Chaobin Qin
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View article: A Characterization and Functional Analysis of Peroxisome Proliferator-Activated Receptor Gamma Splicing Variants in the Buffalo Mammary Gland
A Characterization and Functional Analysis of Peroxisome Proliferator-Activated Receptor Gamma Splicing Variants in the Buffalo Mammary Gland Open
Peroxisome proliferator-activated receptor γ (PPARG) has various splicing variants and plays essential roles in the regulation of adipocyte differentiation and lipogenesis. However, little is known about the expression pattern and effect o…
View article: Taurine Alleviated the Negative Effects of an Oxidized Lipid Diet on Growth Performance, Antioxidant Properties, and Muscle Quality of the Common Carp (<i>Cyprinus carpio</i> L.)
Taurine Alleviated the Negative Effects of an Oxidized Lipid Diet on Growth Performance, Antioxidant Properties, and Muscle Quality of the Common Carp (<i>Cyprinus carpio</i> L.) Open
In the present study, we conducted a 10‐week culture experiment to investigate the effects of taurine on the growth performance, antioxidant properties, and muscle quality of the common carp fed an oxidized lipid diet. There were five expe…
View article: The Effect of High Levels Carbohydrate on Intestinal Microbiota, Metabolites, and Health of Common Carp (<i>Cyprinus carpio</i> L.)
The Effect of High Levels Carbohydrate on Intestinal Microbiota, Metabolites, and Health of Common Carp (<i>Cyprinus carpio</i> L.) Open
Long‐term consumption of high‐carbohydrate feed may adversely affect intestinal health of fish; however, the underlying roles remain ambiguous. This study examined the effects of varying carbohydrate levels on the intestinal flora of commo…
View article: (‐)‐Epigallocatechin‐3‐O‐Gallate Regulates Muscle Growth, Antioxidant Status, and Nutritional Composition of Juvenile Common Carp (<i>Cyprinus carpio</i> L.)
(‐)‐Epigallocatechin‐3‐O‐Gallate Regulates Muscle Growth, Antioxidant Status, and Nutritional Composition of Juvenile Common Carp (<i>Cyprinus carpio</i> L.) Open
Among the polyphenolic compounds commonly found in green tea, (‐)‐epigallocatechin‐3‐gallate (EGCG) is known to have various functions, including the promotion of antioxidant and myofiber growth in mammals. However, the effect of EGCG on c…
View article: Dietary Bile Acid Supplementation Could Regulate the Glucose, Lipid Metabolism, and Microbiota of Common Carp (Cyprinus carpio L.) Fed with a High-Lipid Diet
Dietary Bile Acid Supplementation Could Regulate the Glucose, Lipid Metabolism, and Microbiota of Common Carp (Cyprinus carpio L.) Fed with a High-Lipid Diet Open
This study sought to examine the role of bile acids in the regulation of glucose and lipid metabolism, intestinal flora, and growth in high-fat diet-fed common carp (Cyprinus carpio L.). Fish ( 6.34 ± 0.07 g ) were fed for 56 days with…
View article: Effects of Genistein on Lipid Metabolism, Antioxidant Activity, and Immunity of Common Carp (Cyprinus carpio L.) Fed with High-Carbohydrate and High-Fat Diets
Effects of Genistein on Lipid Metabolism, Antioxidant Activity, and Immunity of Common Carp (Cyprinus carpio L.) Fed with High-Carbohydrate and High-Fat Diets Open
A 56-day feeding trial was conducted to investigate the effects of genistein on growth, lipid metabolism, antioxidant capacity, and immunity of common carp fed with high-carbohydrate or high-fat diets. Five diets were used to feed fish: co…
View article: Adiponectin and adiponectin receptors in common carp (Cyprinus carpio): Tissue distribution and their expressions in response to high-carbohydrate and high-lipid diets
Adiponectin and adiponectin receptors in common carp (Cyprinus carpio): Tissue distribution and their expressions in response to high-carbohydrate and high-lipid diets Open
In order to investigate the roles of adiponectin in glucose and lipid metabolism in common carp, the tissue distribution of adiponectin and its receptor genes in common carp were firstly detected in this study, and then the effects of high…
View article: Irisin Regulates Hepatic Glucose Metabolism via AMPK and PI3K/Akt Activation
Irisin Regulates Hepatic Glucose Metabolism via AMPK and PI3K/Akt Activation Open
Irisin plays a crucial role in the glucose metabolism of mammals and fish. However, the mechanism by which irisin regulates hepatic glucose metabolism is not entirely known. To clarify irisin’s function and underlying mechanisms in common …
View article: Evaluating the mixture of earthworm meal and wormcast as a protein source for common carp (Cyprinus carpio L.) based on growth performance, antioxidant, immune capacity, lipid metabolism and intestinal health
Evaluating the mixture of earthworm meal and wormcast as a protein source for common carp (Cyprinus carpio L.) based on growth performance, antioxidant, immune capacity, lipid metabolism and intestinal health Open
This study was conducted to evaluate the effects of a dietary earthworm meal mixture (earthworm meal: EM and wormcast: WC) for replacing fish meal (FM) on growth performance, antioxidant capacity, lipid metabolism, and intestinal health of…
View article: Effects of Adiponectin on Glucose Metabolism in the Hepatopancreas of Grass Carp (Ctenopharyngodon idella)
Effects of Adiponectin on Glucose Metabolism in the Hepatopancreas of Grass Carp (Ctenopharyngodon idella) Open
Adiponectin plays critical roles in the regulation of energy metabolism in mammals. However, its roles in fish remain to be evaluated. In this study, we examined the tissue distribution characteristics of two adiponectin genes, namely, adi…
View article: Effects of Dietary Bitter Melon Extract on Growth Performance, Antioxidant Capacity, Inflammatory Cytokines Expression, and Intestinal Microbiota in Common Carp (Cyprinus carpio L.)
Effects of Dietary Bitter Melon Extract on Growth Performance, Antioxidant Capacity, Inflammatory Cytokines Expression, and Intestinal Microbiota in Common Carp (Cyprinus carpio L.) Open
Bitter melon extract (BME), which contains a variety of natural bioactive substances, has diversified biological functions. The present study is aimed at evaluating the effects of dietary supplementation of BME on growth performance, antio…
View article: Effects of genistein on glucose and lipid metabolism of common carp (Cyprinus carpio. L) in vivo and in vitro
Effects of genistein on glucose and lipid metabolism of common carp (Cyprinus carpio. L) in vivo and in vitro Open
Genistein exhibits anti-diabetic and anti-lipogenic effects in mammals, however, there are rare reports on the effects of genistein on glucose and lipid metabolism in fish. This study explored the regulation role of genistein on glucose an…
View article: The Regulatory Role of Apelin on the Appetite and Growth of Common Carp (Cyprinus Carpio L.)
The Regulatory Role of Apelin on the Appetite and Growth of Common Carp (Cyprinus Carpio L.) Open
Apelin, a kind of active polypeptide, has many biological functions, such as promoting food intake, enhancing immunity, and regulating energy balance. In mammals, studies have indicated that apelin is involved in regulating food intake. Ho…
View article: Common carp (Cyprinus carpio) orexin: Molecular identification, tissue expression, and the role of Orexin-A in glucose metabolism
Common carp (Cyprinus carpio) orexin: Molecular identification, tissue expression, and the role of Orexin-A in glucose metabolism Open
Orexins are neuropeptides involved in energy homeostasis. In fish, the function of orexin-A in glucose metabolism is less reported. The present study aims to identify the potential role of orexin-A in the glucose absorption and metabolism …
View article: Defatted black soldier fly (Hermetia illucens) larvae meal can replace soybean meal in juvenile grass carp (Ctenopharyngodon idellus) diets
Defatted black soldier fly (Hermetia illucens) larvae meal can replace soybean meal in juvenile grass carp (Ctenopharyngodon idellus) diets Open
In order to study the effects of replacement of soybean meal (SM) with defatted black soldier fly larvae meal (BSFLM) in grass carp production practice, juvenile grass carps with initial body weight of (10.10 ± 0.28) g were selected for su…
View article: Hepatic glucagon receptors expression in response to glucose, insulin, glucagon and immune challenge in grass carp (Ctenophcuyngodon idellus)
Hepatic glucagon receptors expression in response to glucose, insulin, glucagon and immune challenge in grass carp (Ctenophcuyngodon idellus) Open
Since discovery, glucagon biology has remained enigmatic. Studies have shown that glucagon may have physiological effects beyond glucose regulation by binding to its receptor (Gcgr). The potential roles of glucagon and its receptor in the …
View article: The function of miR-122 in the lipid metabolism and immunity of grass carp (Ctenopharyngodon idellus)
The function of miR-122 in the lipid metabolism and immunity of grass carp (Ctenopharyngodon idellus) Open
Abnormal lipid metabolism in the liver due to excessive fat accumulation is a widespread problem in fish. MicroRNA-122 (miR-122), a liver-specific miRNA in vertebrates, is involved in lipid metabolism. In this study, miR-122 was cloned, an…
View article: The Effects of Oral Rehmannia glutinosa Polysaccharide Administration on Immune Responses, Antioxidant Activity and Resistance Against Aeromonas hydrophila in the Common Carp, Cyprinus carpio L
The Effects of Oral Rehmannia glutinosa Polysaccharide Administration on Immune Responses, Antioxidant Activity and Resistance Against Aeromonas hydrophila in the Common Carp, Cyprinus carpio L Open
The effects of the oral administration of Rehmannia glutinosa polysaccharide (RGP-1) on the immunoregulatory properties, antioxidant activity, and resistance against Aeromonas hydrophila in Cyprinus carpio L. were investigated. The purifie…
View article: Additional file 5 of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 5 of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S4. Human T2D-related gene database and their corresponding orthologues in mouse, chicken, frog and zebrafish. To integrate existing knowledge about T2D, 2620 human T2D genes were identified in our database. Correspondingly, 2395, 18…
View article: Additional file 4: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 4: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S3. OMIM disease annotations of human carbohydrate/glucose metabolic genes by DAVID. Some genes are involved in noninsulin-dependent diabetes mellitus, thyroid carcinoma, paraganglioma and gastric stromal sarcoma, glycine encephalopa…
View article: Additional file 8: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 8: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S7. Organism-specific genes by Ensemble Compara. Each gene was manually verified and annotated by HomoloGene, TreeFam, OrthoDB, ZFIN, MGI, Xenbase, and HCOP (Methods). (XLS 71Â kb)
View article: Additional file 3: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 3: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S2. KEGG pathway annotations of zebrafish carbohydrate/glucose metabolic genes by DAVID. We found 791 carbohydrate/glucose metabolic genes in zebrafish that were not only involved in distinct carbohydrate metabolic processes but also…
View article: Additional file 7: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 7: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S6. Five species orthologues. Information including orthologue gene ID, gene name, % identity target species, identical genes to the query gene, orthology confidence and homology type are listed in the table. (XLSX 4387Â kb)
View article: Additional file 6: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals
Additional file 6: of A comparative genomics study of carbohydrate/glucose metabolic genes: from fish to mammals Open
Table S5. The list of overlapping genes between carbohydrate/glucose metabolic genes and type 2 diabetes-associated genes. Respectively, 400, 388, 313, 336 and 464 human, mouse, chicken, frog and zebrafish carbohydrate/glucose metabolic ge…