Char L. Panek
YOU?
Author Swipe
View article: Clodronate disodium does not produce measurable effects on bone metabolism in an exercising, juvenile, large animal model
Clodronate disodium does not produce measurable effects on bone metabolism in an exercising, juvenile, large animal model Open
Bisphosphonates are commonly used to treat and prevent bone loss, but their effects in active, juvenile populations are unknown. This study examined the effects of intramuscular clodronate disodium (CLO) on bone turnover, serum bone biomar…
View article: Stem cells and platelet-rich plasma for the treatment of naturally occurring equine tendon and ligament injuries: a systematic review and meta-analysis
Stem cells and platelet-rich plasma for the treatment of naturally occurring equine tendon and ligament injuries: a systematic review and meta-analysis Open
BACKGROUND Platelet-rich plasma (PRP) and mesenchymal stromal or stem cells (MSCs) have been investigated as treatments for equine tendon and ligament injuries, but little consensus exists on the efficacy of these treatments. The study sou…
View article: Lumbar vertebral bone density is decreased in horses with pituitary pars intermedia dysfunction
Lumbar vertebral bone density is decreased in horses with pituitary pars intermedia dysfunction Open
Background Pathological fractures have been reported in equids with pituitary pars intermedia dysfunction (PPID) but their prevalence and pathogenesis is unknown. Objectives To compare: (1) bone mineral density (BMD) in weight bearing and …
View article: Exercising sheep as a preclinical model for musculoskeletal research
Exercising sheep as a preclinical model for musculoskeletal research Open
OBJECTIVE To establish an orthopedic, preclinical, ovine model of controlled exercise using an equine walker. ANIMALS 20 Dorset-Polypay sheep. PROCEDURES Sheep underwent 11 weeks of exercise, 4 days per week. Exercise duration and intensit…
View article: Pharmacokinetics and plasma protein binding of a single dose of clodronate disodium are similar for juvenile sheep and horses
Pharmacokinetics and plasma protein binding of a single dose of clodronate disodium are similar for juvenile sheep and horses Open
OBJECTIVE To determine the single-dose pharmacokinetics of clodronate disodium (CLO) in juvenile sheep and the plasma protein binding (PPB) of CLO in juvenile sheep and horses. ANIMALS 11 juvenile crossbred sheep (252 ± 6 days) for the pha…