Chao Wu
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View article: Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury
Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury Open
The heat‐sensitive transient receptor potential vanilloid 1 (TRPV1), which is highly expressed on cardiac sensory neurons, reportedly plays a crucial role in transmitting nociceptive signals from the heart to the spinal cord during myocard…
View article: SN 2017ckj: A linearly declining type IIb supernova with a relatively massive hydrogen envelope
SN 2017ckj: A linearly declining type IIb supernova with a relatively massive hydrogen envelope Open
We present optical observations of the type IIb supernova (SN) 2017ckj, covering approximately 180 days after the explosion. Its early-time multi-band light curves display no clear evidence of a shock-cooling tail, resembling the behaviour…
View article: Immunodominant T cell responses to SARS-CoV-2 nucleocapsid protein in Omicron breakthrough infection post-inactivated vaccination
Immunodominant T cell responses to SARS-CoV-2 nucleocapsid protein in Omicron breakthrough infection post-inactivated vaccination Open
The widespread administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has not eliminated breakthrough infections due to immune evasion by viral mutations. Whether individuals with breakthrough infections ca…
View article: A Review on the Role of DNA Methylation in Aortic Disease Associated With Marfan Syndrome
A Review on the Role of DNA Methylation in Aortic Disease Associated With Marfan Syndrome Open
Marfan syndrome (MFS) is a genetic disorder primarily affecting the connective tissue, with cardiovascular complications as the leading cause of mortality. While mutations in the FBN1 gene are the primary cause, the severity and progressio…
View article: <scp>HIF</scp>‐1α‐Induced <scp>GPR171</scp> Expression Mediates <scp>CCL2</scp> Secretion by Mast Cells to Promote Gastric Inflammation During <i>Helicobacter pylori</i> Infection
<span>HIF</span>‐1α‐Induced <span>GPR171</span> Expression Mediates <span>CCL2</span> Secretion by Mast Cells to Promote Gastric Inflammation During <i>Helicobacter pylori</i> Infection Open
Background Helicobacter pylori ( H. pylori ) infection is one of the most important risk factors for chronic gastritis, gastric ulcers, and gastric cancer. Mast cells act as a crucial regulator in bacterial infection. The mechanisms underl…
View article: The relationship between the composite dietary antioxidant index and rheumatoid arthritis risk in American adults: the mediating role of BMI
The relationship between the composite dietary antioxidant index and rheumatoid arthritis risk in American adults: the mediating role of BMI Open
Background The Clinical Dietary Antioxidant Index (CDAI) is a dietary antioxidant assessment index. Although CDAI has been shown to play a role in various chronic diseases, its association with rheumatoid arthritis (RA) remains underexplor…
View article: Association between body roundness index and osteoarthritis/rheumatoid arthritis: a cross-sectional study
Association between body roundness index and osteoarthritis/rheumatoid arthritis: a cross-sectional study Open
To explore the relationship between the Body Roundness Index (BRI) and the prevalence of osteoarthritis (OA) and rheumatoid arthritis (RA) among American adults, providing new insights for identifying OA and RA in adults. We analyzed data …
View article: Gastric mucosal CD8+TRM cells are recruited through CXCR5-CXCL13 axis in Helicobacter pylori infected subjects
Gastric mucosal CD8+TRM cells are recruited through CXCR5-CXCL13 axis in Helicobacter pylori infected subjects Open
Gastric mucosal CD8+ tissue-resident memory T (CD8+TRM) cells are increased in Helicobacter pylori (H. pylori) infected subjects, but the characteristics and chemotactic mechanism of CD8+TRM…
View article: Rewrite to Jailbreak: Discover Learnable and Transferable Implicit Harmfulness Instruction
Rewrite to Jailbreak: Discover Learnable and Transferable Implicit Harmfulness Instruction Open
As Large Language Models (LLMs) are widely applied in various domains, the safety of LLMs is increasingly attracting attention to avoid their powerful capabilities being misused. Existing jailbreak methods create a forced instruction-follo…
View article: Association between serum high-sensitivity C-reactive protein levels and osteoarthritis in adults from NHANES 2015 to 2018
Association between serum high-sensitivity C-reactive protein levels and osteoarthritis in adults from NHANES 2015 to 2018 Open
To explore the association between serum high-sensitivity C-reactive protein (HSCRP) levels and osteoarthritis (OA) in adults, providing new evidence for the diagnosis of adult OA. We selected data from the 2015-2018 National Health and Nu…
View article: Multitranscriptome analysis reveals stromal cells in the papillary dermis to promote angiogenesis in psoriasis vulgaris
Multitranscriptome analysis reveals stromal cells in the papillary dermis to promote angiogenesis in psoriasis vulgaris Open
Background The pathogenesis of psoriasis is incompletely understood. Growing evidence suggests the involvement of stromal cells in the inflammatory process. Objectives To investigate the roles of stromal cells, including fibroblasts, vascu…
View article: Simultaneous Multiband Photometry of the Early Optical Afterglow of GRB 240825A with Mephisto
Simultaneous Multiband Photometry of the Early Optical Afterglow of GRB 240825A with Mephisto Open
Gamma-ray bursts (GRBs) are the most luminous transients in the universe. The interaction of the relativistic jet with the circumburst medium produces an afterglow and generates multiwavelength emission. In this work, we present simultaneo…
View article: Spatial proteomic profiling elucidates immune determinants of neoadjuvant chemo-immunotherapy in esophageal squamous cell carcinoma
Spatial proteomic profiling elucidates immune determinants of neoadjuvant chemo-immunotherapy in esophageal squamous cell carcinoma Open
Esophageal squamous cell carcinoma (ESCC) presents significant clinical and therapeutic challenges due to its aggressive nature and generally poor prognosis. We initiated a Phase II clinical trial (ChiCTR1900027160) to assess the efficacy …
View article: Helicobacter pylori upregulates PAD4 expression via stabilising HIF-1α to exacerbate rheumatoid arthritis
Helicobacter pylori upregulates PAD4 expression via stabilising HIF-1α to exacerbate rheumatoid arthritis Open
View article: Risk assessment and prediction of nosocomial infections based on surveillance data using machine learning methods
Risk assessment and prediction of nosocomial infections based on surveillance data using machine learning methods Open
View article: Characteristics of Norovirus capsid protein-specific CD8 <sup>+</sup> T-Cell responses in previously infected individuals
Characteristics of Norovirus capsid protein-specific CD8 <sup>+</sup> T-Cell responses in previously infected individuals Open
Norovirus (NV) infection causes acute gastroenteritis in children and adults. Upon infection with NV, specific CD8+ T cells, which play an important role in anti-infective immunity, are activated in the host. Owing to the NV's w…
View article: A new species of Elimaea (Poaefoliana) Ingrisch (Orthoptera: Tettigoniidae: Phaneropterinae) from China
A new species of Elimaea (Poaefoliana) Ingrisch (Orthoptera: Tettigoniidae: Phaneropterinae) from China Open
This dataset contains the digitized treatments in Plazi based on the original journal article Wu, Chao, Liao, Xin-Yi, Liu, Chun-Xiang (2024): A new species of Elimaea (Poaefoliana) Ingrisch (Orthoptera: Tettigoniidae: Phaneropterinae) from…
View article: P2.31-10 Clinical Outcomes of Real-World Treatment for Metastatic EGFRm NSCLC after Osimertinib and Platinum-Based Chemotherapy
P2.31-10 Clinical Outcomes of Real-World Treatment for Metastatic EGFRm NSCLC after Osimertinib and Platinum-Based Chemotherapy Open
View article: <i>Helicobacter pylori</i> induces urease subunit B‐specific CD8<sup>+</sup> T cell responses in infected individuals via cytosolic pathway of cross‐presentation
<i>Helicobacter pylori</i> induces urease subunit B‐specific CD8<sup>+</sup> T cell responses in infected individuals via cytosolic pathway of cross‐presentation Open
Background Urease subunit B (UreB), a conserved and key virulence factor of Helicobacter pylori ( H. pylori ), can induce the host CD4 + T cell immune responses to provide protection, but less is known regarding CD8 + T cell responses. The…
View article: Cd8+ Trm Cells Were Recruited to Gastric Mucosa Through Cxcl11/Cxcr3 Against H. Pylori Colonization in Mice
Cd8+ Trm Cells Were Recruited to Gastric Mucosa Through Cxcl11/Cxcr3 Against H. Pylori Colonization in Mice Open
View article: ZEB1 promotes DNA homologous recombination repair and contributes to the 5-Fluorouracil resistance in colorectal cancer.
ZEB1 promotes DNA homologous recombination repair and contributes to the 5-Fluorouracil resistance in colorectal cancer. Open
Chemotherapy resistance represents a significant obstacle in clinical practice of colorectal cancer (CRC). In this study we aim to clarify the underlying mechanism of chemotherapy resistance mediated by ZEB1 in CRC. shRNA-mediated repressi…
View article: A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents Open
Pain signals are relayed to the brain via a nociceptive system, and in rare cases, this nociceptive system contains genetic variants that can limit the pain response. Here, we questioned whether a human transient receptor potential vanillo…
View article: CXCL8, CXCL9, CXCL10, and CXCL11 as biomarkers of liver injury caused by chronic hepatitis B
CXCL8, CXCL9, CXCL10, and CXCL11 as biomarkers of liver injury caused by chronic hepatitis B Open
Background Chronic hepatitis B (CHB) remains a significant global health problem, leading to recurrent inflammation and liver-damaging diseases such as fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Currently, although diagnostic…
View article: Spinal cord astrocytes regulate myocardial ischemia–reperfusion injury
Spinal cord astrocytes regulate myocardial ischemia–reperfusion injury Open
View article: Development and validation of an efficient nomogram for risk assessment of norovirus infection in pediatric patients
Development and validation of an efficient nomogram for risk assessment of norovirus infection in pediatric patients Open
View article: AB0076 DOES HELICOBACTER PYLORI HAVE AN IMPACT ON RHEUMATOID ARTHRITIS?
AB0076 DOES HELICOBACTER PYLORI HAVE AN IMPACT ON RHEUMATOID ARTHRITIS? Open
View article: Epidemiology and prediction of multidrug-resistant bacteria based on hospital level
Epidemiology and prediction of multidrug-resistant bacteria based on hospital level Open
View article: Cytotoxin-Associated Gene A-Negative Helicobacter pylori Promotes Gastric Mucosal CX3CR1+CD4+ Effector Memory T Cell Recruitment in Mice
Cytotoxin-Associated Gene A-Negative Helicobacter pylori Promotes Gastric Mucosal CX3CR1+CD4+ Effector Memory T Cell Recruitment in Mice Open
Background Helicobacter pylori can cause many kinds of gastric disorders, ranging from gastritis to gastric cancer. Cytotoxin-associated gene A (CagA) + H. pylori is more likely to cause gastric histopathologic damage than CagA – H. pylori…
View article: HBeAg Negativity is Associated with a Higher Risk of Liver-Related Death in Patients with Chronic Hepatitis B Related Liver Cirrhosis
HBeAg Negativity is Associated with a Higher Risk of Liver-Related Death in Patients with Chronic Hepatitis B Related Liver Cirrhosis Open
Background and aims Few studies reported the association between the survival of patients with chronic hepatitis B (CHB)-related liver cirrhosis (LC) and hepatitis B e antigen (HBeAg) state. Methods Three hundred and ninety-eight CHB-LC pa…
View article: HBeAg Negativity is Associated with a Higher Risk of Liver-Related Death in Patients with Chronic Hepatitis B Related Liver Cirrhosis
HBeAg Negativity is Associated with a Higher Risk of Liver-Related Death in Patients with Chronic Hepatitis B Related Liver Cirrhosis Open
Background and aims Few studies reported the association between the survival of patients with chronic hepatitis B (CHB)-related liver cirrhosis (LC) and hepatitis B e antigen (HBeAg) state. Methods<…