Chaojie Yang
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View article: Polygenic risk score for type 2 diabetes shows context-dependent effects across populations
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations Open
View article: Regulatory role of ISEcp1 and spacer sequences in blaCTX-M–mediated cephalosporin resistance in Shigella
Regulatory role of ISEcp1 and spacer sequences in blaCTX-M–mediated cephalosporin resistance in Shigella Open
View article: Complete cox 1 gene and ITS sequence of Hirudinaria manillensis and molecular evolution analysis
Complete cox 1 gene and ITS sequence of Hirudinaria manillensis and molecular evolution analysis Open
Background Hirudinaria manillensis is an important blood-sucking medicinal leech widely distributed in Southeast Asia and southern China. It has been shown to treat cardiovascular and cerebrovascular diseases. Molecular identification tech…
View article: Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages
Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages Open
View article: Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations
Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations Open
Polygenic risk scores (PRS) hold prognostic value for identifying individuals at higher risk of type 2 diabetes (T2D). However, further characterization is needed to understand the generalizability of T2D PRS in diverse populations across …
View article: Soluble Immune Checkpoint Protein and Lipid Network Associations with All-Cause Mortality Risk: Trans-Omics for Precision Medicine (TOPMed) Program
Soluble Immune Checkpoint Protein and Lipid Network Associations with All-Cause Mortality Risk: Trans-Omics for Precision Medicine (TOPMed) Program Open
Adverse cardiovascular events are emerging with the use of immune checkpoint therapies in oncology. Using datasets in the Trans-Omics for Precision Medicine program (Multi-Ethnic Study of Atherosclerosis, Jackson Heart Study [JHS], and Fra…
View article: Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages
Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages Open
The brine shrimp Artemia, a crustacean adapted to the extreme conditions of hypersaline environments, comprises nine regionally distributed sexual species scattered (island-like) over heterogeneous environments and asexual (parthenogenetic…
View article: HelloMeme: Integrating Spatial Knitting Attentions to Embed High-Level and Fidelity-Rich Conditions in Diffusion Models
HelloMeme: Integrating Spatial Knitting Attentions to Embed High-Level and Fidelity-Rich Conditions in Diffusion Models Open
We propose an effective method for inserting adapters into text-to-image foundation models, which enables the execution of complex downstream tasks while preserving the generalization ability of the base model. The core idea of this method…
View article: Genomic analysis of an acute gastroenteritis outbreak caused by rotavirus C in Hebei, China
Genomic analysis of an acute gastroenteritis outbreak caused by rotavirus C in Hebei, China Open
View article: The Complex FtBBX22 and FtHY5 Positively Regulates Light-Induced Anthocyanin Accumulation by Activating FtMYB42 in Tartary Buckwheat Sprouts
The Complex FtBBX22 and FtHY5 Positively Regulates Light-Induced Anthocyanin Accumulation by Activating FtMYB42 in Tartary Buckwheat Sprouts Open
Anthocyanin is one important nutrition composition in Tartary buckwheat (Fagopyrum tataricum) sprouts, a component missing in its seeds. Although anthocyanin biosynthesis requires light, the mechanism of light-induced anthocyanin accumulat…
View article: WITHDRAWN: Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages
WITHDRAWN: Mitogenomic phylogeny and divergence time estimation of Artemia Leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages Open
Withdrawal statement The authors have withdrawn this manuscript because the new version of this article has been developed based on the phylogenetic concept of “long branch length and long branch attraction (LBA)”and the validity of “relax…
View article: Characterization of a Salmonella enterica serovar Typhimurium lineage with rough colony morphology and multidrug resistance
Characterization of a Salmonella enterica serovar Typhimurium lineage with rough colony morphology and multidrug resistance Open
View article: Genomic and Phenotypic Analysis of blaKPC-2 Associated Carbapenem Resistance in Klebsiella aerogenes: Insights into Clonal Spread and Resistance Mechanisms Across Hospital Departments in Beijing
Genomic and Phenotypic Analysis of blaKPC-2 Associated Carbapenem Resistance in Klebsiella aerogenes: Insights into Clonal Spread and Resistance Mechanisms Across Hospital Departments in Beijing Open
PURPOSE: This study conducted an phenotypic and whole-genome sequencing analysis with Klebsiella aerogenes to elucidate its clinical epidemiological characteristics, antimicrobial resistance (AMR) phenotype, biofilm formation ability and h…
View article: Indirubin-3′-monoxime exhibits potent antiviral and anti-inflammatory effects against human adenoviruses in vitro and in vivo
Indirubin-3′-monoxime exhibits potent antiviral and anti-inflammatory effects against human adenoviruses in vitro and in vivo Open
Human adenovirus (HAdV) infection is a major cause of respiratory disease, yet no antiviral drugs have been approved for its treatment. Herein, we evaluated the antiviral and anti-inflammatory effects of cyclin-dependent protein kinase (CD…
View article: Investigation of Quantitative Microbial Succession and Dynamic Variations of Physicochemical Properties During the Fermentation Process of Dandouchi (Sojae Semen Praeparatum)
Investigation of Quantitative Microbial Succession and Dynamic Variations of Physicochemical Properties During the Fermentation Process of Dandouchi (Sojae Semen Praeparatum) Open
View article: Tartary Buckwheat (Fagopyrum tataricum) FtTT8 Inhibits Anthocyanin Biosynthesis and Promotes Proanthocyanidin Biosynthesis
Tartary Buckwheat (Fagopyrum tataricum) FtTT8 Inhibits Anthocyanin Biosynthesis and Promotes Proanthocyanidin Biosynthesis Open
Tartary buckwheat (Fagopyrum tataricum) is an important plant, utilized for both medicine and food. It has become a current research hotspot due to its rich content of flavonoids, which are beneficial for human health. Anthocyanins (ATs) a…
View article: Supplementary Data for Chaojie Yang's Dissertation
Supplementary Data for Chaojie Yang's Dissertation Open
Supplementary Data for Chaojie Yang's Dissertation
View article: Supplementary Data for Chaojie Yang's Dissertation
Supplementary Data for Chaojie Yang's Dissertation Open
Supplementary Data for Chaojie Yang's Dissertation
View article: Genetic characterization of a Salmonella enterica serovar Typhimurium isolated from an infant with concurrent resistance to ceftriaxone, ciprofloxacin and azithromycin
Genetic characterization of a Salmonella enterica serovar Typhimurium isolated from an infant with concurrent resistance to ceftriaxone, ciprofloxacin and azithromycin Open
Our findings highlight that continuously monitor the changes in antibiotic resistance patterns and research on the resistance mechanisms in potential human pathogens are imperative.
View article: Resistance in Enteric Shigella and nontyphoidal Salmonella: emerging concepts
Resistance in Enteric Shigella and nontyphoidal Salmonella: emerging concepts Open
Purpose of review The emergence of globally resistant enteric Shigella and nontyphoidal Salmonella strains (NTS) has limited the selection of effective drugs, which has become a major challenge for the treatment of infections. The purpose …
View article: Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts
Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts Open
Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) play critical roles in human health. Prior genome-wide association studies (GWAS) of n-3 and n-6 PUFAs in European Americans from the CHARGE Consortium have documented str…
View article: Genome-Wide Identification of R2R3-MYB Transcription Factor Family in Tartary Buckwheat (Fagopyrum tataricum) Identifies a Member Involved in Anthocyanin Biosynthesis
Genome-Wide Identification of R2R3-MYB Transcription Factor Family in Tartary Buckwheat (Fagopyrum tataricum) Identifies a Member Involved in Anthocyanin Biosynthesis Open
Tartary buckwheat (Fagopyrum tataricum Gaertn.) belongs to the family of Polygonaceae and is used as a multi-functional plant. R2R3-MYB transcription factors play a crucial part in plant growth and are involved in many biological processes…
View article: A novel humanized tri‐receptor transgenic mouse model of HAdV infection and pathogenesis
A novel humanized tri‐receptor transgenic mouse model of HAdV infection and pathogenesis Open
Human adenovirus (HAdV) is a highly virulent respiratory pathogen that poses clinical challenges in terms of diagnostics and treatment. Currently, no effective therapeutic drugs or prophylactic vaccines are available for HAdV infections. O…
View article: Association of rs35006907 Polymorphism with Risk of Dilated Cardiomyopathy in Han Chinese Population
Association of rs35006907 Polymorphism with Risk of Dilated Cardiomyopathy in Han Chinese Population Open
Background Several investigations have demonstrated the association of MTSS1 with left ventricular (LV) structure and function. A recently published study has even revealed that rs35006907 was associated with both MTSS1 expression and the …
View article: Dietary Sources of Linoleic Acid (LA) Differ by Race/Ethnicity in Adults Participating in the National Health and Nutrition Examination Survey (NHANES) between 2017–2018
Dietary Sources of Linoleic Acid (LA) Differ by Race/Ethnicity in Adults Participating in the National Health and Nutrition Examination Survey (NHANES) between 2017–2018 Open
Linoleic acid (LA) is a primary n-6 polyunsaturated fatty acid (PUFA), which is of interest to nutritional professionals as it has been associated with health outcomes. However, as some LA-rich foods offer protection against chronic diseas…
View article: FHL5 Controls Vascular Disease–Associated Gene Programs in Smooth Muscle Cells
FHL5 Controls Vascular Disease–Associated Gene Programs in Smooth Muscle Cells Open
Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic insights for …
View article: Successful clearance of persistent SARS-CoV-2 asymptomatic infection following a single dose of Ad5-nCoV vaccine
Successful clearance of persistent SARS-CoV-2 asymptomatic infection following a single dose of Ad5-nCoV vaccine Open
View article: The complete mitochondrial genome of Indo-Pacific soft coral <i>Sinularia acuta</i> Manuputty and van Ofwegen, 2007 (Octocorallia: Alcyonacea)
The complete mitochondrial genome of Indo-Pacific soft coral <i>Sinularia acuta</i> Manuputty and van Ofwegen, 2007 (Octocorallia: Alcyonacea) Open
The complete mitochondrial genome (mitogenome) of the soft coral Sinularia acuta Manuputty and van Ofwegen, 2007 was sequenced and annotated using Illumina next-generation sequencing (NGS). The mitogenome of S. acuta was 18,7…
View article: Genome-Wide Association Studies and fine-mapping of genomic loci for n-3 and n-6 Polyunsaturated Fatty Acids in Hispanic American and African American Cohorts
Genome-Wide Association Studies and fine-mapping of genomic loci for n-3 and n-6 Polyunsaturated Fatty Acids in Hispanic American and African American Cohorts Open
View article: Supplementary Material for: <i>Mycobacterium avium</i> Complex Infections: Detailed Phenotypic and Functional Immunological Work-Up Is Required despite Genetic Analyses
Supplementary Material for: <i>Mycobacterium avium</i> Complex Infections: Detailed Phenotypic and Functional Immunological Work-Up Is Required despite Genetic Analyses Open
Introduction: Cervical scrofulous lymphadenitis due to Mycobacterium avium complex (MAC) in immunocompetent adults is a rare disease. The presence of MAC infections demands meticulous clinical evaluation of patients al…