Chaoqun Gu
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View article: Salivary microbiome in patients with benign prostatic hyperplasia: altered composition and its association with prostate-specific antigen
Salivary microbiome in patients with benign prostatic hyperplasia: altered composition and its association with prostate-specific antigen Open
Backgrounds Microbial dysbiosis in the gut and urine has been implicated in patients with benign prostatic hyperplasia (BPH) in previous studies. Additionally, emerging evidence suggests that salivary dysbiosis is associated with various d…
View article: Advances in nutritional risk screening tools for hospitalized patients with type 2 diabetes mellitus
Advances in nutritional risk screening tools for hospitalized patients with type 2 diabetes mellitus Open
Object: With the intensification of the global aging population trend and changes in lifestyle, the prevalence of type 2 diabetes mellitus (T2DM) continues to rise, and it has become a major global public health problem. Malnutrition is an…
View article: Antibiotics for UTIs Cause Distinct Alterations in Gut Microbiome and Host Health Compared to Enteritis Treatment
Antibiotics for UTIs Cause Distinct Alterations in Gut Microbiome and Host Health Compared to Enteritis Treatment Open
Background Fecal microbiota transplantation (FMT) has gained attention as a potential treatment for various chronic inflammatory diseases, including colitis and urinary tract infections (UTIs). However, the effects of different antibiotics…
View article: Impact of Prolonged Antibiotic Treatment on Gut and Kidney Microbiota: Insights from a Rat Model
Impact of Prolonged Antibiotic Treatment on Gut and Kidney Microbiota: Insights from a Rat Model Open
Background Maintaining a harmonious microbiota is fundamental for overall well-being. This study aims to investigate the consequences of one- and two-week antibiotic treatments on gut and kidney microbiota using a rat model and assess stru…
View article: Sex-Specific Dysbiotic Bladder Microbiome in CKD Uncovered via High-Throughput Sequencing and Culture
Sex-Specific Dysbiotic Bladder Microbiome in CKD Uncovered via High-Throughput Sequencing and Culture Open
Background High-throughput techniques confirm the human bladder microbiome, but its relation to chronic kidney disease (CKD) remains unexplored. Bladder bacteria may migrate to the kidneys, affecting CKD. Methods A cross-sectional study re…
View article: Salivary Microbiome in Patients with Benign Prostatic Hyperplasia: Altered Composition and Association with Prostate-Specific Antigen
Salivary Microbiome in Patients with Benign Prostatic Hyperplasia: Altered Composition and Association with Prostate-Specific Antigen Open
Backgrounds Microbial dysbiosis in the gut and urine has been implicated in patients with benign prostatic hyperplasia (BPH) based on previous studies. Additionally, emerging evidence has shown that salivary dysbiosis is associated with va…
View article: The bladder microbiome of chronic kidney disease with associations to demographics, renal function, and serum cytokines
The bladder microbiome of chronic kidney disease with associations to demographics, renal function, and serum cytokines Open
Background High throughput 16S rRNA gene sequencing and enhanced culture methods (e.g., expanded quantitative urine culture, EQUC) have established the existence of the human bladder microbiome. We aim to test the hypothesis that the bladd…
View article: Salivary microbiome in chronic kidney disease: what is its connection to diabetes, hypertension, and immunity?
Salivary microbiome in chronic kidney disease: what is its connection to diabetes, hypertension, and immunity? Open
View article: The Bladder Microbiome, Metabolome, Cytokines, and Phenotypes in Patients with Systemic Lupus Erythematosus
The Bladder Microbiome, Metabolome, Cytokines, and Phenotypes in Patients with Systemic Lupus Erythematosus Open
Contrary to dogma, the human urinary bladder possesses its own unique bacterial community with alteration of composition associated with disease states. Systemic lupus erythematosus (SLE) is a complex autoimmune disease often characterized…
View article: Alteration of Skin Microbiome in CKD Patients Is Associated With Pruritus and Renal Function
Alteration of Skin Microbiome in CKD Patients Is Associated With Pruritus and Renal Function Open
Dysbiotic gut microbiome in chronic kidney disease (CKD) patients has been extensively explored in recent years. Skin microbiome plays a crucial role in patients with skin diseases or even systemic disorders. Pruritus is caused by the rete…
View article: Gut Mycobiome in Patients With Chronic Kidney Disease Was Altered and Associated With Immunological Profiles
Gut Mycobiome in Patients With Chronic Kidney Disease Was Altered and Associated With Immunological Profiles Open
Objectives Mounting evidence suggests that bacterial dysbiosis and immunity disorder are associated with patients with chronic kidney disease (CKD), but the mycobiome is beginning to gain recognition as a fundamental part of our microbiome…
View article: The bladder microbiome, metabolome, cytokines, and phenotypes in patients with systemic lupus erythematosus
The bladder microbiome, metabolome, cytokines, and phenotypes in patients with systemic lupus erythematosus Open
Background and aims Emerging studies reveal a unique bacterial community in the human bladder, with alteration of composition associated to disease states. Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characte…
View article: Construction of circRNA‐based ceRNA network and its prognosis‐associated subnet of clear cell renal cell carcinoma
Construction of circRNA‐based ceRNA network and its prognosis‐associated subnet of clear cell renal cell carcinoma Open
Circular RNAs (circRNAs) are novel biomarkers of various cancers. CircRNAs can sponge miRNAs and regulate target mRNAs, which was called competing endogenous RNAs (ceRNA). This study was designed to identify circRNAs related to patients wi…
View article: Theabrownin inhibits the cytoskeleton‑dependent cell cycle, migration and invasion of human osteosarcoma cells through NF‑κB pathway‑related mechanisms
Theabrownin inhibits the cytoskeleton‑dependent cell cycle, migration and invasion of human osteosarcoma cells through NF‑κB pathway‑related mechanisms Open
Considering the high metastatic potential of osteosarcoma, not only pro‑apoptosis, but also anti‑metastasis is important for anti‑osteosarcoma therapy. Previously, the authors reported the pro‑apoptotic and tumor‑inhibitory effects of thea…