Comparison of the clinical outcomes and radiological parameters between the greater tuberosity strengthened proximal humeral plate and the proximal humeral internal locking system plate in the minimally invasive plate osteosynthesis treatment of proximal humeral fractures involving the greater tuberosity: a retrospective cohort study Open
View article: Comparison of Patellar Tracking Following Kinematic Alignment Versus Mechanical Alignment Total Knee Arthroplasty via the Mini‐Subvastus Approach
Comparison of Patellar Tracking Following Kinematic Alignment Versus Mechanical Alignment Total Knee Arthroplasty via the Mini‐Subvastus Approach Open
Objectives Different alignment strategies (kinematic alignment [KA] versus mechanical alignment [MA]) during total knee arthroplasty (TKA) significantly influence postoperative patellar tracking. This study aimed to compare radiological pa…
View article: LncRNA MEG3 suppresses prostate cancer progression by mediating macrophage polarization via the miR-148a-3p/ARRDC3 signaling axis
LncRNA MEG3 suppresses prostate cancer progression by mediating macrophage polarization via the miR-148a-3p/ARRDC3 signaling axis Open
Long-chain noncoding RNA (LncRNA) MEG3 significantly influences tumor microenvironment (TME) dynamics and macrophage polarization. However, its specific involvement in prostate cancer (PCa) progression remains unclear. MEG3 exhibited low e…
View article: Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1
Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1 Open
Ginsenoside Rg5 exerts a protective effect against radiation-induced endothelial injury by modulating mitochondrial dynamics and function, as well as maintaining endothelial barrier integrity, in a Sirt1-dependent manner.
View article: Effect of perampanel in reducing depression in patients with focal epilepsy
Effect of perampanel in reducing depression in patients with focal epilepsy Open
Perampanel reduced depression symptoms in patients with focal epilepsy, although the lack of a control group or the relatively small sample size.
View article: Integrated single-cell and bulk transcriptome analysis of R-loop score-based signature with regard to immune microenvironment, lipid metabolism and prognosis in HCC
Integrated single-cell and bulk transcriptome analysis of R-loop score-based signature with regard to immune microenvironment, lipid metabolism and prognosis in HCC Open
Background Hepatocellular carcinoma (HCC) is one of the most prevalent causes of cancer-related morbidity and mortality worldwide. Late-stage detection and the complex molecular mechanisms driving tumor progression contribute significantly…
View article: Corrigendum to “Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signaling pathways” [Ecotoxicol. Environ. Saf. 286 (2024) 117185]
Corrigendum to “Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signaling pathways” [Ecotoxicol. Environ. Saf. 286 (2024) 117185] Open
View article: Study on the Effect of Longan Endophyte Fermentation broth on the Storage Quality of Passion Fruit
Study on the Effect of Longan Endophyte Fermentation broth on the Storage Quality of Passion Fruit Open
View article: Detection and Antimicrobial Susceptibility of Carbapenem‐Resistant Organisms Isolated in the Center of Care and Protection of Orphan Children, Vietnam
Detection and Antimicrobial Susceptibility of Carbapenem‐Resistant Organisms Isolated in the Center of Care and Protection of Orphan Children, Vietnam Open
Carbapenems are critical for treating patients infected with multidrug‐resistant bacteria; however, the use of carbapenems has also facilitated the selection and spreading of carbapenem‐resistant organisms (CROs), occasionally reported in …
View article: Modified kinematic alignment better restores plantar pressure distribution than mechanical alignment in total knee arthroplasty: a randomized controlled trial
Modified kinematic alignment better restores plantar pressure distribution than mechanical alignment in total knee arthroplasty: a randomized controlled trial Open
View article: TQB2450 with or without anlotinib as maintenance treatment in subjects with locally advanced/unresectable non-small cell lung cancer that have not progressed after prior concurrent/sequential chemoradiotherapy (R-ALPS): study protocol for a randomized, double-blind, placebo-controlled, multicenter phase III trial
TQB2450 with or without anlotinib as maintenance treatment in subjects with locally advanced/unresectable non-small cell lung cancer that have not progressed after prior concurrent/sequential chemoradiotherapy (R-ALPS): study protocol for a randomized, double-blind, placebo-controlled, multicenter phase III trial Open
Clinicaltrials.gov identifier: NCT04325763. Date of registration: May 27, 2020. Protocol version: Version 4.0, Sep 16, 2022 (https://classic.clinicaltrials.gov/ct2/show/NCT04325763).
View article: Use of a 2/3 Free Vascularized Fibula Flap for Tibiofibular Bone Defect Reconstruction
Use of a 2/3 Free Vascularized Fibula Flap for Tibiofibular Bone Defect Reconstruction Open
Case: A 40-year-old man with a tibiofibular bone defect caused by infection was treated using a 2/3 free vascularized fibula flap, which preserved 1/3 of the continuous periosteum and cortex of the fibula at the donor site, allowing for re…
View article: Natural Ginger Extract Versus Curcumin: Who Has Better Antioxidant and Anti-Inflammatory Properties for Wound Healing?
Natural Ginger Extract Versus Curcumin: Who Has Better Antioxidant and Anti-Inflammatory Properties for Wound Healing? Open
In recent years, foodborne biomaterials have been widely used in wound healing, and they have attracted much attention because of their advantages of green, environmental protection and pollution-free. Therefore ，in this study, ginger, a c…
View article: Clinical Practice Guidelines of Integrated Chinese and Western Medicine Rehabilitation for Spinal Cord Injury
Clinical Practice Guidelines of Integrated Chinese and Western Medicine Rehabilitation for Spinal Cord Injury Open
View article: Learning curve and initial outcomes of a novel percutaneously endoscopic-assisted total hip arthroplasty through mini bikini direct anterior approach: an observational cohort study
Learning curve and initial outcomes of a novel percutaneously endoscopic-assisted total hip arthroplasty through mini bikini direct anterior approach: an observational cohort study Open
Objective Although the direct anterior approach can reduce muscle damage and ensure accurate prosthesis placement, the steep learning curve and increased risk of complications associated with DAA necessitate careful consideration. Therefor…
View article: Comparison of remimazolam tosilate and propofol during induction and maintenance of general anesthesia in patients undergoing laparoscopic cholecystectomy: a prospective, single center, randomized controlled trial
Comparison of remimazolam tosilate and propofol during induction and maintenance of general anesthesia in patients undergoing laparoscopic cholecystectomy: a prospective, single center, randomized controlled trial Open
View article: Identifying Telomere-Related Genes as Prognostic Biomarkers of Cholangiocarcinoma and Exploring Their Biological Functions Based on Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data
Identifying Telomere-Related Genes as Prognostic Biomarkers of Cholangiocarcinoma and Exploring Their Biological Functions Based on Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Open
Objective To investigate the functional and biological significance of telomere-related active genes in cholangiocarcinoma (CCA) using single-cell sequencing and cell communication analysis. Methods First, we identified and annotated diffe…