Explanipedia

The Utility of Novel Renal Biomarkers in Assessment of Chronic Kidney Disease of Unknown Etiology (CKDu): A Review Open

T. D. K. S. C. Gunasekara, P. Mangala C.S. De Silva, Chula Herath, Sisira Siribaddana, Nipuna Siribaddana , et al. · 2020

Chronic Kidney Disease (CKD) is a globally prevalent non-communicable disease with significant mortality and morbidity. It is typically associated with diabetes and hypertension; however, over the last two decades, an emergence of CKD of u…

Chronic interstitial nephritis in agricultural communities is a toxin-induced proximal tubular nephropathy Open

Benjamin A. Vervaet, Cynthia C. Nast, Channa Jayasumana, Gerd Schreurs, Frank Roels , et al. · 2019

Emerging Chronic Kidney Disease of uncertain aetiology (CKDu) among rural farming communities in Southern and Uva Provinces of Sri Lanka Open

G Wanniarachchi, Dr Nimasha Ekanayaka, Sisira Ediriweera, H.B. Asanthi, Sudheera Jayasinghe , et al. · 2019

TPS 723: Low and middle income countries: sanitation infections and other health effects, Exhibition Hall, Ground floor, August 26, 2019, 3:00 PM - 4:30 PM Chronic Kidney Disease of uncertain aetiology (CKDu) is an endemic disease occurrin…

SAT-230 OCCUPATIONAL HERBICIDE EXPOSURE AND DECLINING KIDNEY FUNCTIONS AMONG SUGARCANE FARMERS IN RURAL SRI LANKA. Open

P.M.C. DE SILVA, Khaja Shameem Mohammed Abdul, Sudheera Jayasinghe, S. Devi Chandana, Channa Jayasumana , et al. · 2019

Paraquat and Glyphosate were leading herbicides among Sugarcane Farmers (SF) hence occupational exposure is inevitable. These have been recently linked with the development of Chronic Kidney Disease of unknown aetiology (CKDu). Urinary KIM…

A novel ultrasound technique to detect early chronic kidney disease Open

Dulitha K. Hewadikaram, Mudhitha Bandara, Amal N. Pattivedana, Hiran Jayaweera, K. Jayananda , et al. · 2019

Chronic kidney disease (CKD) of unknown etiology is recognized as a major public health challenge and a leading cause of morbidity and mortality in the dry zone in Sri Lanka. CKD is asymptomatic and are diagnosed only in late stages. Evide…

Comparison of medication adherence between type 2 diabetes mellitus patients who pay for their medications and those who receive it free: a rural Asian experience Open

Devarajan Rathish, Ruvini Hemachandra, Thilini Premadasa, Sasini Ramanayake, Chathuri Rasangika , et al. · 2019

There was no significant difference in medication adherence between the universal-free group and fee-paying group, despite of having a significantly different income. The universal-free health service would be a probable reason.

Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka Open

Devarajan Rathish, Channa Jayasumana, Suneth Agampodi · 2019

Additional file 1: of Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka Open

Devarajan Rathish, Channa Jayasumana, Suneth Agampodi · 2019

DPP4Is and other oral hypoglycemic agents, Anuradhapura, Sri Lankaâ 2017. This contains the data of the entire study. (XLS 189 kb)

Additional file 1: of Comparison of medication adherence between type 2 diabetes mellitus patients who pay for their medications and those who receive it free: a rural Asian experience Open

Devarajan Rathish, Ruvini Hemachandra, Thilini Premadasa, Sasini Ramanayake, Chathuri Rasangika , et al. · 2019

Medication adherence among patients with type 2 diabetes mellitus of Anuradhapura, Sri Lanka, 2017. This provides the results of the entire study with data for each institution. (XLS 153 kb)

Acetylcholinesterase inhibitor insecticides related acute poisoning, availability and sales: trends during the post-insecticide-ban period of Anuradhapura, Sri Lanka Open

Devarajan Rathish, Suneth Agampodi, Channa Jayasumana · 2018

Hospital admissions related to acute poisoning was declining along with the overall sales of remaining AChEIIs, during the post-AChEII ban period. Nevertheless, future vigilance is needed on the remaining AChEIIs to predict and prevent rel…

Red blood cell acetylcholinesterase activity among healthy dwellers of an agrarian region in Sri Lanka: a descriptive cross-sectional study Open

Devarajan Rathish, Indika Senavirathna, Channa Jayasumana, Suneth Agampodi · 2018

Early renal damage among children living in the region of highest burden of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka Open

Suneth Agampodi, Gayani Amarasinghe, P. G. C. R. Naotunna, Channa Jayasumana, Sisira Siribaddana · 2018

A novel ultrasound technique to detect early chronic kidney disease Open

Dulitha K. Hewadikaram, Mudhitha Bandara, Amal N. Pattivedana, Hiran Jayaweera, K. Jayananda , et al. · 2018

Chronic kidney disease (CKD) of unknown etiology is recognized as a major public health challenge and a leading cause of morbidity and mortality in the dry zone in Sri Lanka. CKD is asymptomatic and are diagnosed only in late stages. Evide…

Morphological and clinical findings in Sri Lankan patients with chronic kidney disease of unknown cause (CKDu): Similarities and differences with Mesoamerican Nephropathy Open

Julia Wijkström, Channa Jayasumana, Rajeewa Dassanayake, Nalin Priyawardane, Nimali Godakanda , et al. · 2018

In Sri Lanka, an endemic of chronic kidney disease of unknown origin (CKDu) is affecting rural communities. The endemic has similarities with Mesoamerican Nephropathy (MeN) in Central America, however it has not yet been clarified if the e…

Additional file 1: of Acetylcholinesterase inhibitor insecticides related acute poisoning, availability and sales: trends during the post-insecticide-ban period of Anuradhapura, Sri Lanka Open

Devarajan Rathish, Suneth Agampodi, Channa Jayasumana · 2018

Admissions, availability, and sales related to acute AChEII poisoning, AChEII study, Anuradhapura, 2017. This provides the data of the entire survey and the results of chi-square for goodness of fit. (XLS 50 kb)

Additional file 1: of Red blood cell acetylcholinesterase activity among healthy dwellers of an agrarian region in Sri Lanka: a descriptive cross-sectional study Open

Devarajan Rathish, Indika Senavirathna, Channa Jayasumana, Suneth Agampodi · 2018

RBC AChE activity among healthy non-farmers of Anuradhapura, 2017. It contains the data of the entire study. (XLS 49 kb)

Kidney Diseases in Agricultural Communities: A Case Against Heat-Stress Nephropathy Open

Chula Herath, Channa Jayasumana, P. Mangala C.S. De Silva, P.H. Chaminda De Silva, Sisira Siribaddana , et al. · 2017

Pharmacology education and antibiotic self-medication among medical students: a cross-sectional study Open

Devarajan Rathish, Buddhika Wijerathne, Sandaruwan Bandara, Susanhitha Piumanthi, Chamali Senevirathna , et al. · 2017

Overall, 39% [(110/285) 95% CI 32.9-44.3] of students were found to have antibiotic self-medication. The percentage for antibiotic self-medication progressively increased with the year of study. The percentage of antibiotic self-medication…

Availability of essential medicines in selected public, primary and secondary health care institutions of a rural Sri Lankan district: a spot survey Open

Devarajan Rathish, Indika Premarathna, Thiwanka Jayathilake, Chathurika Kandegedara, Kalani Punchihewa , et al. · 2017

Availability of essential medicines in most of the primary and the secondary care institutions were fairly high. Deficiency in medicines needed for the management of emergencies was noted. A need based annual estimate of medicines based on…

Additional file 1: of Availability of essential medicines in selected public, primary and secondary health care institutions of a rural Sri Lankan district: a spot survey Open

Devarajan Rathish, Indika Premarathna, Thiwanka Jayathilake, Chathurika Kandegedara, Kalani Punchihewa , et al. · 2017

Availability of essential medicines in a rural Sri Lankan district, 2016. This provides the results of the entire survey with data for each essential medicine. (XLS 187Â kb)

Reverse osmosis plant maintenance and efficacy in chronic kidney disease endemic region in Sri Lanka Open

Channa Jayasumana, Omesh N. Ranasinghe, Sachini Ranasinghe, Imalka Siriwardhana, Sarath Gunatilake , et al. · 2016

Chronic interstitial nephritis in agricultural communities: a worldwide epidemic with social, occupational and environmental determinants Open

Channa Jayasumana, Carlos Orantes, Raúl Herrera, Miguel Almaguer, Laura López , et al. · 2016

Increase in the prevalence of chronic kidney disease (CKD) is observed in Central America, Sri Lanka and other tropical countries. It is named chronic interstitial nephritis in agricultural communities (CINAC). CINAC is defined as a form o…

Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka Open

P. Mangala C.S. De Silva, Khaja Shameem Mohammed Abdul, Eakanayake M. D. V. Eakanayake, Sudheera Jayasinghe, Channa Jayasumana , et al. · 2016

Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubuloint…

Drug utilization, prescription errors and potential drug-drug interactions: an experience in rural Sri Lanka Open

Devarajan Rathish, S Bahini, Thanikai Sivakumar, T Thiranagama, T Abarajithan , et al. · 2016

Atorvastatin was the most frequently prescribed substance. Fifteen percent of the prescriptions originate from government sector. SLMC registration number and trade names were seen more in prescriptions originating from the private sector.…

Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka Open

Duleeka Knipe, Channa Jayasumana, Sisira Siribaddana, Chamil Priyadarshana, Melissa Pearson , et al. · 2016

Measuring chronic pesticide exposure is important in order to investigate the associated health effects. Traditional biological samples (blood/urine) are difficult to collect, store and transport in large epidemiological studies in setting…

Assessment of legibility and completeness of prescriptions dispensed at State Pharmaceutical Corporation, Anuradhapura Open

Devarajan Rathish, S Bahini, T Sivakumar, T Thiranagama, T Abarajithan , et al. · 2015

The AMJ is a peer-reviewed, triannual health journal published by Anuradhapura Clinical Society (ACS).The Journal strives to be a forum for all health professionals to publish original research and review articles in their area of expertis…

A study on potential drug – drug interaction among prescriptions dispensed at State Pharmaceutical Corporation, Anuradhapura Open

Devarajan Rathish, S Bahini, T Sivakumar, T Thiranagama, T Abarajithan , et al. · 2015

The AMJ is a peer-reviewed, triannual health journal published by Anuradhapura Clinical Society (ACS).The Journal strives to be a forum for all health professionals to publish original research and review articles in their area of expertis…

Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy Open

Channa Jayasumana, Sarath Gunatilake, Sisira Siribaddana · 2015

Phosphate fertilizer is a main source of arsenic in areas affected with chronic kidney disease of unknown etiology in Sri Lanka Open

Channa Jayasumana, S.I. Fonseka, P. U. Ashvin Iresh Fernando, K. Jayalath, M. D. Amarasinghe , et al. · 2015

Chronic Kidney Disease of unknown etiology (CKDu) has escalated into an epidemic in North Central Province (NCP) and adjacent farming areas in the dry zone of Sri Lanka. Studies have shown that this special type of CKD is a toxic nephropat…

Letter to the Editor Open

Channa Jayasumana, Sisira Siribaddana · 2015

Channa Jayasumana YOU? Author Swipe